growth arrest
Identification of Fitness Determinants during Energy Limited Growth Arrest in Pseudomonas aeruginosa
... Microbial growth arrest can be triggered by diverse factors, one of which is energy limitation due to scarcity of electron donors or ...energy-limited growth arrest and the extent to which ...
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Cell Cycle Exit: Growth Arrest, Apoptosis, and Tumor Suppression Revisited
... group of basic helix-loop-helix (HLH) factors, which induce muscle differentiation and cause growth arrest long before induction of muscle proteins.. Careful analysis of the region invol[r] ...
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Ubiquitin-Dependent Proteolysis of Cyclin D1 Is Associated with Coxsackievirus-Induced Cell Growth Arrest
... Coxsackievirus group B3 (CVB3), an enterovirus of the fam- ily Picornaviridae, is a common human pathogen associated with various diseases, such as myocarditis, meningitis, and pan- creatitis (7, 30, 48). It has been ...
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Analysis of HIV 1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae
... found growth arrest activity ...yeast growth arrest activity. Of note, R77fs showed an impaired growth arrest activity ...yeast growth arrest ...
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Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells
... Treatment of LNCaP-AI cells with ABC294640 or SKi induced a concentration- and time-dependent increase in p53 and p21 expression (Figure 1D, 1E), which are markers of growth arrest and senescence, in ...
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Interaction of influenza virus NS1 protein with growth arrest specific protein 8
... NS1 protein is the only non-structural protein encoded by the influenza A virus, and it contributes significantly to disease pathogenesis by modulating many virus and host cell processes. A two- hybrid screen for ...
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Glycogen synthesis correlates with androgen-dependent growth arrest in prostate cancer
... PC3-AR-V and PC3-AR-E7 cells, which ectopically expresses AR and in case of PC3-AR-E7 the HPV-E7 pro- tein. Additionally, LNCaP, which maintains a functional AR, was tested for glycogen content and its correlation to the ...
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Growth arrest lines and intra epiphyseal silhouettes: a case series
... of growth arrest lines is not fully understood they typically arise during sus- tained periods of disease or biological stress, for ex- ample starvation, septicaemia [7] and chemotherapy ...of arrest ...
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Parasitostatic effect of maslinic acid I Growth arrest of Plasmodium falciparum intraerythrocytic stages
... parasite growth independently of the parasi- tic stage at treatment, indicating that the effect of this compound on the cell cycle is reversible, although cul- tures treated with MA at schizont stage showed the ...
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Growth arrest specific gene 7 is associated with schizophrenia and regulates neuronal migration and morphogenesis
... Our study may suggest that Gas7 regulates neuronal migration as well as neurite initiation and branching, through the ability of its F-BAR domain to deform membranes and form filopodia-l[r] ...
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The role of ceramide in growth arrest and terminal differentiation of human leukaemia cells
... In a recent study we demonstrated that ceramide caused terminal differentiation of the U937 monoblastic leukaemia cells that was characterised by cell cycle arrest and activation of the [r] ...
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Separation of sublethal and lethal effects of the bactericidal/permeability increasing protein on Escherichia coli
... and growth arrest without major impairment of bacterial structure or biosynthetic capabilities, raising the question whether these early effects of BPI are sufficient to cause bacterial ...
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Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling
... Cellular growth properties were investigated in the context of impaired intracellular hypotaurine synthesis (Supplementary Figure ...could arrest the growth of U251 cells ( Figure 2A ), coinciding ...
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Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control
... a growth arrest similar to that caused by rapamycin treatment, suggesting that TOR1 and TOR2 are indeed the targets of FKBP–rapamycin and that the FKBP–rapamycin complex inhibits TOR activity (Kunz et ...
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Suppression of Growth by All-trans Retinoic Acid Requires Prolonged Induction of Interferon Regulatory Factor 1 in Cervical Squamous Carcinoma (SiHa) Cells
... for growth arrest (11, 21, 28). In growth-arrested cells, IRF-1 mRNA expression is markedly elevated, but its expression declines prior to and during DNA synthesis: in this context, IRF-1 is a tumor ...
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Mechanisms and functions of cellular senescence
... senescence growth arrest is often triggered by a persistent DNA damage response (DDR) caused by either intrinsic (oxida- tive damage, telomere attrition, hyperproliferation) or external insults ...
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Activities of stromal and immune cells in HPV-related cancers
... 6: Growth arrest-specific 6; GM-CSF/CSF-2: Granulocyte-macrophage colony- stimulating factor; HGF: Hepatocyte growth factor; HLA: Human leukocyte antigen; HLA-DR: Human leukocyte antigen D related; ...
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Targeting histone methyltransferase and demethylase in acute myeloid leukemia therapy
... The analysis of a large set of different MLL-fusion proteins clearly supported the capacity of a potent menin inhibitor, MI2-2, to induce growth arrest, differentiation, [r] ...
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Original Article Expression of Gax in thoracic aortic aneurysm and its effect on phenotypic transformation of thoracic aortic smooth muscle cells
... of growth arrest-specific homeobox gene (Gax) in thoracic aortic aneurysm (TAA) and its effect on the phenotypic transformation of thoracic aortic smooth muscle cells ...
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Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations
... G1 arrest in three BRAF V600E mutant cell lines, with no effects on the ...the growth arrest effects of each single agent in BRAF V600E mutant cell lines, with an additional inhibitory effect against ...
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