Growth arrest-specific gene
Growth arrest specific gene 7 is associated with schizophrenia and regulates neuronal migration and morphogenesis
... Gas7-deficiency induces schizophrenia-like behavior Schizophrenia is a neurodevelopmental mental disorder characterized by psychotic symptoms and cognitive defi- cits, which include impaired working memory function and ...
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Vitamin K dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity
... Introduction: Growth arrest-specific gene 6 protein (GAS6) and protein S (ProS) are vitamin K-dependent proteins present in plasma with important regulatory functions in systems of response ...
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Role of Tyro3, Axl, and Mer Receptors and Their Ligands (Gas6, and Protein S) in Patients with Hepatocellular Carcinoma
... The Tyro3, Axl and Mer (TAM) receptor tyrosine kinases are activated by endogenous ligands, protein S1 (PROS1) and growth arrest-specific gene 6 (Gas6), and those have important effects on ...
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Methylation associated inactivation of RASSF1A and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma
... suppressor gene RASSF1A was detected in a wide range of human cancers ...cycle arrest, apoptosis, inhibition of cell proliferation in vitro [14-17] as well as repression of tumor formation in nude mice ...
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Modulation of gene expression in endothelial cells by hyperlipaemic postprandial serum from healthy volunteers
... cycle arrest, senescence and apoptosis [44]. The CREB-binding protein gene, crebbp, a transcriptional co-activator that has the capacity to stimulate p53 transcriptional activity, is also overexpressed in ...
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Genetic Dissection of Cell Growth Arrest Functions Mediated by the Epstein-Barr Virus Lytic Gene Product, Zta
... cell growth arrest signaling, and we propose that this occurs through protein-protein interactions with key cell cycle regu- latory ...and growth arrest. Therefore, specific residues ...
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Interaction of influenza virus NS1 protein with growth arrest specific protein 8
... Since the function of Gas8 has not yet been determined, the effect of the association between Gas8 and NS1 on virus infection is unknown. The mammalian Gas8 gene is a possible tumor suppressor that was previously ...
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<p>Novel Tumor Suppressor lncRNA Growth Arrest-Specific 5 (GAS5) In Human Cancer</p>
... insulin-like growth factor 1 receptor (IGF- 1R) proteins and relevant signaling pathways, and reversed the ge fi tinib-resistance lung cancer cells in vitro and in vivo, indicating that GAS5 may overcome the ...
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The multifaceted roles of long noncoding RNAs in pancreatic cancer: an update on what we know
... GAS5: Growth arrest-specific 5; HOTAIR: HOX transcript antisense RNA; HULC: Highly upregulated in liver cancer; HIF-1a: Hypoxia-inducible factor-1α; HMGB1: High mobility group box 1; HPDE: Human ...
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Original Article Expression of Gax in thoracic aortic aneurysm and its effect on phenotypic transformation of thoracic aortic smooth muscle cells
... of growth arrest-specific homeobox gene (Gax) in thoracic aortic aneurysm (TAA) and its effect on the phenotypic transformation of thoracic aortic smooth muscle cells ...
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Cardiac proteomics reveals the potential mechanism of microtubule associated protein 4 phosphorylation-induced mitochondrial dysfunction
... Abcam), growth arrest and DNA-damage-inducible proteins-interacting protein 1 (Gadd45gip1) (16260-1-AP, Proteintech), MAP4 (Cat# A301-489A, Bethyl), and α-tubulin (11224-1-AP, ...
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<p>GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer</p>
... cell growth and proliferation. (A) CCK-8 kit was used to measure the growth ability of BC cells and the results showed that the ability of BC T24 and 5637 cells with GADD45a upregulation was obviously ...
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Herpesvirus Lytic Replication and the Cell Cycle: Arresting New Developments
... cell growth arrest, the tegument protein, UL69 (20, 30) (a homologue of the HSV ICP27 pro- tein which has also been shown to cause growth arrest), and the immediate-early gene product, ...
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The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability
... of gene conversion events by counting the number of GUS-positive cells or ...reporter gene (and most likely also in many other genomic loci), and also that the protein machinery required for homologous ...
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Overexpression of DNA damage-induced 45 α gene contributes to esophageal squamous cell cancer by promoter hypomethylation
... global DNA methylation condition and found global DNA hypomethylation in tumor tissues of ESCC. This finding was consistent with the published studies demonstrating incresed global DNA demethylation through GADD45a ...
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TSF1 to TSF6, required for silencing the Saccharomyces cerevisiae GAL genes, are global regulatory genes.
... pleiotropic growth defects, these results suggest that TSFI to TSF6 are global regulatory genes, and that their respective gene products act independently of specific [r] ...
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The Mold-Specific MS8 Gene Is Required for Normal Hypha Formation in the Dimorphic Pathogenic Fungus Histoplasma capsulatum
... ms8 knockout mutants form aberrant mycelia. ms8 knock- out mutants shifted to 25°C showed no significant phenotypic changes early in the Y-M transformation. Germ tube emer- gence and elongation occurred in both the ...
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Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation
... In the process of vascular assembly, nascent vessels depend on interaction with perivascular cells to establish an endothelial-perivascular complex regulating vessel growth and maturation. Bioengineered tissues ...
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Problems of Arson Investigation Arising Under State Fire Marshal Acts
... In many jurisdictions the fire marshal's power to cause arrest is limited to initiating the complaintA' However, some states have given the fire marshal specific authority to make arrest[r] ...
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Characterization of G1 checkpoint control in the yeast Saccharomyces cerevisiae following exposure to DNA-damaging agents.
... Finally, in an at- tempt to characterize the specific signal(s) that triggers checkpoint arrest we have examined the G, arrest re- sponse to U V or ionizing radiation in mu[r] ...
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