GROWTH-FACTOR-BETA
Parathyroid hormone increases the concentration of insulin like growth factor I and transforming growth factor beta 1 in rat bone
... insulin-like growth factor (IGF)-I, IGF-II, and transforming growth factor beta (TGF-beta) in the proximal tail vertebrae of male ...
9
Hepatic processing of transforming growth factor beta in the rat Uptake, metabolism, and biliary excretion
... Transforming growth factor beta (TGF beta), a recently discovered polypeptide, modulates growth of normal and neoplastic ...TGF beta, we performed studies to examine the hepatic ...
9
Coordinate regulation of transforming growth factor beta gene expression and cell proliferation in hamster lungs undergoing bleomycin induced pulmonary fibrosis
... The number of mesenchymal cells, as well as their ability to synthesize extracellular matrix (ECM) components, greatly increase in the interstitium of fibrotic lungs. We have previously shown that the transcription of ...
8
Transforming growth factor beta regulates thyroid growth Role in the pathogenesis of nontoxic goiter
... and growth regulatory activity of transforming growth factor beta were studied in human thyroid ...transforming growth factor beta was produced in normal and in diseased ...
8
Recombinant latent transforming growth factor beta 1 has a longer plasma half life in rats than active transforming growth factor beta 1, and a different tissue distribution
... Transforming growth factor beta 1 (TGF-beta 1) is a key regulator of cell growth and differentiation. Under normal physiological conditions, it is made as a biologically latent complex ...
10
Original Article Genetic variations of the TNF-α -308 G>A promoter, and TGF-β1 T869C polymorphisms in Egyptian patients with rheumatoid arthritis
... Abstract: Introduction: Rheumatoid arthritis (RA) is a complex autoimmuno disease. Tumor necrosis factor alpha (TNF-α), and transforming growth factor beta 1 (TGF-β1) are responsible for ...
12
Transforming growth factor-beta and endoglin signaling orchestrate wound healing
... transforming growth factor beta (TGF- β ) expression has been demonstrated throughout wound healing and shown to regulate many processes involved in tissue repair, including production of ECM, ...
12
Cellular distribution of transforming growth factor beta 1 and procollagen types I, III, and IV transcripts in carbon tetrachloride induced rat liver fibrosis
... transforming growth factor-beta 1 (TGF-beta 1) and procollagen alpha 1(I), alpha 1(III), and alpha 1(IV) genes were studied in carbon tetrachloride (CCl4)-induced rat liver fibrosis by using ...
12
expression with allergic rhinitis in children with obstructive sleep apnea hypopnea syndrome
... transcription factor T-bet and transforming growth factor beta 1 (TGF-β 1 ) in allergic rhinitis (AR) children with obstructive sleep apnea hypopnea syndrome (OSAHS) as well as their roles in ...
11
Glomerulosclerosis induced by in vivo transfection of transforming growth factor beta or platelet derived growth factor gene into the rat kidney
... single growth factor in the kidney. The introduction of either TGF-beta or PDGF-B gene alone into the kidney induced glomerulosclerosis, although the patterns of action of these growth factors ...
6
Immunohistochemical expression of osteocalcin, transforming growth factor beta 1 and bone morphogenetic protein 7 in fibrous dysplasia and ossifying fibroma of the jaw bones (a comparative study)
... including growth factors, and hormones among others (Sobral et ...cell growth which will either stimulate or inhibit proliferation of mesenchymal cells depending on the presence of other growth ...
5
Regulation of transforming growth factor beta (TGFβ) at the level of nuclear entry
... transcription Factor (RUNX) family members (Hanai 1999, Aliston 2001, Agas 2013), Olf/EBF-associated zink-finger Protein (OAZ) (Hata 2000), Activator Protein 1 (AP1) family (Zhang 1998, Sunqvist 2013), Electron ...
323
Transforming growth factor beta activation in irradiated murine mammary gland
... TGF- beta 1 in tumor xenografts overproducing active TGF-beta 1, without cross-reactivity in tumors expressing similar levels of latent TGF-beta ...TGF- beta 1 increased significantly within 1 ...
9
Transforming growth factor beta and breast cancer: Tumor promoting effects of transforming growth factor β
... TGF-β can stimulate the motility of many cell types in vitro [43–45], therefore suggesting that TGF- β production in vivo may enhance migration of tumor cells and metastatic potential. Indeed, cyclosporine treatment of ...
8
Dog mastocytoma cells produce transforming growth factor beta 1
... Transforming growth factor-beta (TGF beta) promotes deposition of extracellular matrix and is associated with fibrotic conditions both in experimental animals and in ...fibroblast ...
8
Developmental tumours, early differentiation and the transforming growth factor beta superfamily
... Downstream of the receptor complexes are a set of proteins related to the mediator of decapentaplegic (dpp) signalling, called mothers against dpp (MAD) in Drosophila, and to the Sma genes from Caenorhabditis elegans. ...
17
Platelet derived growth factor and transforming growth factor beta synergistically potentiate inflammatory mediator synthesis by fibroblast like synoviocytes
... cytokine-induced growth of FLS is potentiated by PDGF [17] and TGF-β ...of growth fac- tors and cytokines on secretion of inflammatory media- tors by FLS could simply be that a higher number of FLS are ...
11
Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells
... transforming growth factor alpha (TGF alpha), and transforming growth factor beta (TGF beta) was assessed in isolated primary rat intestinal epithelial cells as well as a rat ...
7
Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals
... TGF beta 1 suppressed the evolution of arthritis even when administration was begun after the acute phase of the ...TGF beta 1 treatment greatly reduced inflammatory cell infiltration, pannus formation, and ...
7
Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta
... The present study enlightens a mechanism of feedback loop controlling TGF b responses in human OA chon- drocytes. Contrary to previous studies, which examined one particular gene, we investigated the TGFb-induced ...
13