guanine nucleotide-binding protein
Original Article Guanine nucleotide binding protein-like 3 is a potential prognosis indicator of gastric cancer
... Abstract: Guanine nucleotide binding protein-like 3 (GNL3) is a GIP-binding nuclear protein that has been reported to be involved in various biological processes, including cell ...
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Decreased bioactivity of the guanine nucleotide binding protein that stimulates adenylate cyclase in hearts from cardiomyopathic Syrian hamsters
... coupling of the guanine nucleotide-binding protein that stimulates adenylate cyclase (Gs) to adenylate cyclase. Cyc complementation assays revealed congruent to 50% less Gs activity in cardiac ...
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A potential role for guanine nucleotide binding protein in the regulation of endosomal proton transport
... measuring changes in fluorescence of FITC-dextran. Both GTP and GTP-gamma-S stimulated significantly the initial rate of proton transport. In contrast, GDP-beta-S, which does not activate GTP binding proteins, ...
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Hepatitis B virus X protein interacts with β5 subunit of heterotrimeric guanine nucleotide binding protein
... the binding domain vector, pGBKT7 of ...the binding domain vector in a reaction mixture which included 1 µ l of T4 DNA Ligase and 1 µ l of T4 DNA Ligase Buffer (New England ...
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Guanine nucleotide binding protein, alpha i 3, directly activates a cation channel in rat renal inner medullary collecting duct cells
... GTP binding proteins (G proteins) regulate sodium conducting channels in the apical membrane of renal inner medullary collecting duct (IMCD) cells and thereby modulate sodium ...
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A common variant in the adiponectin gene on weight loss and body composition under sibutramine therapy in obesity
... single nucleotide polymorphism (SNP) in the adrener- gic alpha-2A-receptor (ADRA2A) gene, the C825T (rs5443) SNP in the guanine nucleotide binding protein beta polypeptide 3 (GNB3) ...
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Sirtuins regulate proteomic responses near thermal tolerance limits in the blue mussels Mytilus galloprovincialis and Mytilus trossulus
... increased protein abundance under HS+suramin (Figs 12B and ...vault protein, Rho-GDI and calcyphosin showed an increase in protein abundance under 35°C HS (Figs 12B and ...and guanine ...
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Role of calcium and phosphoinositides in the actions of certain hormones and neurotransmitters
... For example, GTP analogues modify Ca2+-mediated actions in platelets and mast cells 36, 37, and a pertussis toxin that ADP-ribosylates the inhibitory guanine nucleotide binding protein N[r] ...
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SGK and disrupted renal sodium handling in diabetes
... Foetal cal f serum FMRFamide-gated sodium channel Fura-2 acetyoxymethylderivative Gamma Guanine nucleotide-binding protein Glyceraldehyde 3 phosphate dehyrdogenase Glucose transporter Ga[r] ...
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Bradykinin activated membrane associated phospholipase C in Madin Darby canine kidney cells
... a guanine nucleotide-binding protein in receptor-mediated activation of PLC, we evaluated the role of guanine nucleotide proteins in receptor-mediated (bradykinin-stimulated) ...
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The role of the guanine nucleotide binding proteins p21ras in T cell activation and growth
... In addition to looking at the stim ulatory effects of v-H a-ras u pon the IL2 enhancer, w e w ished to discover the relative im portance of ras in the reg u latio n of the IL2 enhancer. Also, w e h o p ed to resolve a ...
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Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells
... dephosphorylation, protein interac- tions and the alteration of protein stability ...a guanine nucleotide exchange factor, as well as the Rac1 effector IQGAP1 has been documented ...several ...
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Vasodilator-Stimulated Phosphoprotein (VASP)-dependent and -independent pathways regulate thrombin-induced activation of Rap1b in platelets
... the guanine nucleotide exchange factors ...the binding of Ca 2+ to its site on CalDAG-GEFI thus confer- ring GEF activity towards Rap1b ...Crk protein is Crk-like ...
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Differential expression of guanine nucleotide binding proteins enhances cAMP synthesis in regenerating rat liver
... Fluctuations in cyclase activity were not explained by variations in glucagon receptor kinetics, but reflected altered G-protein expression. Membrane levels of the stimulatory G- protein, Gs alpha, ...
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Coordinating the activation of RhoA by diverse RhoGEFs : SmgGDS and G-alpha-q-responsive Dbl family guanine nucleotide exchange factors
... Guanine nucleotide binding proteins (G proteins) are a large group of ~100-150 signaling molecules defined by their ability to bind the guanine nucleotides GDP and GTP [1, ...for ...
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Endothelin receptor is coupled to phospholipase C via a pertussis toxin insensitive guanine nucleotide binding regulatory protein in vascular smooth muscle cells
... The mechanisms of endothelin-1 (ET) actions were investigated in cultured rat aortic vascular smooth muscle A-10 cells. The A-10 cells have a single class of high affinity binding sites for ET with an apparent Mr ...
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Molecular Determinants of the Interaction between Coxsackievirus Protein 3A and Guanine Nucleotide Exchange Factor GBF1
... inhibit protein transport were no longer able to inhibit COP-I recruitment because they were unable to bind to GBF1 and trap it on ...of protein transport ...in binding of a cellular ...3A ...
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Targeting phosphoinositide 3-kinase (PI3K) in head and neck squamous cell carcinoma (HNSCC)
... FK506-binding protein; GAP: GTPase activating protein; GEF: Guanine nucleotide exchange factor; GPCR: G protein-coupled receptor; HDAC: Histone deacetylase; HNSCC: Head and neck ...
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9-24-2014 12:00 AM The Role Of The RNA-Binding Protein Rho Guanine Nucleotide Exchange Factor In The Cellular Stress Response
... RNA-binding protein with a role in the stress response, our results show that it does not colocalize with stress granules following either oxidative or osmotic ...the protein dynamics within the ...
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Regulation of RhoA GTPase signaling by guanine nucleotide exchange factors in response to extracellular matrix adhesion and DNA damage
... cell binding domain (CBD) of FN alone, they will form upon addition of an anti-syndecan-4 antibody, which would suggest that syndecan-4 is required for the activation of RhoA ...heparin binding domain (HBD) ...
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