H-K-ATPase (HKA)
Enzymatic Activity of Renal H K ATPase in the Outer Medullary Collecting Duct of Transgenic Mice
... The H-K-ATPase (HKA), a potassium-dependent proton transporter in the outer medullary col- lecting duct (OMCD) plays an important role in acid-base ...two HKA isoforms; gastric (HKAα1), ...
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IN SILICO LIGAND-BASED 2D PHARMACOPHORE GENERATION FOR H+/K+ ATPASE INHIBITORS
... Traditional methods of designing a drug are not appreciated because of time-consuming and costly processes. Nowadays computer aided drug designing is a highly adopted method for drug designing as it replaces the ...
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The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion
... Strial K + flux is NOT carried by basolateral H + ,K + ATPase It was proposed that the basolateral H + ,K + -ATPase contributes to transepithelial K + secretion by ...
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THE H+/K+ ATPase INHIBITORY ACTIVITY OF ETHANOLIC EXTRACT OF DIOSPYROS PANICULATA Dalz BARK
... vitro H + /K + ATPase inhibitory activity of ethanolic extract of Diospyros Paniculata ...(EEDP). H + /K + ATPase inhibition assay was performed by using different concentration ...
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The Antioxidant and H+K+ ATPase Inhibitory Effect of Andrographis Paniculata and Andrographolide In Vitro and In Vivo Studies
... the H + K + ATPase activity of sheep gastric mucosal cells ...mucosal H + K + ATPase activity invitro and the ulcer score ...
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GASTROPROTECTIVE ACTIVITY OF MICHELIA NILAGIRICA IN RATS: POSSIBLE INVOLVEMENT OF H+-K+-ATPASE INHIBITION
... mucosal scrapings of fresh sheep stomach obtained from slaughter house. Immediately after opening the stomach, the mucosa was scrapped to obtain random sample of approximately 100 mg of mucosa. The mucosa was then ...
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Dietary acidification enhances phosphorus digestibility but decreases H+/K+ ATPase expression in rainbow trout
... Most fish species, including rainbow trout, have only a limited ability (~10–80%) to digest P in fish meal (Cho and Bureau, 2001), whereas birds and mammals can digest nearly 100% of P in fish meal (Soares, Jr, 1995). ...
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Increased sensitivity to K+ deprivation in colonic H,K ATPase deficient mice
... two HKA isoforms may be ex- pressed in the colon (29, ...retain K 1 in the co- lon as effectively as cHKA 1/1 mice, clearly demonstrating that cHKA is required for normal K 1 recovery from intestinal ...
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Analysis of the membrane domain of the gastric H(+)/K(+) ATPase
... protein h −1 are routinely ...gastric ATPase, namely around 100 µmol mg −1 h −1 ...of K m for NH 4 + , the cation used to obviate problems of ...
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A Review on Proton Pump Inhibitor for The Treatment of Peptic Ulcer
... (the H + /K + ATPase, or more commonly gastric proton pump) of the gastric parietal ...secreting H + ions into the gastric lumen, making it an ideal target for inhibiting acid ...
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Regulation of collecting tubule adenosine triphosphatases by aldosterone and potassium
... of ATPase activities showed that collecting tubule H/K-ATPase changed inversely with potassium and not with aldosterone whereas H-ATPase changed directly with aldosterone but not ...
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Ouabain insensitive K adenosine triphosphatase in distal nephron segments of the rabbit
... gastric H- K-ATPase). It is concluded that K-ATPase present in the CNT, CCD, and MCD has some properties in common with gastric ...of K- ATPase in the distal nephron ...
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Immunochemical analysis of the vacuolar proton ATPase B subunit in the gills of a euryhaline stingray (Dasyatis sabina): effects of salinity and relation to Na+/K+ ATPase
... The animals used in this study were identical to those used by Piermarini and Evans (Piermarini and Evans, 2000). In brief, ten Atlantic stingrays Dasyatis sabina were captured from the St Johns River, FL, USA (Lake ...
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NaCl uptake by the branchial epithelium in freshwater teleost fish: an immunological approach to ion transport protein localization
... ATPase-immunoreactive cells (MR cells). This observation would contradict the immunogold studies of Sullivan et al. (1995), but in their paper they admit that their observations were not exhaustive and did not ...
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P type Na+/K+ ATPase and V type H+ ATPase expression patterns in the osmoregulatory organs of larval and adult mosquito Aedes aegypti
... colocalizes with P-type Na + /K + -ATPase to the basal membrane of D. melanogaster Malpighian tubules (Sciortino et al., 2001). Evidence for a paracellular Cl – shunt in adult Aedes Malpighian tubules comes ...
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The HKA Test Revisited
... We present a maximum-likelihood-ratio test of the standard neutral model, using multilocus data on polymorphism within species and divergence between species. The model is based on the Hudson-Kreitman- Aguade´ ...
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Regulation of branchial V H+ ATPase, Na+/K+ ATPase and NHE2 in response to acid and base infusions in the Pacific spiny dogfish (Squalus acanthias)
... (for H + -ATPase) of total protein were separated in a ...the H + - ATPase or NHE2 (1:2500 in blocking buffer) with gentle rocking at 4°C ...against H + - ATPase were soaked in ...
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Renal adaptation to potassium in the adrenalectomized rabbit Role of distal tubular sodium potassium adenosine triphosphatase
... their K+ contents, which were 100, 300, 500, and 700 meq/kg in groups 1-4, ...of K+ increased. There was a linear relationship between K+ excretion and the enzyme activity in this ...of K+ ...
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Article #786
... Na, K-ATPase and VASC. Whether Na, K- Comparing the immunohistochemical localization of Na, K-ATPase "α " subunits in normal, BPH and PCa tissues using a pan α monoclonal ...
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Copper induced modulation on the activity of gill ATPases in fingerlings of freshwater fish Oreochromis mossambicus
... bound ATPase is a universal membrane bound enzyme that provides a driving force for any transport ...+ K + ATPase is sensitive to changes either in the lipid or protein component of the ...alters ...
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