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H/sub 4/P/sub 2/O/sub 7/

Epigallocatechin-3-Gallate Protects H2O2-Induced Nucleus Pulposus Cell Apoptosis and Inflammation by Inhibiting cGAS/Sting/NLRP3 Activation

<p>Epigallocatechin-3-Gallate Protects H<sub>2</sub>O<sub>2</sub>-Induced Nucleus Pulposus Cell Apoptosis and Inflammation by Inhibiting cGAS/Sting/NLRP3 Activation</p>

... 1 h, and then incubated with anti-cGAS (1:1000; Cell Signaling Technology), anti-Sting (1:500; Santa Cruz), anti-NLRP3 (1:500; Santa Cruz), caspase-3 (1:500; Cell Signaling Technology), caspase-9 (1:1000; Santa ...

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GPX2 suppression of H2O2 stress regulates cervical cancer metastasis and apoptosis via activation of the &beta;-catenin-WNT pathway

<p>GPX2 suppression of H<sub>2</sub>O<sub>2</sub> stress regulates cervical cancer metastasis and apoptosis via activation of the &beta;-catenin-WNT pathway</p>

... In the process of cervical cancer metastasis, cancer cell migration and invasion are critical initiation steps and can promote a micrometastasis to form a larger secondary tumor. To de fi ne the role of GPX2 in cancer ...

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Protective effects of five compounds from Livistona chinensis R. Brown leaves against hypoxia/reoxygenation, H2O2, or adriamycin-induced injury in H9c2 cells

<p>Protective effects of five compounds from <em>Livistona chinensis</em> R. Brown leaves against hypoxia/reoxygenation, H<sub>2</sub>O<sub>2</sub>, or adriamycin-induced injury in H9c2 cells</p>

... Hence, high-performance liquid chromatography (HPLC) with precolumn 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (HPLC – DPPH) was performed to screen and orient the active ingredients online, followed by using ...

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Prostate Cancer Cellular Uptake of Ternary Titanate Nanotubes/CuFe2O4/Zn-Fe Mixed Metal Oxides Nanocomposite

<p>Prostate Cancer Cellular Uptake of Ternary Titanate Nanotubes/CuFe<sub>2</sub>O<sub>4</sub>/Zn-Fe Mixed Metal Oxides Nanocomposite</p>

... Human prostate cancer PC-3 cell lines were obtained from the American-Type Culture Collection (ATCC, Rockville, MD). Mammalian cell lines: MRC-5 cells (Normal human Lung fi broblast cells) were acquired from VACSERA ...

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Biological responses to core&ndash;shell-structured Fe3O4@SiO2-NH2 nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy

Biological responses to core&ndash;shell-structured Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-NH<sub>2</sub> nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy

... All univariate statistical tests were two-sided, and sig- nificance was set at P,0.05. Multivariate statistical analysis can take internal relationships and mutual influence among variables into account; ...

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Effect of plant extracts on H2O2-induced inflammatory gene expression in macrophages

Effect of plant extracts on H<sub>2</sub>O<sub>2</sub>-induced inflammatory gene expression in macrophages

... (P,0.001) upregulated in a concentration-dependent manner. The mRNA expression of TNF α , NFkB1, NFkB2, and NFE2L2 showed a similar trend, at P,0.01. The interaction between time and dose of incubation was ...

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Effect of Cobalt Precursors on Properties of Co/CoAl2O4 Catalysts Synthesized by Solvothermal Method

Effect of Cobalt Precursors on Properties of Co/CoAl<sub>2</sub>O<sub>4</sub> Catalysts Synthesized by Solvothermal Method

... may not be observed. In fact, the TPR peak locations are affected by reduction kinetics. The kinetics of reduction can be affected by a wide range of variables, including crystallite size, support interaction, and ...

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La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice

<p>La<sub>2</sub>O<sub>3</sub> Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice</p>

... for 2 h at room ...at 4°C, washed 3 times in TBST for 10 min, and incubated with horseradish peroxidase-conjugated goat anti-rabbit IgG or goat anti-mouse IgG antibody (1:1000; Abgent, San Diego, CA, ...

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Biosafety evaluation of Janus Fe3O4-TiO2 nanoparticles in Sprague Dawley rats after intravenous injection

Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection

... molecular weights. Immunoblots for expression of p38, p-p38, JNK, p-JNK, HO-1, ERK, c-Jun, cleaved caspase 3, Bcl2, Bax, P50, p53, Nrf2, Akt, and GAPDH were detected. All antibodies for Western blot in this ...

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Vancomycin-modified Fe3O4@SiO2@Ag microflowers as effective antimicrobial agents

Vancomycin-modified Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@Ag microflowers as effective antimicrobial agents

... 3 O 4 @SiO 2 microsphere-treated solutions did not inhibit the bacterial ...3 O 4 @ SiO 2 –Ag seed showed higher antibacterial efficiency compared with its precursor Fe 3 ...

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In vitro and in vivo targeting imaging of pancreatic cancer using a&nbsp;Fe3O4@SiO2&nbsp;nanoprobe modified with anti-mesothelin antibody

In vitro and in vivo targeting imaging of pancreatic cancer using a&nbsp;Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>&nbsp;nanoprobe modified with anti-mesothelin antibody

... The T2 signal values of experimental group xenograft were decreased by 342.533 ± 42.6 after injection of the target probe, and the control group was decreased by − 61.233 ± 33.9 after injection of saline solution, while ...

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Retrospective analysis of a lactose breath test in a gastrointestinal symptomatic population of Northeast Italy: use of (H2+2CH4) versus H2 threshold

Retrospective analysis of a lactose breath test in a gastrointestinal symptomatic population of Northeast Italy: use of (H<sub>2</sub>+2CH<sub>4</sub>) versus H<sub>2</sub> threshold

... (Table 4), and the same distribution was also seen for symptomatology among methods (Tables 5 and 6), with no subgroup significantly higher than the others within each method (p-value > ...

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Oxygen-Ozone (O2-O3) Therapy in Peripheral Arterial Disease (PAD): A Review Study

<p>Oxygen-Ozone (O<sub>2</sub>-O<sub>3</sub>) Therapy in Peripheral Arterial Disease (PAD): A Review Study</p>

... therapy has been shown to down-regulate oxidative stress and in fl ammatory processes. Markers such as degree of monocyte activation, dityrosine, advanced glycation end products, neopterin, in fl ammatory cytokines were ...

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Nd2O3 Nanoparticles Induce Toxicity and Cardiac/Cerebrovascular Abnormality in Zebrafish Embryos via the Apoptosis Pathway

<p>Nd<sub>2</sub>O<sub>3</sub> Nanoparticles Induce Toxicity and Cardiac/Cerebrovascular Abnormality in Zebrafish Embryos via the Apoptosis Pathway</p>

... pigmentation. 7 Abnormal embryos were also observed in our research, including tail deformity, tail shortening and abnormal oedema (Figure 2C – G), and the embryo mortality and malformation rate increased with the ...

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Polyetherimide-grafted Fe3O4@SiO2 nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging

Polyetherimide-grafted Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging

... 3 O 4 @ SiO 2 nanoparticles, followed by electrostatic adsorption of VEGF ...3 O 4 /SiO 2 /PEI/VEGF shRNA nano- composites exhibited negligible hemolysis against human blood, and ...

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Software Module of Mathematical Chemistry Web Laboratory for Studying the Kinetics of Oxidation of 4 tert Butyl phenol by Aqueous Solution of H2O2 in the Presence of Titanosilicates

Software Module of Mathematical Chemistry Web Laboratory for Studying the Kinetics of Oxidation of 4 tert Butyl phenol by Aqueous Solution of H<sub>2</sub>O<sub>2</sub> in the Presence of Titanosilicates

... of 4-tert-butylphenol by an aqueous solution of hydrogen peroxide in the presence of ...A sub module “The inverse problem” for the solving the inverse kinetic problem with the use of Java-interface for ...

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Local ozone (O2&ndash;O3) versus corticosteroid injection efficacy in plantar fasciitis treatment: a double-blinded RCT

<p>Local ozone (O<sub>2</sub>&ndash;O<sub>3</sub>) versus corticosteroid injection efficacy in plantar fasciitis treatment: a double-blinded RCT</p>

... Patients and methods: This double-blinded randomized trial was performed on 44 adult patients with plantar fasciopathy. One group (23 patients) received local injection of 40 mg methylprednisolone, while a local ...

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Cystone - An ayurvedic polyherbal formulation inhibits adherence of uropathogenic E coli and modulates H2O2 induced toxicity in NRK 52E cells

Cystone - An ayurvedic polyherbal formulation inhibits adherence of uropathogenic E coli and modulates H<sub>2</sub>O<sub>2 </sub>induced toxicity in NRK 52E cells

... No. 2 (20 ml) was poured into petri dishes and allowed to cool in aseptic ...at 4 ° C for 60 minutes for drug diffusion to occur before being incubated at 37 ° C for 24 ...

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Inhibition of ROS-mediated activation Src-MAPK/AKT signaling by orientin alleviates H2O2-induced&nbsp;apoptosis in PC12 cells

Inhibition of ROS-mediated activation Src-MAPK/AKT signaling by orientin alleviates H<sub>2</sub>O<sub>2</sub>-induced&nbsp;apoptosis in PC12 cells

... M H 2 O 2 for 6 hours, and the phosphorylation of Src was evalu- ated using Western ...Following H 2 O 2 stimulation, Src was activated in a time-dependent manner, ...

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Pharmacokinetic parameters and tissue distribution of magnetic Fe3O4 nanoparticles in mice

Pharmacokinetic parameters and tissue distribution of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles in mice

... After intragastric administration, 0.2–0.5 mL of blood from one mouse in each group were collected into an ethylene- diaminetetraacetic acid tube by enucleating eyeballs at the time points of zero minutes, hours 1, 3, 5, ...

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