HA-RAS
Hyperactivation of Ha ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis
... activated Ha-ras could induce urothelial hyperproliferation, leading to simple urothelial ...activated ras in various types of cultured cells often leads to an induction of p16 and/or p19, followed ...
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Anti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in 12 V-Ha-Ras transgenic mouse glioma model
... Since treatment of SF1126 inhibited the migration of glioma cells on vitronectin as well as showed an effect on organization and distribution of the cortical actin- filaments in the glioma cells, we were prompted to ...
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Loss of responsiveness of an AP1-related factor, PEBP1, to 12-O-tetradecanoylphorbol-13-acetate after transformation of NIH 3T3 cells by the Ha-ras oncogene.
... We reported previously that, although the function of the PEBP1-binding site was activated by transiently expressed Ha-ras in untransformed cells, PEBP1 was frequently undetectable by mo[r] ...
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Structure of a Moloney murine leukemia virus-virus-like 30 recombinant: implications for transduction of the c-Ha-ras proto-oncogene.
... Sequence comparison between clones of Mo-VL30, Harvey sarcoma virus Ha-MSV, and genomic c-Ha-ras revealed that all three share a 124-bp region of 87.3% homology.. This region was detecte[r] ...
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Insertion of the v Ha ras oncogene induces differentiation of calcitonin producing human small cell lung cancer
... We have been interested in the genetic and biochemical signals that mediate differentiation of these cell phenotypes in the SCLC lineage and recently have shown that when the viral Harve[r] ...
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Activated Ha-ras can cooperate with defective simian virus 40 in the transformation of nonestablished rat embryo fibroblasts.
... Finally, we demonstrated that in cells producing a nonkaryophilic large T, this protein forms a complex with HSP70, a major heat shock protein.. Although HSP70 is considered a nuclear pr[r] ...
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Different activities of the adenovirus types 5 and 12 E1A regions in transformation with the EJ Ha-ras oncogene.
... * 684 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest We have compared the capacities of the ElA regions of nononcogenic adenovirus type 5 AdS and highly oncogenic Adl2[r] ...
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Initiation of transcription from the minute virus of mice P4 promoter is stimulated in rat cells expressing a c-Ha-ras oncogene.
... This dependence of the outcome of parvovirus infection on the physiological state of host cells can be exemplified by recent studies showing that a number of human and murine cells commi[r] ...
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The role of the guanine nucleotide binding proteins p21ras in T cell activation and growth
... of Ras upon the isolated NFAT binding ...activated ras construct is ...active Ras m utant in transfection had a m arked effect on induction ...
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Dominant inhibitory Ras delays Sindbis virus-induced apoptosis in neuronal cells.
... inhibitory Ras protects naive PC12 cells from apoptotic death induced by serum deprivation by causing a proliferative arrest ...inhibitory Ras protection of PC12 cells against SIN-in- duced apoptosis is ...
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The role of the cytoskeleton in malignant transformation
... Gene Activity Location of gene product Comments Type II: GTP binding proteins Ha-ras GTP-binding autokinase Plasma membrane inner face Normal homologue of Ha-ras and Ki-ras has Ki-ras GT[r] ...
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A REVIEW ON THE ROLE OF ASROCYTE ELEVATED GENE 1 IN CANCER
... of Ha-ras, and this induction was impaired by treatment with PTEN or LY294002 over- expression, specifying that activation of the PI3K signaling pathway modulates Ha-ras-mediated AEG-1 ...for ...
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The neurotensin gene is a downstream target for Ras activation
... of Ha-ras into the human colon cancer line CaCo2 results in the morphologic differentiation to a small bowel ...the Ras regulatory pathway plays a role in the expression of the neurotensin gene ...
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Primary rat cells expressing a hybrid polyomavirus-simian virus 40 large T antigen have altered growth properties.
... Although the ability of SV40 large T antigen to cooperate with activated Ha-ras to form foci is well documented 13, 19, 20, 36, 37, 49, the observation of two types of morphologies for c[r] ...
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Performance of Recycled Asphalt Shingles in Hot Mix Asphalt
... of RAS on the performance of ...of RAS materials and lack of past experiences led to the creation of Transportation Pooled Fund (TPF) Program ...of RAS that include RAS grind size, RAS ...
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Cellular responses to oncogenic Ras signalling
... human Ras proto-oncogenes encode for four highly homologous protein isoforms, H-, K(A)-, K(B)- and N-Ras, that function as molecular switches and timers to transduce signals from activated cell surface ...
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H-Ras and Its Oncogenic Mutants Ras G12V and Ras Q61L
... The side chains of residues Lysine 147, Leucine 120, Aspartic acid 30, and Tyrosine 32 show conformational shifts due to the presence of glycerol molecules (average R.M.S.D. for these four residues 0.22Å versus overall ...
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Syntactic Structures in Research Article Titles from Three Different Disciplines: Applied Linguistics, Civil Engineering, and Dentistry
... regard, RAs are considered as the main vehicle for scholarly communication and circulation of academic knowledge (Peacock, ...2002). RAs are, in fact, gateways for exchanging knowledge in academic ...on ...
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REVIEW OF MAKARDHWAJA RASA IN INFERTILITY .......
... Objective: to review the impor- and methods: literary study is done Sushrut Samhita, Bhaishajya Ratnavali, Ras Ratna Samucchaya, Ras Tarangini, Ras Prakasha Sudhakar, Rasamrita, Rasendra Sar ...
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Analysis of Ras-Induced Overproliferation in Drosophila Hemocytes
... activated Ras in After three washes with PBS, the cells were incubated for Drosophila hemocytes results in sustained cell prolifera- 2 hr at room temperature with a 1:150 dilution of either tion in a manner ...
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