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Haematological Malignancies

Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies

Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies

... Expression of TRPV1 in leukocytes obtained from patients with a range of haematological malignancies, including multiple myeloma (MM) and B-cell non- Hodgkin’s Lymphoma (B-NHL), was then investigated ...

20

EZH2 as a therapeutic target for multiple myeloma and other haematological malignancies

EZH2 as a therapeutic target for multiple myeloma and other haematological malignancies

... EZH2 inhibition has been identified as a promising strat- egy for the treatment of haematological malignancies. Fol- licular lymphoma (FL) and germinal-centre B-cell like (GCB) diffuse large B-cell lymphoma ...

10

Protective Isolation for Patients with Haematological Malignancies: A Pilot Study Investigating Patients’ Distress and Use of Time

Protective Isolation for Patients with Haematological Malignancies: A Pilot Study Investigating Patients’ Distress and Use of Time

... From August 2010 to May 2012, we conducted a descriptive prospective pilot study aimed to evaluate the level of isolation-related distress and the use of free time during the admission into hospital in a cohort of ...

6

Photophatase and tensin homologue deleted on chromosome ten (PTEN) gene mutations in haematological malignancies

Photophatase and tensin homologue deleted on chromosome ten (PTEN) gene mutations in haematological malignancies

... other haematological malignancies are associated with varying degrees to specific genetic lesions, though with the exception of the recently- discovered V617F mutation in the Jak2 Janus kinase gene and ...

264

Hand held dynamometry in patients with haematological malignancies: Measurement error in the clinical assessment of knee extension strength

Hand held dynamometry in patients with haematological malignancies: Measurement error in the clinical assessment of knee extension strength

... Absolute reliability reflects the magnitude of the differ- ences between two measures [32]. Examples of these sta- tistics are the standard error of measurement (SEM), the corresponding 95% confidence interval, the ...

11

Evolving prevalence of haematological malignancies in orphan designation procedures in the European Union

Evolving prevalence of haematological malignancies in orphan designation procedures in the European Union

... of haematological malignancies has been used where possible by the COMP for haematological conditions and was the basis of the conditions selected for this ...

6

Identifying genetic susceptibilities underlying
familial haematological malignancies in a
Tasmanian family resource

Identifying genetic susceptibilities underlying familial haematological malignancies in a Tasmanian family resource

... Researchers involved in the earlier study, particularly the research assistant Jean Panton, observed that a number of the HM patients presenting for treatment were related and accordingly began to informally collect ...

272

Perspectives of bereaved relatives of patients with haematological malignancies concerning preferred place of care and death : a qualitative study

Perspectives of bereaved relatives of patients with haematological malignancies concerning preferred place of care and death : a qualitative study

... Our study provides new insights into end-of-life care for people with haematological malignancies. While almost all relatives said that they had shared patient preferences for home care/death, some ...

14

EHA evaluation of the ESMO—Magnitude of Clinical Benefit Scale version 1.1 (ESMO-MCBS v1.1) for haematological malignancies

EHA evaluation of the ESMO—Magnitude of Clinical Benefit Scale version 1.1 (ESMO-MCBS v1.1) for haematological malignancies

... in haematological malignancies, generating scores that were judged as reasonable by European Hematology Association (EHA) ...between haematological and solid tumour malignancies, are ...

18

Risks of bleeding and thrombosis in intensive care unit patients with haematological malignancies

Risks of bleeding and thrombosis in intensive care unit patients with haematological malignancies

... without haematological malignancies is lower, the exact numbers are not certain, as haematological patients often are included in the general ICU popula- ...bleeding. Haematological patients ...

11

A Study on Infections in Haematological Malignancies and
Disorders Associated with Neutropenia.

A Study on Infections in Haematological Malignancies and Disorders Associated with Neutropenia.

... Certified that the dissertation entitled “A STUDY ON INFECTIONS IN HAEMATOLOGICAL MALIGNANCIES AND DISORDERS ASSOCIATED WITH NEUTROPENIA” is a bonafide work done by Dr. K. USHA KRISHNAN, Postgraduate, ...

117

The frequency of disseminated intravascular coagulopathy in newly diagnosed adult patients with haematological malignancies attending Nanakaly Hospital in Erbil

The frequency of disseminated intravascular coagulopathy in newly diagnosed adult patients with haematological malignancies attending Nanakaly Hospital in Erbil

... with haematological malignancies that were not treated before and they were screened for the presence of DIC on their first ...with haematological malignancies and having received chemo- ...

8

Factors associated with the designation of a health care proxy and writing advance directives for patients suffering from haematological malignancies

Factors associated with the designation of a health care proxy and writing advance directives for patients suffering from haematological malignancies

... Background: During the last few decades, patients ’ rights have been reinforced in many countries by acts of law. Measures now include health care proxies to uphold the doctor-patient relationship and advance directives ...

10

Long-term health-related quality of life of critically ill patients with haematological malignancies: a prospective observational multicenter study

Long-term health-related quality of life of critically ill patients with haematological malignancies: a prospective observational multicenter study

... Over the last few decades, the increased intensity of treatments in patients with haematological malignancies (HMs) has translated into an improved survival rate. As a consequence of more aggressive ...

10

Breast imaging findings in haematological malignancies

Breast imaging findings in haematological malignancies

... of haematological malignancy (via image-guided percutaneous biopsy) negated the need for this form of advanced ...of haematological malignancies in the ...

8

Detection of Legionella Pneumophila in Urine and Serum Specimens of Neutropenic Febrile Patients with Haematological Malignancies

Detection of Legionella Pneumophila in Urine and Serum Specimens of Neutropenic Febrile Patients with Haematological Malignancies

... Infection remains a major problem in cancer patients and neutropenic fever as a common complication of anti neoplastic chemotherapy make these patients more susceptible for infections. 20,21 Among several bacterial ...

5

Ophthalmic manifestations of haematological malignancies

Ophthalmic manifestations of haematological malignancies

... hematological malignancies has considerably ...hematological malignancies may involve many ocular tissues either by direct infiltration, hemorrhage, ischemia, or toxicity due to various chemotherapeutic ...

79

Perceived social support and associations with health-related quality of life in young versus older adult patients with haematological malignancies

Perceived social support and associations with health-related quality of life in young versus older adult patients with haematological malignancies

... Data were collected as part of a prospective, longitudinal study. In this study, young adult cancer patients were surveyed at two measuring time points using the base- line survey (t1). Participants had to meet the ...

10

Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies

Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies

... malignant haematological cell lines, and 2) to determine if any effect was mediated through its cellular receptor, transient receptor potential vanilloid-1 ...

225

Investigating the genetic predisposition for familial haematological malignancies

Investigating the genetic predisposition for familial haematological malignancies

... From these studies three classes of predisposition risk for breast cancer have emerged: firstly people with BRCA1 and BRCA2 mutations have high-penetrance predisposition alleles; secondl[r] ...

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