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hair bundle

Development of the hair bundle and mechanotransduction

Development of the hair bundle and mechanotransduction

... the hair bundle one can find tip links, horizontal top connectors, shaft connectors and ankle ...mature hair cells and from all stereocilia except those in the tallest row, a single, ...

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Periodic, moderate water flow reversibly increases hair bundle density and size in Nematostella vectensis

Periodic, moderate water flow reversibly increases hair bundle density and size in Nematostella vectensis

... employ hair bundles on hair cells to detect flow, vibrations and ...gravity. Hair bundles on sea anemone tentacles detect nearby vibrations in the water column produced by prey movements and then ...

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Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape

Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape

... The surface of the organ of Corti acquires its organization in rows of sensory cells and supporting cells between embryonic day E14.5 and birth in the mouse by a convergent extension process that is thought to involve ...

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Aberrant cochlear hair cell attachments caused by Nectin 3 deficiency result in hair bundle abnormalities

Aberrant cochlear hair cell attachments caused by Nectin 3 deficiency result in hair bundle abnormalities

... sensory hair cells (HCs) interdigitated with nonsensory supporting cells (SCs) to form a checkerboard-like cellular ...with hair bundles on their apical ...the hair bundles and the positioning of the ...

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Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear

Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear

... Gipc1 is a PDZ-domain-containing protein that can bind to proteins that have a conserved type I PDZ-BM at their carboxy termini. Gipc1 can then bind to MyoVI through its C-ter domain (Bunn et al., 1999), and MyoVI can ...

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A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth

... wild-type hair bundles during development. Hair bundles from ...differentiated hair cells, with a particular concentration at their actin-free distal end ...surrounding hair cell microvilli, ...

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A link between planar polarity and staircase like bundle architecture in hair cells

A link between planar polarity and staircase like bundle architecture in hair cells

... uniform bundle orientation across HCs (May-Simera and Kelley, ...the bundle and the off-center position of the kinocilium) depends on ciliary proteins, small GTPases and the Insc-LGN-G α i complex (Bhonker ...

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Kif3a regulates planar polarization of auditory hair cells through both ciliary and non ciliary mechanisms

Kif3a regulates planar polarization of auditory hair cells through both ciliary and non ciliary mechanisms

... sensitivity, hair bundles in the cochlea must be uniformly oriented for correct perception of ...V-shaped hair bundle on every hair cell points toward the lateral edge of the cochlear ...

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Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization

Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization

... V-shaped hair bundles atop auditory hair cells and their uniform orientation are manifestations of epithelial planar cell polarity (PCP) required for proper perception of ...the hair cell-intrinsic ...

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The Actin-Binding Proteins Eps8 and Gelsolin Have Complementary Roles in Regulating the Growth and Stability of Mechanosensory Hair Bundles of Mammalian Cochlear Outer Hair Cells

The Actin-Binding Proteins Eps8 and Gelsolin Have Complementary Roles in Regulating the Growth and Stability of Mechanosensory Hair Bundles of Mammalian Cochlear Outer Hair Cells

... development and/or maintenance of hair bundle structure and function [6,31]. Among these proteins, Eps8 and twinfilin 2 are directly involved in stereocilia growth since when absent (Eps8 [12]) or ...

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Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function

Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function

... mature hair bundle (Kaltenbach et al, ...OHC hair bundles (Geller et al, 2009; Geng et al, 2009, 2012; Dulon et al, ...IHC hair cell bundles in clarin-2-defi- cient mice appear to grow ...

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Piezo1 haploinsufficiency does not alter mechanotransduction in mouse cochlear outer hair cells

Piezo1 haploinsufficiency does not alter mechanotransduction in mouse cochlear outer hair cells

... The hair cells of the organ of Corti within the mammalian cochlea convert mechanical stimuli into receptor ...The hair bundle atop each cell contains multiple rows of stereocilia of increasing ...

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Anatomical and functional recovery of the goldfish (Carassius
auratus) ear following noise exposure

Anatomical and functional recovery of the goldfish (Carassius auratus) ear following noise exposure

... of hair bundle loss, four regions of each saccule were chosen for study based on preliminary results that indicated differences in the degree of bundle loss across the rostral–caudal axis of the ...

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Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

... the hair bundle defect in PCDH15-DCD2 mice, we raised antibodies against PCDH15-CD2 and analyzed its expression in hair cells at ...throughout hair bundles of OHCs; we also observed expression ...

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Mutations in Protocadherin 15 and Cadherin 23 Affect Tip Links and Mechanotransduction in Mammalian Sensory Hair Cells

Mutations in Protocadherin 15 and Cadherin 23 Affect Tip Links and Mechanotransduction in Mammalian Sensory Hair Cells

... to bundle displacements, together with our Figure ...a bundle from the heterozygote showing links emanating from the tips of the shorter stereocilia and connecting to the sides of the taller stereocilia ...

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Hair simulation and rendering

Hair simulation and rendering

... Human hair is composed on average of 100 000 to 150 000 hairs implanted alone or in groups of two or three in the ...of hair on the head depends on several factors: the diameter and colour of hair, ...

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STANDARDIZATION PARAMETER OF DIFFERENT MARKETED HERBAL HAIR OIL

STANDARDIZATION PARAMETER OF DIFFERENT MARKETED HERBAL HAIR OIL

... Viscosity is a measure of the resistance of a fluid which is being deformed by either stress or tensional stress. Thoroughly clean the viscometer. Mount the viscometer in vertical position on a suitable stand. Fill dry ...

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Alopecia: introduction and overview of herbal treatment

Alopecia: introduction and overview of herbal treatment

... Telogen effluvium (TE) is an increased loss of normal club hairs that occurs by a perturbation of the hair cycle [16]. It was first described by Kligman in 1961 and his hypothesis was that whatever the cause of ...

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A new look at the ventral nerve centre of Sagitta: implications for the phylogenetic position of Chaetognatha (arrow worms) and the evolution of the bilaterian nervous system

A new look at the ventral nerve centre of Sagitta: implications for the phylogenetic position of Chaetognatha (arrow worms) and the evolution of the bilaterian nervous system

... medial bundle (MB), the bilaterally paired intermediate bundles (IB), and the paired lateral bundles (LB; ...medial bundle (solid arrow in ...medial bundle whereas the third one joins the ...

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Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium

Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium

... 8. Petri H, Pierchalla P, Tronnier H. Die Wirksamkeit der medikamentösen Therapie bei strukturellen Läsionen der Haare und bei diffuser Effluvium - vergleichende Doppelblindstudie. [The efficacy of drug therapy in ...

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