hBD-1
Tissue-specific human beta-defensins (HBD)-1, HBD-2 and HBD-3 secretion profile from human amniochorionic membranes stimulated with Candida albicans in a two-compartment tissue culture system
... that: 1) primary amnion epithelial cells express messenger RNA for HBD-1 to 3, as well as secretory leukocyte protease in- hibitor (SLPI) and ...significantly HBD-2 [16]; ...of HBD-3 ...
11
High level expression of human epithelial β defensins (hBD 1, 2 and 3) in papillomavirus induced lesions
... including hBD-1, hBD-2, and hBD-3 are widely expressed in epithelial cells ...expressed hBD-1 and induced hBD-2 and hBD-3 have been shown to be microbicidal to a ...
8
Tissue-specific human beta-defensins (HBD)1, HBD2, and HBD3 secretion from human extra-placental membranes stimulated with Escherichia coli
... During normal pregnancy, the fetus grows and develops in an immunologically privileged environment, part of this privilege is associated with the intrinsic capacity of the maternal-fetal interface to respond promptly and ...
8
Increased human defensine levels hint at an inflammatory etiology of bisphosphonate associated osteonecrosis of the jaw: An immunohistological study
... that hBD-1 may be modulated by inflammation, while hBD-2 and hBD-3 are expressed by cells upon stimulation with proinflammatory cytokines and by microorganisms ...[24]. hBD-1 can ...
8
The Porcine Humoral Immune Response against Pseudorabies Virus Specifically Targets Attachment Sites on Glycoprotein gC
... (8). HBD 2 and HBD 3 of gC are separated by more than 30 amino acids, and therefore, it is likely that antibodies directed against only one HBD are not sufficient to block attachment of the ...
9
Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer’s brain
... Mammalian β-defensins are an evolutionarily conserved group of cationic, non-glycosylated antimicrobial and immunomodulatory peptides that are expressed in all mammals, including humans [1,2]. Constitutively ex- pressed ...
11
Development of TAP, a non-invasive test for qualitative and quantitative measurements of biomarkers from the skin surface
... between the micro-array and skin, makes TAP insensitive to gravity issues e.g. such as observed using skin-lavage techniques. In addition, the relatively small size of the TAP micro-array allows measurements of small ...
12
Human beta defensin 1: an antimicrobial peptide of urogenital tissues
... mature HBD-1 peptide was originally isolated from human blood filtrate, and the corresponding cDNA fragment was cloned from kidney and vaginal cDNA libraries ...of HBD-1 expression, we ...
11
Isolation of human β-defensin-4 in lung tissue and its increase in lower respiratory tract infection
... cells. hBD-1 is expressed constitutively in the epithelia of the urogenital tract, trachea, and respiratory tract ...[2-4]. hBD-2 and hBD- 3, isolated from psoriatic scale extracts [5,6], are ...
9
Original Article Effect of Yiqi Wenyang Huwei decoction on ovalbumin-induced bronchial asthma in rats
... [39]. HBD-1 and HBD-2 can destroy Escherichia coli and other Gram-negative bacteria at a cer- tain concentration, but the bactericidal effect on Gram-positive bacteria is relatively ...weak. ...
11
Human β Defensins 2 and 3 Demonstrate Strain Selective Activity against Oral Microorganisms
... tissue, HBD-1 and HBD-2 mRNAs are localized predominately in the suprabasal stratified epithelium and the peptides detected in upper epi- thelial layers, consistent with the formation of the ...
6
Expression of human beta defensins 1 and 2 in kidneys with chronic bacterial infection
... (HBD-1, HBD-2, HBD-3, HBD-4) have been characterized in humans. HBD-1 was first iso- lated from the hemofiltrate of patients with end stage kid- ney disease undergoing ...
10
Impact of the Hoa Binh dam (Vietnam) on water and sediment budgets in the Red River basin and delta
... In order to estimate water and sediment discharge from es- tuaries into the coastal zone before and after HBD impound- ment, a data-driven modelling approach was set up using the MIKE11 model (Vu et al., 2011). ...
19
Ligand based Pharmacophore Modeling of some Angiotensin II Receptor Antagonist
... The present study done on Angiotensin II receptor antagonist for identifying common chemical features to generate a pharmacophore has broadened our vision for discovery of more specific drugs to be used as ...
6
Hepatocytes express the antimicrobial peptide HBD 2 after multiple trauma: an experimental study in human and mice
... The aim of this study was to detect possible sources for HDP in plasma of multiple injured patients and to find inducers and mechanisms of induction. As liver constitutes an organ, which is vulnerable to trauma damage ...
9
Dissecting The Molecular Basis Of The Scaffold Protein Jade In Hbo1 Histone Acetyltransferase (hat) Activity
... It was previously demonstrated that an N-terminal region of JADE1 between residues 90- 199 participated in HBO1 catalytic activity(Avvakumov et al., 2012). This region of JADE1 contains sequence conservation within ...
114
An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community
... degraded these downstream intermediates of 4-DM less efficiently than the other community members. On the other hand, non-degraders, e.g., the Pseudomonas sp., could utilize the intermediates more quickly, therefore ...
13
Solvent effect on the spectral properties of Neutral Red
... The present study deals with the solvent effect on the absorption spectra of Neutral Red (NR), which belongs to Quinone-Imine class of dyes. The molecular structure of this dye is shown in figure 1. Absorption ...
8
Serum inflammatory biomarkers fail to identify early axial spondyloarthritis: results from the SpondyloArthritis Caught Early (SPACE) cohort
... First, we compared CRP, ESR and calprotectin levels in patients of the SPACE cohort ful fi lling the ASAS criteria versus those who did not ful fi l the criteria. Second, we per- formed a subanalysis between patients ful fi ...
6
Rapid regulation of protein activity in fission yeast
... that HBD-tagged heterologous proteins are subject to hormonal regulation [13] a large number of proteins from various organisms has been tagged ...the HBD close to the kinase domain of Wee1, expecting it to ...
11