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HBV replication

Enchanced levels of apolipoprotein M during HBV infection feedback suppresses HBV replication

Enchanced levels of apolipoprotein M during HBV infection feedback suppresses HBV replication

... on HBV gene expression and viral replication in cell culture models by using ...the HBV genome on its chromosome. The effects of ApoM on HBV gene expression and viral replication were ...

6

Review Article Regulatory mechanisms for HBV replication

Review Article Regulatory mechanisms for HBV replication

... regulate HBV replication via differ- ent ...suppresses HBV DNA rep- lication without inducing cell lysis by disrupting the formation or stability of cytoplasmic viral capsids through activation of ...

9

The hepatitis B virus (HBV) precore protein inhibits HBV replication in transgenic mice.

The hepatitis B virus (HBV) precore protein inhibits HBV replication in transgenic mice.

... that replication efficiency may also be af- fected by the relative abundance of the various individual spe- cies of ...during HBV infection. Inhibition of HBV replication is independent of ...

6

Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1 -dependent pathway

Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1 -dependent pathway

... inhibit HBV RNA transcription and DNA replication [49, ...enhance HBV production, but higher concentration (more than 200 nM) resulted in decrease HBsAg level ...affect HBV gene expression ...

16

The Hepatitis B Virus (HBV) HBx Protein Activates AKT To Simultaneously Regulate HBV Replication and Hepatocyte Survival

The Hepatitis B Virus (HBV) HBx Protein Activates AKT To Simultaneously Regulate HBV Replication and Hepatocyte Survival

... on HBV replication ...influence HBV replication did not, in turn, determine whether HBV replication or expression of HBV proteins affected the PI3K/AKT pathway (43, ...the ...

14

HBV replication is significantly reduced by IL-6

HBV replication is significantly reduced by IL-6

... of HBV-related clinical progression as compared with several other ...(HBV) replication and prevent the accumulation of HBV covalently closed circular DNA (cccDNA) in a human hepatoma cell ...

9

Identification of acetyltransferase genes (HAT1 and KAT8) regulating HBV replication by RNAi screening

Identification of acetyltransferase genes (HAT1 and KAT8) regulating HBV replication by RNAi screening

... of HBV-DNA between 72 and 96 h when HAT1 or KAT8 was knocked ...between HBV-DNA and liver histology in the different statuses of HBeAg patients ...without HBV-DNA was existed [22], suggesting that ...

9

Differential Impact of Immune Escape Mutations G145R and P120T on the Replication of Lamivudine-Resistant Hepatitis B Virus e Antigen-Positive and -Negative Strains

Differential Impact of Immune Escape Mutations G145R and P120T on the Replication of Lamivudine-Resistant Hepatitis B Virus e Antigen-Positive and -Negative Strains

... of HBV vectors. The 1.28-fold replication-competent HBV plas- mid (genotype A, subtype adw2) served as a wild-type (WT) vector (25), and the rtM204I and rtL180M/rtM204V LAM-resistant vectors had been ...

8

Dynamics of HBV cccDNA expression and transcription in different cell growth phase

Dynamics of HBV cccDNA expression and transcription in different cell growth phase

... of HBV replication at different cell growth stages, the confluent ...the HBV replication profiles were determined by ...between HBV replication and cell growth stages more ...

16

Cloning and Characterization of a Novel Hepatitis B Virus x Binding Protein That Inhibits Viral Replication

Cloning and Characterization of a Novel Hepatitis B Virus x Binding Protein That Inhibits Viral Replication

... the HBV enhancers/core promoter compared to activation of the luciferase gene by the AP-1-responsive ele- ...this HBV-host protein interaction and its regulatory role of HBV ...

7

Association of HBV DNA replication with antiviral treatment outcomes in the patients with early-stage HBV-related hepatocellular carcinoma undergoing curative resection

Association of HBV DNA replication with antiviral treatment outcomes in the patients with early-stage HBV-related hepatocellular carcinoma undergoing curative resection

... low HBV DNA ...chronic HBV infection, evidence of active viral rep- lication (≥2000 IU/mL), and elevated levels of ALT ...low HBV replication should be given antiviral ...of HBV-related ...

14

Relative Abundance of Integrant-Derived Viral RNAs in Infected Tissues Harvested from Chronic Hepatitis B Virus Carriers

Relative Abundance of Integrant-Derived Viral RNAs in Infected Tissues Harvested from Chronic Hepatitis B Virus Carriers

... of HBV are FIG 13 Potential contribution of id-RNAs to the life cycle of ...the HBV life cycle is based on the one that was reported previously by Mason et ...of HBV virions contain rcDNA inside the ...

39

ZEB2 inhibits HBV transcription and replication by targeting its core promoter

ZEB2 inhibits HBV transcription and replication by targeting its core promoter

... and HBV has not been fully ...in HBV-expressing cells. Overexpression of ZEB2 inhibited HBV DNA replicative intermediates, ...promoted HBV replication. Furthermore, ZEB2 could bind to ...

9

DDX3 DEAD-Box RNA Helicase Inhibits Hepatitis B Virus Reverse Transcription by Incorporation into Nucleocapsids

DDX3 DEAD-Box RNA Helicase Inhibits Hepatitis B Virus Reverse Transcription by Incorporation into Nucleocapsids

... to HBV Pol, we utilized affinity purification of HBV Pol fol- lowed by mass spectrometry to identify copurified host ...expresses HBV Pol was generated, as detailed in Materials and Methods, using an ...

10

Inhibition of Hepatitis B Virus Gene Expression and Replication by Hepatocyte Nuclear Factor 6

Inhibition of Hepatitis B Virus Gene Expression and Replication by Hepatocyte Nuclear Factor 6

... inhibit HBV gene expression and DNA ...enhanced, HBV gene expression and replication in hepatoma ...the HBV genome (nucleotides [nt] 3009 to 3019) was responsible for the inhibition of the SP2 ...

11

In Vitro Studies Show that Sequence Variability Contributes to Marked Variation in Hepatitis B Virus Replication, Protein Expression, and Function Observed across Genotypes

In Vitro Studies Show that Sequence Variability Contributes to Marked Variation in Hepatitis B Virus Replication, Protein Expression, and Function Observed across Genotypes

... The replication phenotype of this novel variant had not been previously ...Our replication-competent clones have enabled the first meaningful comparison of replica- tion phenotype between European and Asian ...

11

CRTC2 enhances HBV transcription and replication by inducing PGC1α expression

CRTC2 enhances HBV transcription and replication by inducing PGC1α expression

... composition, HBV transcription and replication can be regulated by nutri- tional signals that control hepatic glucose metabolism ...in HBV transcription and ...for HBV replication ...

8

Posttranscriptional regulation of hepatitis B virus replication by the precore protein.

Posttranscriptional regulation of hepatitis B virus replication by the precore protein.

... inhibits HBV DNA ...of HBV replication was ...of HBV DNA than transfection in HuH-7 cells; the patterns of replicative forms in the two cell lines were ...conditions, HBV ...

9

DDX3 DEAD-Box RNA Helicase Is a Host Factor That Restricts Hepatitis B Virus Replication at the Transcriptional Level

DDX3 DEAD-Box RNA Helicase Is a Host Factor That Restricts Hepatitis B Virus Replication at the Transcriptional Level

... both HBV replication and core protein expres- ...suppresses HBV replication in HepG2 cells ...nated HBV-Tof, in which HBV pgRNA is expressed under the control of a ...

10

Robust Human and Murine Hepatocyte Culture Models of Hepatitis B Virus Infection and Replication

Robust Human and Murine Hepatocyte Culture Models of Hepatitis B Virus Infection and Replication

... the HBV receptor (also the hepatitis delta virus [HDV] receptor) has been a landmark advance in HBV research in recent years ...to HBV infection and replication, albeit inefficiently ...support ...

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