HCO3− secretion
Secretagogues stimulate electrogenic HCO3– secretion in the ileum of the brushtail possum, Trichosurus vulpecula: evidence for the role of a Na+/HCO3– cotransporter
... In the intestine of eutherian mammals the transport proteins associated with absorption and secretion are predominately expressed in the villous and crypt cells, respectively (Field, 2003). To determine whether ...
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Molecular mechanisms for intestinal HCO3− secretion and its regulation by guanylin in seawater acclimated eels
... fluid osmolality (Grosell et al., 2005; Wilson et al., 2002, 2009). Hormones such as growth hormone/IGF-I and cortisol, which re-organize osmoregulatory organs to a SW-type, have long been implicated in SW adaptation ...
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IRBIT coordinates epithelial fluid and HCO3– secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct
... Knockdown of IRBIT inhibits pancreatic duct fluid secretion. (A) RT-PCR of IRBIT mRNA in sealed ducts treated with scrambled (Scr) or 3 IRBIT dicer siRNA is shown. (B) Fluid secretion in ducts perfused in ...
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Renoguanylin stimulates apical CFTR translocation and decreases HCO3− secretion through PKA activity in the Gulf toadfish (Opsanus beta)
... The guanylin peptides – guanylin, uroguanylin and renoguanylin (RGN) – are endogenously produced hormones in teleost fish enterocytes that are activators of guanylyl cyclase-C (GC-C) and are potent modulators of ...
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The involvement of H+ ATPase and carbonic anhydrase in intestinal HCO3– secretion in seawater acclimated rainbow trout
... base secretion in the presence of amiloride does not exclude the possibility that an apical NHE3 isoform is active in the pyloric caeca and anterior intestine, as certain NHE isoforms and splice variants appear to ...
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Active HCO3 Secretion in the Rectal Salt Gland of a Mosquito Larva Inhabiting NaHCO3 CO3 Lakes
... To determine actual HCO3~ and COSS~ concentrations in rectal secretion and to calculate transepithelial HCOS~ and CO3*~ gradients across the rectal wall, we subsequently measured total C[r] ...
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High rates of HCO3– secretion and Cl– absorption against adverse gradients in the marine teleost intestine: the involvement of an electrogenic anion exchanger and H+ pump metabolon?
... Considering the clear elevation of rectal base excretion by toadfish exposed to 50 p.p.t. compared with seawater (Genz et al., 2008), it is perhaps surprising that no significant elevation in the expression of tfSLC26a6 ...
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Cyclic adenosine monophosphate stimulated anion transport in rabbit cortical collecting duct Kinetics, stoichiometry, and conductive pathways
... stimulates HCO3 secretion and Cl self-exchange in rabbit cortical collecting ...mM). HCO3 secretion also showed saturation kinetics as a function of mean luminal [Cl] (Km, 4-11 ...basolateral ...
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Adaptation of rabbit cortical collecting duct HCO3 transport to metabolic acidosis in vitro
... net HCO3- flux before and after incubating CCDs 1 h at pH ...reversed HCO3- flux from net secretion to absorption, whereas incubation for 3 h at pH ...net HCO3- secretion by ...
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Effect of proximal gastric vagotomy on calculated gastric HCO3 and nonparietal volume secretion in man Studies during basal conditions and gastrin 17 infusion
... gastric HCO3- and H+ secretion, as well as nonparietal and parietal volume secretion, in 15 duodenal ulcer patients who had previously undergone successful proximal gastric vagotomy, 15 unoperated ...
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Tracing Putative Trafficking of the Glycolytic Enzyme Enolase via SNARE-Driven Unconventional Secretion
... the secretion of these glycolytic enzymes differs from that of the Acb1 ...the secretion of glycolytic enzymes in ...the secretion of ...protein secretion in combination with Sec14p (35), and ...
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Basolateral membrane sodium independent Cl /HCO3 exchanger in rat inner medullary collecting duct cell
... luminal HCO3- had a significantly smaller effect, indicating that the HCO3-/H+ permeability of the basolateral membrane is much larger than the apical ...bath HCO3-, a measure of basolateral ...
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The renal electrogenic Na+:HCO 3 cotransporter
... The renal electrogenic Na+:HCO3− cotransporter, which has a Na+:HCO3− stoichiometry of 1:3, is the major route for transferring HCO3− from the proximal-tubule cell to the blood and is re[r] ...
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GABAA Coupled Cl / HCO3 ATPase from Plasma Membrane of the Rat Brain: Role of HCO3 in the Enzyme Activation
... A Effect of Cl− concentration on the the “basal” Mg2+-ATPase activity of rat brain plasma membranes in the absence or in the presence of 20 mM HCO3− and B The Cl−-, Cl− + HCO3− - and HCO[r] ...
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The Critical Importance of Urinary Concentrating Ability in the Generation of Urinary Carbon Dioxide Tension
... + secretion and decreased concentrating ability ...+ secretion and decreased concentrating ability, Brattleboro (BB) rats, and (c) the presence of both impaired H + secretion and concentrating ...
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Ammonia excretion in mytilid mussels is facilitated by ciliary beating
... The present study investigated the organs and principles of TAM excretion in mytilid bivalves. Immunolocalization revealed that an Rh protein is expressed in apical membranes of cells in both the plicate organ and the ...
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AN ANALYSIS OF THE MECHANISM OF THE INHIBITORY INFLUENCE OF K+ ON RENAL H+ SECRETION
... One system, termed the pCO2-dependent H+ secretory system, has a maximal HCO3- reabsorptive capacity HCO3- Tm which is dependent upon plasma CO2 tension and independent of carbonic anhyd[r] ...
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Intracellular pH regulation in rabbit renal medullary collecting duct cells Role of chloride bicarbonate exchange
... preincubated in bicarbonate-containing solutions and then abruptly diluted into bicarbonate- free media. The MCD cell pHi response to abrupt removal of CO2/HCO3 included an initial alkalinization due to rapid CO2 ...
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Computational modelling predicts substantial carbon assimilation gains for C 3 plants with a single celled C 4 biochemical pump
... pH in chloroplast stroma pH in the cytoplasm pH within the vacuole CO2 ↔HCO3 - conversion rate boost due to CA Base rate for CO2 +H2 O→HCO3 - +H+ reaction Base rate for CO2 +OH- →HCO3 - [r] ...
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Corrosion Behaviour of Tinplate in Synthetic Industrial Water
... Effect of HCO3- concentration The effect of adding increasing amounts of HCO3- anions to synthetic medium on the anodic and cathodic polarization curves of tinplate was investigated figu[r] ...
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