Healthy Human Volunteers
PHARMACOKINETIC EVALUATION OF ONCE DAILY SUSTAINED RELEASE DEXTROMETHORPHAN HYDROBROMIDE (DM) AND IMMEDIATE RELEASE DM IN HEALTHY HUMAN VOLUNTEERS
... six healthy human volunteers after single oral administration and compared with an immediate release tablets (IR) in randomized three-period crossover ...
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Comparison of the effects of cimetidine and hyoscine-n-butyl bromide on paracetamol pharmacokinetics in healthy human volunteers
... in healthy human volunteers is about 2 hours and the minimum sampling duration acceptable for pharmacokinetic studies is three (3) times the half life of the drug and this was adapted in the ...
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Evaluation of Antioxidant, Lipid Peroxidation and Toxic Effects after Pomegranate Intake in Healthy Human Volunteers
... many human diseases [2] ...promising human data, the present study aimed to further strengthen support for the unique anti- oxidant and antiperoxidative properties of this healthy ...in ...
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BIOEQUIVALENCE STUDY OF DOFETILIDE IN HEALTHY HUMAN VOLUNTEERS UNDER FASTING AND FED CONDITIONS
... Dofetilide is an antiarrhythmic agent belonging to class III. It is indicated for the conversion and maintenance of sinus rhythm in atrial fibrillation and atrial flutter. The objective of this study is to investigate ...
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EVALUATION OF EFFECT OF GREEN TEA AND SAFFRON ON LEARNING PROCESS AND MEMORY IN HEALTHY HUMAN VOLUNTEERS
... Learning process and memory are important physiological parameters during our growth and play important role at various circumstances. These could be in situations like increased demand and needs as occurs during ...
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Diesel exhaust modulates ozone-induced lung function decrements in healthy human volunteers
... instance, healthy human volunteers exposed to 300 μg/m 3 DE for one hour with intermittent exercise resulted in marked systemic and pulmonary inflamma- tory responses ...
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Brain Targeted Transcranial Administration of Diazepam and Shortening of Sleep Latency in Healthy Human Volunteers
... in healthy human volunteers using electroencephalography techniques by assessing the ability of transcranially administered diazepam in bringing about b activity in the electroencephalographic wave ...
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Bioavailability and Bioequivalence Study of Antiepileptic Drug in Healthy Human Volunteers
... normal, healthy subjects (18-55 yr), each of whom receive both the treatments alternately, in a crossover fashion (two-period, two-treatment crossover design), with the two phases of treatment separated by a ...
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Topical application of RTA 408 lotion activates Nrf2 in human skin and is well-tolerated by healthy human volunteers
... Thus, human kerati- nocytes are an important cell type to investigate toler- ability of RTA 408 and whether RTA 408 can elicit suitable pharmacologic activation of the Nrf2-mediated antioxidant ...primary ...
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BIOEQUIVALENCE STUDY OF TRAMADOL + PARACETAMOL (37.5 + 325 MG) IN HEALTHY HUMAN VOLUNTEERS IN FASTING CONDITION
... All subjects were examined for inclusion and exclusion criteria based on clinical examinations, recording of 12-lead electrocardiogram and laboratory investigations of blood and urine within the 21 days prior to first ...
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Pharmacokinetic Evaluation of a Gastrointestinal Motility Tretment of Drug in Healthy Human Volunteers (Cinitapride)
... evaluated under "stressed conditions". If it is shown that competitive products are bioequivalent under both fasting and fed conditions, there is greater confidence that they are therapeutically equivalent when ...
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Effect of Honey on CYP3A4 Enzyme and P-Glycoprotein Activity in Healthy Human Volunteers
... ministration on CYP3A4 and P-gp activity in healthy volunteers using carbamazepine and digoxin as their.. 15.[r] ...
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Journal of Applied Pharmaceutical Science
... 30 healthy human volunteers following oral administration of 3 x 100mg of Pregabalin marketed formulation as a part of pharmacokinetic ...these volunteers under fasting ...the ...
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“PHASE II STUDY OF TOPICAL NIOSOMAL UREA GEL – AN ADJUVANT IN THE TREATMENT OF PSORIASIS” by Dr.P.K.Lakshmi, Dr.Shyamala Bhaskaran, India.
... on healthy human volunteers to check the irritation on the skin and to study its clinical effectives on psoriasis ...The human volunteer study to test the irritancy was performed by ...
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Assessment of Hematological and Biochemical parameters with extended D-Ribose ingestion
... D-ribose, a naturally occurring pentose carbohydrate, has been shown to replenish high- energy phosphates following myocardial ischemia and high intensity, repetitive exercise. Human studies have mainly involved ...
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Insulin resistance and sarcopenia: mechanistic links between common co-morbidities
... The impact of accumulation of intramyocellular lipid (IMCL) has been thoroughly studied, and there is a well- established association between IMCL and muscle IR and T2D. However, triacylglycerol, the main storage form of ...
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... in healthy human volunteers for its eff ects on skin sebum produc- tion as many of the active constituents in green tea are prompted to contain anti-sebum effects declared by a study that green tea ...
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Biodistribution and radiation dosimetry of [64Cu]copper dichloride: first-in-human study in healthy volunteers
... hCTR1: Human copper transporter 1; ICRP: International Commission on Radiological Protection; LLI: Lower large intestine; MTD: Maximum tolerated dose; OLINDA: Organ Level Internal Dose Assessment; OSEM2D: 2-D ...
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Fecal Components Modulate Human Astrovirus Infectivity in Cells and Reconstituted Intestinal Tissues
... using human stool samples from a range of ...some healthy adults may secrete neutralizing astrovirus-specific IgA, which could conceivably play a role in mediating protective ...
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Changes in microbiota during experimental human Rhinovirus infection
... uninfected volunteers. How- ever since our volunteers functioned as their own con- trols and the human microbiota during health has been shown to be relatively stable over time [37] it is likely that ...
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