Hemiplegic migraine
De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report
... Case presentation: We describe the case of a young woman (33 year old) who suffered from the age of 8 years of episodic weakness of the limbs, associated to other subjective and objective features. From aged 25, she ...
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Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal models
... Familial hemiplegic migraine (FHM) is a rare autosomal dominant form of migraine with ...common migraine with aura; however, they share similar symptoms (Table 2, [22]) including visual, ...
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Psychotic aura symptoms in familial hemiplegic migraine type 2 (ATP1A2)
... Familial hemiplegic migraine (FHM) is an autosomal dominant type of migraine with aura (MA). The diagnostic criteria require the presence of a reversible motor deficit associated with at least one ...
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Monozygotic twin sisters discordant for familial hemiplegic migraine
... Familial hemiplegic migraine is a monogenic disorder that is distinct from migraine with typical ...that hemiplegic aura is only a severe and complex form of typical ...
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Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1
... Familial hemiplegic migraine type 1 (FHM1) is an autosomal dominant subtype of migraine with aura that is associated with ...of migraine, it affects women more frequently than ...
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The genetic relationship between epilepsy and hemiplegic migraine
... other hemiplegic migraine-related genes were ...with hemiplegic migraine or hemiplegic migraine with paroxysmal kinesigenic dyskinesia (PKD), 56 and in ...
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Genetics of familial hemiplegic migraine
... One important issue is the high clinical variability observed within given HM families having the same muta- tion. This variability concerns both episodic symptoms (hemiplegic migraine attacks) and ...
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Neuropsychologic phenotypes in familial hemiplegic migraine
... by migraine with and without ...of migraine aura of different types and also of migraine without ...from hemiplegic migraine attacks with an annual ...that migraine per se in the ...
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Late sodium current blocker GS967 inhibits persistent currents induced by familial hemiplegic migraine type 3 mutations of the SCN1A gene
... Familial hemiplegic migraine (FHM) is a severe form of hereditary autosomal dominant migraine with aura caused by mutations in three different genes encoding neuronal or glial ion transporting ...
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CACNA1A gene mutations in familial hemiplegic migraine
... familial hemiplegic migraine (FHM) gene, CACNA1A, a few years ago ...of migraine (see ...describes migraine, the search for FHM genes, the characterisation ...
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Deciphering migraine
... Migraine is an episodic headache disorder affecting as many as 10% of people worldwide. Familial hemiplegic migraine (FHM) is an autosomal dominant subtype of severe migraine accompanied by ...
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Genetics of migraine: Insights into the molecular basis of migraine disorders
... typical migraine mapped to a particular genomic region, but for which causal genes are not yet identified, support this ...to migraine susceptibility: this avenue has not been well explored in ...
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Prophylatic treatment of migraine and migraine clinical variants with topiramate: an update
... baseline migraine days, treatment discontinuation, treatment response (ie, 75%, 50% to 74%, and 50% reduction in migraine frequency), hours of disability, cost of preventive therapy, cost of acute ...
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Migraine progression in subgroups of migraine based on comorbiditiesResults of the CaMEO Study
... of migraine will most certainly be an iterative process; this analysis forms an important early step in identification of homogeneous subclasses of ...of migraine severity and other potential confounders ...
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Vestibular Migraine. (Also known as Migraine Associated Vertigo, or MAV)
... induced lateral nystagmus is commonly observed. There may also be a reduced ability to cancel or inhibit the vestibulo- ocular reflex (VOR) function, used for attaining simultaneous head and eye tracking maneuvers. These ...
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Migraine day frequency in migraine prevention: longitudinal modelling approaches
... This analysis is an assessment of the ability of longi- tudinal parametric models to capture intra- and inter-patient variability in MMD frequency over time, using data from two erenumab clinical trials as examples. ...
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GERD prevalence in migraine patients and the implication for acute migraine treatment
... a migraine attack; particularly, since the majority of OTC medication use, unlike triptan or other prescription analgesic use, goes ...various migraine and heartburn-alle- viating therapies may be critical ...
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The KATP channel in migraine pathophysiology: a novel therapeutic target for migraine
... nels exist in structures which are believed to be linked to the pathophysiology of migraine, including cerebral and meningeal arteries and the trigeminal system [19–22]. It is established that the cAMP signaling ...
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Poor sleep quality in migraine and probable migraine: a population study
... Insomnia is a prevalent sleep disorder. Individuals with insomnia may have difficulty falling asleep, staying asleep or early awakening even if enough time is given [32]. Poor sleep quality can occur as a result of ...
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Migraine – the forgotten epidemic: development of the EHF/WHA Rome Declaration on Migraine
... much migraine interfered with their lives ...of migraine in consultations with their physicians, especially if they have not had an attack for some time, and should be encouraged to keep a diary recording ...
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