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Hepatic function

Effect of Metformin Alone and Along with Pioglitazone on Hepatic Function in Diabetic Rats

Effect of Metformin Alone and Along with Pioglitazone on Hepatic Function in Diabetic Rats

... The present study was undertaken with the objective of exploring the hepatic function of MET (50 mg/kg) alone and its combination with PIO (10 mg/kg) in STZ-NIC induced diabetic rats. Recent studies have ...

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Pharmacokinetics and safety of revefenacin in subjects with impaired renal or hepatic function

<p>Pharmacokinetics and safety of revefenacin in subjects with impaired renal or hepatic function</p>

... Mild hepatic impairment was de fi ned as plasma ALT, AST, or total bilirubin levels above the upper limit of normal (ALT ≥ 44 IU/mL for males and ≥ 32 IU/mL for females; AST ≥ 40 IU/mL or total bilirubin ≥ 21 ...

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Hepatic function and the cardiometabolic syndrome

Hepatic function and the cardiometabolic syndrome

... liver function are technically very ...liver function, whether via a caloric excess or via the nature of food components (eg, fructose, many lipids, and trans fatty ...in hepatic insulin resistance ...

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Coconut oil action on the hepatic function of rats wistar submitted to the  diet hypercaloric

Coconut oil action on the hepatic function of rats wistar submitted to the diet hypercaloric

... the hepatic component of the metabolic syndrome due to its strong association with obesity, dyslipidemia, hypertension and insulin resistance index (HOMA-IR) (TAKAHASHI, 2011) may vary from steatosis to ...

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Determinants of hepatic function in liver cirrhosis in the rat  Multivariate analysis

Determinants of hepatic function in liver cirrhosis in the rat Multivariate analysis

... We investigated the determinants of hepatic clearance functions in a rat model of liver cirrhosis induced by phenobarbital/CCl4. Aminopyrine N-demethylation (ABT), galactose elimination (GBT), and serum bile acids ...

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Clinical research on liver reserve function by 13C-phenylalanine breath test in aged patients with chronic liver diseases

Clinical research on liver reserve function by 13C-phenylalanine breath test in aged patients with chronic liver diseases

... within the liver and a reduced oxidation might be used as a marker for hepatocellular dysfunction [14]. Our study also demonstrated that the PheBT can be used as a non- invasive assay to evaluate hepatic ...

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Effects of N-acetylcysteine (NAC) supplementation in resuscitation fluids on renal microcirculatory oxygenation, inflammation, and function in a rat model of endotoxemia

Effects of N-acetylcysteine (NAC) supplementation in resuscitation fluids on renal microcirculatory oxygenation, inflammation, and function in a rat model of endotoxemia

... improve hepatic function [34], and enhance tissue oxygenation and cardiac function [41], whereas delayed administration adversely affected the outcomes of critically ill patients with multiple organ ...

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Original Article A multi-center clinical observation of recombinant human thrombopoietin for the treatment of sepsis-associated thrombocytopenia

Original Article A multi-center clinical observation of recombinant human thrombopoietin for the treatment of sepsis-associated thrombocytopenia

... France)], hepatic function, renal function and other biochemical indicators (Beckman Coulter LX20; automatic biochemical analyzer, Beckman Coulter, ...

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Verapamil favorably influences hepatic microvascular exchange and function in rats with cirrhosis of the liver

Verapamil favorably influences hepatic microvascular exchange and function in rats with cirrhosis of the liver

... The effect of the calcium channel blocking agent, verapamil, on microcirculatory patterns and hepatic function was investigated in the perfused liver of cirrhotic rats. Compared with controls, cirrhotic ...

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Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4α

Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4α

... of hepatic function and increased cell senescence and apoptosis of HCC cells, indicating that targeting undifferentiated cancer cells (especially CSCs) by PRMT5 may be a promising approach for HCC ...

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Effect of Solanum Macrocarpon Fruit on Haematology, Hepatic and Renal Function

Effect of Solanum Macrocarpon Fruit on Haematology, Hepatic and Renal Function

... At the end of the treatment period, the rats were sacrificed by making incisions at their cervical regions with sterile blades after being put to sleep in a close container with help of chloroform. Their weights were ...

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Update on argatroban for the prophylaxis and treatment of heparin-induced thrombocytopenia type II

Update on argatroban for the prophylaxis and treatment of heparin-induced thrombocytopenia type II

... Abstract: Heparin-induced thrombocytopenia (HIT) is a rare but potentially severe complication of heparin therapy that is strongly associated with venous and arterial throm- bosis (HIT and thrombosis syndrome, HITTS), ...

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Insulin Protects against Hepatic Damage Postburn

Insulin Protects against Hepatic Damage Postburn

... To examine mitochondrial and ER structure in situ, we performed transmis- sion electron microscopy of liver sections from control, burn and burn-plus-insulin treated animals. We observed a signifi- cant loss of ...

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Journal of Applied Pharmaceutical Science

Journal of Applied Pharmaceutical Science

... The hepatic antioxidant parameters; glutathione, catalase, superoxide dismutase, glutathione peroxidase, nitric oxide and malondialdehyde were ...and hepatic function enzymes; aspartate and alanine ...

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FACTOR V LEVELS IN THE NEONATAL PERIOD

FACTOR V LEVELS IN THE NEONATAL PERIOD

... that the plasma Factor V activity in the adult is an index of hepatic function.7 If one subscribes to the theory of varying de- grees of hepatic immaturity in the neonatal period, it may[r] ...

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THE SERUM PROTEINS IN PORTAL CIRRHOSIS UNDER MEDICAL MANAGEMENT  ELECTROPHORETIC STUDIES

THE SERUM PROTEINS IN PORTAL CIRRHOSIS UNDER MEDICAL MANAGEMENT ELECTROPHORETIC STUDIES

... Five patients with hepatic insufficiency and ascites were studied with serial electrophoretic analyses of the serum proteins and various tests of hepatic function during the course of me[r] ...

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... liver function and modifications in hepatic cytoarchitectrein diabetes mellitus is scanty [19] therefore; the present study investigates the effect of Lactobacillus acidophilus administration on the body ...

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A Dichotomous Key to the Species under Genus Metapenaeus Wood- Mason 1891 from Indian Water

A Dichotomous Key to the Species under Genus Metapenaeus Wood- Mason 1891 from Indian Water

... Branchiocardiac carina indistinct; telson with 3 pairs of movable lateral spines; thelycum with a median boss ………………..…..M. intermedius (Kishinouye 1900). 11. Postrostral carina ending near posterior margin of carapace; ...

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Potential effects of the combination of nicotinamide, vitamin B2 and vitamin C on oxidative-mediated hepatotoxicity induced by thioacetamide

Potential effects of the combination of nicotinamide, vitamin B2 and vitamin C on oxidative-mediated hepatotoxicity induced by thioacetamide

... Thioacetamide (TAA) is a thio-sulfur-containing com- pound, which has been frequently used in leather, motor fuel, textile, paper, food, and beverage industries since long [2]. Administration of one dose of TAA leads to ...

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Efficacy of Centella asiatica ethanolic extract on cadmium induced changes in blood haematology, hepatic and nephritic function markers in albino rats

Efficacy of Centella asiatica ethanolic extract on cadmium induced changes in blood haematology, hepatic and nephritic function markers in albino rats

... hypertensive), anti-stress and anti- epilepsy. The diverse health benefits of Centella asiatica L. (Apiaceae) has lead to the increased usage of this plant in food and beverages. It has been widely used for treatment of ...

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