Hepatic glucose production
Comparison of the direct and indirect effects of epinephrine on hepatic glucose production
... total hepatic (blood or plasma) flow calculated using the indocyanine green dye ...total hepatic blood flows during the experimental period of the control, EPI po, and EPI pe groups were 28 6 2, 27 6 3, and ...
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Hypoglycemia and impaired hepatic glucose production in mice with a deletion of the C/EBPβ gene
... on hepatic glucose production, endogenous insulin and glucagon were suppressed, and glucagon was replaced ...determine hepatic glucose production, [3- 3 H]glucose (Du ...
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Direct control of hepatic glucose production by interleukin 13 in mice
... on glucose production and disposal, and a major target of antidiabetic ...of glucose metabolism may identify new strategies to lower blood sugar ...of hepatic glucose ...to ...
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Effects of sustained swimming on hepatic glucose production of rainbow trout
... blood glucose concentration throughout sustained exercise by closely matching hepatic glucose production with peripheral glucose utilization, even though this species is generally ...
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Insulin’s direct effects on the liver dominate the control of hepatic glucose production
... inhibits glucose production through both direct and indirect effects on the liver; however, considerable controversy exists regarding the relative importance of these ...of hepatic glucose ...
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Insulin signaling is required for insulin’s direct and indirect action on hepatic glucose production
... inhibit hepatic glucose production (HGP) via suppression of gluconeogenic precursors, FFAs, and ...fasted glucose was normal, but insulin levels were elevated ...mice. Glucose infusion ...
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Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation Relation to the insulin mediated inhibition of hepatic glucose production
... plasma glucose was maintained at the basal ...muscle glucose-6-phosphate (G6P) pool derived from net glycogenolysis was estimated from the ratio of specific activities of muscle UDPG and plasma ...stimulate ...
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Evidence for an important role of glucagon in the regulation of hepatic glucose production in normal man
... (euglycemia again maintained), NSGP fell markedly but only transiently, reaching its nadir at 15 min. Thereafter, NSGP rose progressively, reaching the basal rate at 105 min. These data indicate that the induction of ...
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Direct muscarinic cholinergic inhibition of hepatic glucose production in humans
... concentration (101 +/- 8 to 75 +/- 8 mg/dl, P less than 0.05). When compared with separate clamp control studies (with placebo rather than bethanechol injection) both the rate of glucose production and the ...
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p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production
... increased hepatic glu- cose production (HGP) following Nutlin-3a treatment (Figure ...total glucose levels, we normalized the glucose level to total protein level yielding similar results ...
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The Effect of Oral Methylprednisolone Pulse on Blood Sugar
... of glucose production and stimulation of glucose utilization, which might cause diabetes mellitus or aggravate preexistent ...abnormal glucose metabolism induced by steroids may reflect both ...
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Enhancement of insulin action after oral glucose ingestion
... blood glucose and insulin values had returned to ...oral glucose loads during the 20- 120-min interval of insulin infusion, glucose infusion rates increased by 44 +/- 6% (P less than ...arterialized ...
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Insulin resistance in uremia
... plasma glucose concentration was maintained at the basal level with a variable glucose ...the glucose infusion rate is a measure of the amount of glucose taken up by the entire ...
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Mild type II diabetes markedly increases glucose cycling in the postabsorptive state and during glucose infusion irrespective of obesity
... during glucose infusion (2 mg/kg per ...between hepatic total glucose output (HTGO) (2- [3H]glucose) and hepatic glucose production (HGP) ...With glucose infusion ...
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<p>A Recent Achievement In the Discovery and Development of Novel Targets for the Treatment of Type-2 Diabetes Mellitus</p>
... including glucose-lowering agents like which suppress hepatic glucose production and increase glucose uptake, insulin secretagogues, like sulphonylureas and meglitinides, which enhance ...
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The physiological regulation of glucose flux into muscle in vivo
... of hepatic glucose production in the sedentary state (Liljenquist et ...of glucose production necessary to maintain blood glucose (Wasserman, ...of hepatic glucose ...
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Adrenergic blockade alters glucose kinetics during exercise in insulin dependent diabetics
... on glucose homeostasis during exercise in six normal subjects and in seven Type I diabetic ...plasma glucose at approximately 150 ...altered glucose production, glucose uptake, or ...
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QUERCETIN IMPROVES POSTPRANDIAL HYPERGLYCEMIA IN RATS TREATED WITH HIGH-DOSE GLUCOCORTICOID
... increasing hepatic glucose production (gluconeogenesis) (3), decreasing glucose uptake into muscle and adipose tissue (4), inhibiting insulin secretion, inducing apoptotic death of pancreatic ...
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A mathematical model of brain glucose homeostasis
... brain glucose homeostasis, glucose transport from the blood to the brain should be regulated accu- rately, according to the short-term and long-term states of blood ...brain glucose homeostasis ...
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Intraportal glucose delivery enhances the effects of hepatic glucose load on net hepatic glucose uptake in vivo
... the hepatic glucose load in the regulation of liver glucose uptake has been clearly demonstrated in in vitro systems, the relationship between the hepatic glucose load and ...
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