Hepatic sinusoidal endothelial cells
MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis
... CRC cells cultured with conditioned media that contained or did not contain exogenous MIF, we observed that the expression of CD74 and CD44 had conspicuously changed (Supplementary Figure ...CRC cells that ...
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Endotoxin and CD14 in the progression of biliary atresia
... the hepatic lobules, where Kupffer cells and sinusoidal endothelial cells were immunostained positive and the arterial and venous endothelium, bile duct epithelial cells, and ...
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Decrease of PECAM-1-gene-expression induced by proinflammatory cytokines IFN-γ and IFN-α is reversed by TGF-β in sinusoidal endothelial cells and hepatic mononuclear phagocytes
... cDNA specific for rat ICAM-1 or for β- and γ-actin. This figure shows results of five experiments from five different isolations. The lower panel shows a statistical evaluation of densitometric scans. Error bars indicate ...
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Melatonin modulates the expression of Bcl 2 family proteins in liver after thermal injury in rats
... The hepatic apoptosis related genes Bcl-2 and Bax using light immunоchistochem- istry were investigated, ...too. Hepatic TNF-α and MDA levels were increased significantly following severe ...in ...
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Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo
... liver cells play a predominant role in the pathophysiology of hepatic fibrosis has not been firmly established in ...hepatocytes, sinusoidal endothelial cells, and lipocytes from normal ...
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A Reaction Diffusion Algorithm for Segmentation of Three Dimensional Sinusoidal Networks in Rats Fed a High Fat and High Cholesterol Diet: New Insights and Evaluation
... hepatocytes, hepatic blood, and biliary ...of sinusoidal endothelial ...the sinusoidal patterns of rats fed a high-fat/high-cholesterol diet were examined; these rats exhibited pathological ...
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Hepatic uptake of a modified low molecular weight heparin in rats
... Thus, a scavenger receptor-mediated uptake of heparin by liver macrophages and sinusoidal endothelial cells might play an important role for the liver metabolism of both the tracer compo[r] ...
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Liver Sinusoidal Endothelial Cells Are a Site of Murine Cytomegalovirus Latency and Reactivation
... chymal cells, namely, the hepatocytes, and NPLCs, which in- clude LSECs, Kupffer-type macrophages, liver-specific natural killer (NK) or pit cells, and hepatic stellate cells, formerly known ...
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Advances in sepsis-associated liver dysfunction
... the hepatic response in sepsis are Kupff er cells (KCs), hepatocytes and liver sinusoidal endothelial cells ...sepsis. Hepatic failure is traditionally considered as a late ...
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Liver sinusoidal endothelial cells and liver regeneration
... unique endothelial cells, both morphologically and ...small cells, with a diameter of around ...the hepatic sinusoids. LSECs are the only mammalian endothelial cells that combine ...
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Original Article SK-Hep1: not hepatocellular carcinoma cells but a cell model for liver sinusoidal endothelial cells
... with hepatic adenocarcinoma, according to the American Type Culture Collection ...no hepatic-specific genes, including albumin and α- and γ-fibrinogen, were expressed in SK-Hep1 cells ...SK-Hep1 ...
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Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids
... NO has clearly been shown to play an important hemody- namic role in different models of hepatic microcirculatory dis- turbances. In the endotoxemic mouse, L-NMMA decreases hepatic sinusoidal ...
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Cell specific expression of hepatocyte growth factor in liver Upregulation in sinusoidal endothelial cells after carbon tetrachloride
... in hepatic regeneration induced by carbon ...in sinusoidal endothelial and Kupffer ...in endothelial cells. HGF mRNA levels rose sixfold in these cells, peaking at 6 h after ...
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Increased hepatic FDG uptake on PET/CT in hepatic sinusoidal obstructive syndrome
... by sinusoidal dilatation with peliosis, nodular regenerative hyperplasia, and fibrosis ...to endothelial cell injury and stasis of blood in peliosis may produce hepatic congestion, thereby passively ...
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Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking
... marrow endothelial cells and increased vascular ...in sinusoidal endothelial cells and the expression of 2 CXCR2 ligands, CXCL1 and CXCL2, in the bone marrow were markedly increased ...
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Antagonism of RNase L Is Required for Murine Coronavirus Replication in Kupffer Cells and Liver Sinusoidal Endothelial Cells but Not in Hepatocytes
... Kupffer cells (KC), liver sinusoidal endothelial cells (LSEC), and hepatocytes from mouse ...liver cells, and cultured them in ...parenchymal cells (the hepatocytes) and the ...
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A symphony of stem cells in Vienna – looking to the future
... In contrast to axolotls, newts and zebrafish, most adult mammalian tissues have a much more restricted regenerative potential. One exception is skeletal muscle, which harbours a resident stem cell population that can ...
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Effects of intraperitoneally injected silver nanoparticles on histological structures and blood parameters in the albino rat
... The hepatic tissue showed narrowing of the sinusoids, swollen hepatocytes with hypertrophied nucleoli, and accumulation of fat globules in the nucleoplasm and ...The hepatic sinusoids showed hypertrophied ...
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Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway
... cancer cells with high sensitivity and low sensitivity to a specific chemotherapeutic drug has been recognized as a classical method for identifying drug therapeutic ...cancer cells with strong mesenchymal ...
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Arsenic stimulated liver sinusoidal capillarization in mice requires NADPH oxidase–generated superoxide
... Arsenite-stimulated defenestration and junctional PECAM-1 expression is inhibited by tempol and gp91ds- tat peptide. Cultured SECs were preincubated with tempol (A and C) or with gp91ds-tat or scrambled-tat peptide (B ...
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