Hepatitis C virus core protein
Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor.
... Hepatitis C virus (HCV) core protein is a multifunctional ...HCV core protein as a bait to screen a human liver cDNA library in a yeast two-hybrid screening system, we ...
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Immune responses to plasmid DNA encoding the hepatitis C virus core protein.
... HCV core protein induces HCV core-specific humoral and cellular immune ...HCV core and envelope proteins have been identified in subjects with HCV-associated chronic hepatitis (13, 14), ...
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The effects of hepatitis C virus core protein on the expression of miR 122 in vitro
... anti-HCV Core antibody (Abcam) diluted 1:500, at 37°C for 2 h, followed by anti-mouse IgG conjugated to Alexa 488 (Sigma) diluted 1:500, at 37°C for 1 ...
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Modulation of the trans-suppression activity of hepatitis C virus core protein by phosphorylation.
... HCV core protein is a multifunctional protein with several functional motifs, including basic charged residues, putative nuclear localization signals and DNA binding motif, and sev- eral PKA and PKC ...
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Hepatitis C Virus Core Protein Is a Dimeric Alpha-Helical Protein Exhibiting Membrane Protein Features
... HCV core protein and comparison with GBV-B core ...GBV-B core proteins. For HCV core, amino acids repertoire at each sequence position was deduced from the CLUSTAL W multiple alignments ...
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Regulated processing of hepatitis C virus core protein is linked to subcellular localization.
... during core protein maturation, the polyprotein precursor undergoes two consecutive cleavage events, resulting in the production of two forms of core pro- tein, C173 and ...localized core ...
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Hepatitis C Virus Core Protein Interacts with Cellular Putative RNA Helicase
... HCV core protein in HCV-infected ...HCV core protein interacts with CAP-Rf in ribonu- cleoprotein particles (spliceosome or ribosome) to recruit the particles for the benefit of the ...
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Transcriptional Activation of the Interleukin-2 Promoter by Hepatitis C Virus Core Protein
... HCV C protein is required for transcrip- tional ...HCV C have revealed that the carboxy-terminal domain of the protein is not required for either transcriptional modulation of the c-myc ...
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E6AP Ubiquitin Ligase Mediates Ubiquitylation and Degradation of Hepatitis C Virus Core Protein
... etch virus protease cleavage site, and FLAG tag) (16) was fused to the N terminus of the cDNA encoding core protein of HCV NIHJ1 (genotype 1b) ...MEF-tagged core protein in mammalian ...
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Effect of Hepatitis C Virus Core Protein on the Molecular Profiling of Human B Lymphocytes
... HCV core protein from an adenoviral transfection ...HCV core protein may play a role in B-cell escape from apopto- sis and thus contribute to the develop- ment of B-cell lymphoma, and may im- ...
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Modulation of Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 by Hepatitis C Virus Core Protein
... panel). Protein expressions of MAPKAPK3, MAPKAPK3-KA, core, and actin were verified using the same cell lysates with the indicated antibodies (left, lower ...Myc-tagged core in the absence or ...
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Efficient Class II Major Histocompatibility Complex Presentation of Endogenously Synthesized Hepatitis C Virus Core Protein by Epstein-Barr Virus-Transformed B-Lymphoblastoid Cell Lines to CD4+ T Cells
... chronic hepatitis C were selected from the Kagawa Medical School Medical Center (Kagawa, Japan) based on histological diagnosis of chronic hepatitis, seropositivity for anti-HCV antibodies (detected ...
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The Native Form and Maturation Process of Hepatitis C Virus Core Protein
... HCV core protein led us to analyze whether cytoplasmic and nuclear core proteins have different ...HCV core protein. This finding and the truncated protein expression pattern in ...
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Interaction between hepatitis C virus core protein and E1 envelope protein.
... envelope protein was ex- pressed by ...envelope protein does not cross-react with our anti-core ...E1 protein was faithfully expressed in this experiment, an aliquot of the same cell lysate ...
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Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 cells.
... To elucidate the molecular status of superinfection with these two hepatitis viruses, we cotransfected the full-length or truncated version of HCV structural genes core and envelope 1 to[r] ...
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Molecular Determinants for Subcellular Localization of Hepatitis C Virus Core Protein
... full-length core protein of 191 amino acids, pCAGC191, was described previously ...fluorescent protein (GFP) with a C-terminal Myc epitope tag sequences, was prepared as ...HCV core-GFP ...
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Hepatitis C Virus Core Protein Augments Androgen Receptor-Mediated Signaling
... Hepatitis C virus (HCV) infection is frequently associated with the development of hepatocellular carcinoma (HCC), which is one of the male-dominant ...HCV core protein alone or in ...
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Biosynthesis and biochemical properties of the hepatitis C virus core protein.
... Processing of the translation products was dependent on microsomal membranes and signal recognition particle, suggesting that release of the 21-kDa core protein from the polyprotein prec[r] ...
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Chimeric hepatitis B virus core particles with parts or copies of the hepatitis C virus core protein.
... Susceptibility to digestion with proteinase K of HCV core determinants on chimeric core particlesa Conditions Undigested Digested 10 min 60 min A492 of antigenic determinants of: HCV cor[r] ...
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Genetic Analysis of the Carboxy-Terminal Region of the Hepatitis C Virus Core Protein
... the core protein is absolutely required for infectious virus production, as individual substitutions resulted in wild-type titers and a core protein fragment comprising residues 1 to ...
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