Hepatocarcinoma Cells
Original Article Canarium album extract restrains lipid excessive accumulation in hepatocarcinoma cells
... Abstract: Lipid metabolism is an important section of human body metabolism, and lipid metabolism disorder can lead to multiple diseases. Canarium album is a nature food, whose extract has been reported hepatoprotective, ...
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High co-expression of the SDF1/CXCR4 axis in hepatocarcinoma cells is regulated by AnnexinA7 in vitro and in vivo
... mouse hepatocarcinoma cells with different lymphatic metasta- sis abilities and in mouse normal liver cells in vitro and in ...cancer cells in vitro and in ...
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Selective reovirus infection of murine hepatocarcinoma cells during cell division A model of viral liver infection
... murine hepatocarcinoma cell line, Hepa 1/A1, was infected with reovirus and assayed for the presence of infectious virus or reovirus antigen in ...to hepatocarcinoma cells as indicated ...
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Nanoalumina induces apoptosis by impairing antioxidant enzyme systems in human hepatocarcinoma cells
... Abstract: Alumina nanoparticles (Al 2 O 3 NPs) are gradually used in various areas, including nanomedicine, biosensors, and electronics. The current study aimed to explore the DNA damage and cytotoxicity due to Al 2 O 3 ...
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Temporal regulation of HIF-1 and NF-κB in hypoxic hepatocarcinoma cells
... Regulations between NF-κB and HIF-1 have not been adequately addressed in previous research. Here, we report that hypoxia increased NF-κB in hepatocellular carcinoma cells. The HIF-1 protein level was rapidly ...
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Mechanisms involved in PGE2-induced transactivation of the epidermal growth factor receptor in MH1C1 hepatocarcinoma cells
... Background: It is important to understand the mechanisms by which the cells integrate signals from different receptors. Several lines of evidence implicate epidermal growth factor (EGF) receptor (EGFR) in the ...
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ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway
... of hepatocarcinoma cells, we used ...overexpressed cells decreased statistically compared to control cells in the presence or absence of docetaxel (Figure 4B and ...overexpressed cells ...
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Trimethoxy-benzaldehyde levofloxacin hydrazone inducing the growth arrest and apoptosis of human hepatocarcinoma cells
... MTT assays indicated that QNT11 inhibited the prolifer- ation of human hepatocarcinoma cells in a dose- and time-dependent manner but did not appear to disturb the proliferation of non-cancerous BMSCs. The ...
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Original Article Cellular transcriptomics: gelsolin negatively regulates the expression of apoptosis-associated genes and inhibits apoptosis in hepatocarcinoma cells
... role in the cancer progress and has the potential for providing a novel thread for cancer therapy. In current study, we demonstrate the roles of GSN on anti-apoptosis of hepatocarcinoma cells by ...
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Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models
... of hepatocarcinoma lesions, com- pared to the administration of the two drugs ...neoplastic cells to tumour necrosis factor- related apoptosis-inducing ligand (TRAIL)-mediated apop- tosis ...
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Interferon α sensitizes HBx expressing hepatocarcinoma cells to chemotherapeutic drugs through inhibition of HBx mediated NF κB activation
... the cells were treated with 1 μg/ml ADM or/and ...detached cells in the medium were collected, and the remaining adherent cells were released by ...The cells were washed with ...
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Cytotoxic activity of Thai medicinal plants against human cholangiocarcinoma, laryngeal and hepatocarcinoma cells in vitro
... Results obtained from this study indicate that 6 out of a total of 28 plants and 5 recipes (Atractylodes lancea, Kaempferia galangal, Zingiber officinal, Piper chaba, Mesua ferrea, and Pra-Sa-Prao-Yhai recipe) used in ...
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Oxidative stress contributes to cobalt oxide nanoparticles-induced cytotoxicity and DNA damage in human hepatocarcinoma cells
... NP-exposed cells along with depletion of antioxidant components suggest that oxida- tive stress might be the primary mechanism for toxicity of Co 3 O 4 NPs in HepG2 ...HepG2 cells exposed to Co 3 O 4 ...
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The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy
... Mahlavu cells to the cytotoxic effects of ...HCC cells autophagy could have a tumor protecting role when neoplastic cells are treated with Akt ...glioma cells and this protected tumor ...
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Exogenous Cx43 expression decrease cell proliferation rate in rat hepatocarcinoma cells independently of functional gap junction
... Tumor cells (rat glioma, human lung giant carcinoma and human rhabdomyosarcoma) transfected with connexin 43 cDNA recovered GJIC capacity and they showed cell growth inhibition ...transfected cells, however ...
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The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells
... Mahlavu cells were treated Figure 1: BGT226 affects cell viability and cell cycle in HCC cell ...HCC cells treated with increasing concentrations of BGT226 for 48 ...Hep3B cells were treated with ...
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Hypoxia promotes the migration and invasion of human hepatocarcinoma cells through the HIF-1α–IL-8–Akt axis
... Hypoxia plays an important role in many cancers and hypoxia-inducible factors are cru- cial mediators of the hypoxia response [14]. In cancer, intratumoral hypoxia promotes tumor aggressiveness, increasing metastasis and ...
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Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells
... HepG2 cells were stimulated with serum-free medium with and without DMSO (dilution factor: 1:1 ′ 000 ‘ 000) and serum free medium with 1% free fatty acid -BSA with and without NaOH (dilution ...
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Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties
... stem cells (MSCs) and caused signifi- cant transcriptomic alterations, and in particular, induced an inflammatory phenotype in ...tumor-promoting cells, which may provide new insights into under- standing ...
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Original Article The up-regulation of P62 levels is associated with resistance of sorafenib in hepatocarcinoma cells
... P62 (also known as SQSTM1) is a multifunc- tional stress-induced scaffold protein involved in a variety of cellular processes. Its functions are strictly regulated by a wide range of post- translational modifications. ...
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