hepatocellular carcinoma cells
Mesenchymal stem cells contribute to the chemoresistance of hepatocellular carcinoma cells in inflammatory environment by inducing autophagy
... of hepatocellular carcinoma cells To study the effect of MSCs on the development of chemoresistance in HCC cells in inflammatory environ- ment, we determined influence of chemotherapeutic ...
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Ergosterol peroxide activates Foxo3-mediated cell death signaling by inhibiting AKT and c-Myc in human hepatocellular carcinoma cells
... Our previous study showed that the oil fraction isolated from the Ganoderma spores was very powerful in inducing cancer cell death [18]. Further study found that the Ganoderma oil could induce death of cancer stem- like ...
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Original Article Chloroquine sensitizes hepatocellular carcinoma cells to chemotherapy via blocking autophagy and promoting mitochondrial dysfunction
... HepG2 cells was examined with both Terminal Deoxynucleotidyl Transferase- Mediated Deoxyuridine Triphosphate NickEnd Labeling (TUNEL) Assay and FACScan flow anal- ...HepG2 cells post treatment were digested ...
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Upregulated in Hepatitis B virus-associated hepatocellular carcinoma cells, miR-331-3p promotes proliferation of hepatocellular carcinoma cells by targeting ING5
... Hepatitis B virus (HBV) is a major risk factor for development and progression of hepatocellular carcinoma (HCC). It has been reported that viral infection can interfere with cellular microRNA (miRNA) ...
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Original Article Effect of halofuginone on the inhibition of proliferation and invasion of hepatocellular carcinoma HepG2 cell line
... ed hepatocellular carcinoma-related key signal- ing ...in hepatocellular carcinoma cells, indicating an elevated activity of the JNK signaling pathway; this suggests that tumor ...
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Sorafenib and DE605, a novel c-Met inhibitor, synergistically suppress hepatocellular carcinoma
... that hepatocellular carcinoma is a complex and heterogeneous tumor with aberrant activation of several signaling pathways, researchers have sought to target hepatocellular carcinoma with a ...
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Homeobox genes and Hepatocellular Carcinoma
... and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2. Downregulation of ZEB2-AS1 decreased tumor growth and[r] ...
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Tetraspanin in oncogenic epithelial mesenchymal transition
... tumor cells from many types of ...human hepatocellular carcinoma cells causes cellular phenotypic changes that resemble classical descriptions of epithelial-mesenchymal transition (EMT), with ...
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Anticancer Activity of Cu(II), Pd(II) and Zn(II) Complexes of Phosphonate with Glutamine Amino Acid
... against Hepatocellular carcinoma cells, the inhibition percentage was plotted against concentrations of the organic ligand (PHCB) and its metal ...
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<p>Bisdemethoxycurcumin Inhibits Hepatocellular Carcinoma Proliferation Through Akt Inactivation via CYLD-Mediated Deubiquitination</p>
... not only affected the phosphorylation of Akt but also decreased the K63-linked ubiquitination of Akt. Furthermore, our research also found that BDMC did not in fl uence the K48-linked ubiquitination of Akt, which might ...
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Knockdown of TMEM16A suppressed MAPK and inhibited cell proliferation and migration in hepatocellular carcinoma
... patients’ hepatocellular carci- noma tissues, and also analyzed the biological function of hepatocellular carcinoma cells by knockdown of TMEM16A, as well as the expression of MAPK signaling ...
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A robust twelve-gene signature for prognosis prediction of hepatocellular carcinoma
... The seven of the twelve genes were upregulated in HCC tissue and were associated with poor survival, including SPP1, KIF20A, HMMR, TTK, MAGEA6, LAPTM4B and TPX2. The SPP1 gene, located on chromosome 4 in locus 4q13.22 ...
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Original Article Lower miR-145-5p expression and its potential pathways in hepatocellular carcinoma: a bioinformatics analysis with RNA-seq and microarray data
... Abstract: Background: The aim of our study was to investigate the clinical value of expression of miR-145-5p, and clarify its potential target genes and molecular function in hepatocellular carcinoma (HCC). ...
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Screening for Hepatocellular Carcinoma
... Screening for Hepatocellular Carcinoma Screening for Hepatocellular Carcinoma I Merican, FRCp, Department of Medicine, Hospital Kuala Lurnpur, 50586 Kuala Lurnpm Hepatocellular carcinoma (HCC), a high[.] ...
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Original Article Overexpression of proteinase inhibitor 9 is associated with poor prognosis in human hepatocellular carcinoma and with proliferation and apoptosis in HepG2 cells in vitro
... HCC is the most common primary liver cancer and the third leading cause of death from cancer worldwide, accounting for 50% of cancer-related deaths. Compared with chemotherapy, surgical resection is an effective ...
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Sarcomatoid hepatocellular carcinoma (SHC): a case report
... techniques. The primary hepatic sarcoma cell is histo- logically characterized by a spindle shape, possessing a clear nucleolus and acidophilic cytoplasm, atypia, and significant mitotic attributes [5]. Sarcomatous ...
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Hypoxia-induced CCL28 promotes recruitment of regulatory T cells and tumor growth in liver cancer
... Tumor cells craft microenvironment to overcome growth disadvantages and adjust to escape the immunosurveillance during tumorigenesis and ...tumor cells. In this study, we found that hypoxia ...
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Integrated analysis of miRNA, gene, and pathway regulatory networks in hepatic cancer stem cells
... The network is an objective representation of all reg- ulatory relationships between miRNAs and genes in HCSCs. Fig. 4a, b represent the regulatory networks of miRNAs up- and down-regulated in HCSCs compared with cancer ...
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Role of 18F-FDG PET/CT in Detecting Extrahepatic Metastases in Cirrhotic Patients with Hepatocellular Carcinoma in Pre Liver Transplantation
... [17] Reinartz P, Wieres FJ, Schneider W, Schur A and Buell U (2004). Side-by-side reading of PET and CT scans in oncology: which patients might profit from integrated PET/CT?. Eur J Nucl Med Mol Imaging, 31(11): ...
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Emerging role of Toll-like receptor 4 in hepatocellular carcinoma
... TLRs play a critical role in innate immunity since they are expressed not only in innate immune cells, but also in nonimmune cells including cancer cells. Functional TLR4 expression has been linked ...
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