Hepatocellular Carcinomas
Immunohistochemical analysis of metastasising hepatocellular carcinomas in dogs
... We used MCM3 to assess the proliferative poten- tial and the degree of malignancy of the tumour and its metastases. MCM3 staining was strong in the nuclei of cells. This protein is part of the minichro- mosomal ...
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Met regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
... Identification of specific gene expression signatures characteristic of oncogenic pathways is an important step toward molecular classification of human malignancies. Aberrant activation of the Met signaling pathway is ...
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Discrimination of hepatitis C virus in liver tissues from different patients with hepatocellular carcinomas by direct nucleotide sequencing of amplified cDNA of the viral genome
... Discrimination of Hepatitis C Virus in Liver Tissues from Different Patients with Hepatocellular Carcinomas by Direct Nucleotide Sequencing of Amplified cDNA of the Viral Genome WEN-HSIA[r] ...
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Original Article Down-expression of homeobox A9promotes cancer cell invasion in human hepatocellular carcinomas
... Abstract: Metastasis is the most important contributor to the mortality ofpatients with hepatocellular carcinomas (HCCs), but the molecular basis for this is unknown. Previous studies had found that ...
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The Role of Diffusion Weighted Magnetic Resonance Imaging in the Differential Diagnosis of Hepatocellular Carcinomas and Regenerative- Dysplastic Nodules in Cirrhotic Liver
... 40 Hepatocellular carcinomas demonstrated diffusion ...the hepatocellular carcinomas, and there was a significant difference between 2 groups ...differentiate hepatocellular carcinoma ...
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Expression and biological significance of c-FLIP in human hepatocellular carcinomas
... Human HCC (hepatocellular carcinomas) is the common hepatic highly malignant tumor. Most patients, especially in China, present at diagnosis with a high stage. The etio- pathogenisis and developments of HCC ...
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Intratumoral reciprocal expression of monocarboxylate transporter 4 and glypican 3 in hepatocellular carcinomas
... Liver cancer is the leading cause of cancer death world- wide and is the second leading cause of cancer death in men [1]. As hepatocellular carcinoma (HCC) is the most common liver malignancy, the molecular ...
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Orosomucoid 2 inhibits tumor metastasis and is upregulated by CCAAT/enhancer binding protein β in hepatocellular carcinomas
... Cancer metastasis is a complex process, and the incidence of metastasis is influenced by many biological factors. Orosomucoid 2 (ORM2) is an important glycoprotein that is mainly biosynthesized and secreted by ...
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Virus induced hepatocellular carcinomas cause antigen specific local tolerance
... T cell surveillance is often effective against virus-associated tumors because of their high immunogenicity. It is not clear why surveillance occasionally fails, particularly against hepatitis B virus– or hepatitis C ...
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A transcriptome profile in hepatocellular carcinomas based on integrated analysis of microarray studies
... Hepatocellular carcinoma (HCC) is one of the most fre- quently occurring malignant tumors worldwide [1]. Risk factors of HCC are well recognized including gender, infection by hepatitis B virus or hepatitis C ...
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Three-dimensional whole-liver perfusion magnetic resonance imaging in patients with hepatocellular carcinomas and colorectal hepatic metastases
... Morgan B, Thomas AL, Drevs J, et al : Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascul[r] ...
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High hepatitis B virus load is associated with hepatocellular carcinomas development in Chinese chronic hepatitis B patients: a case control study
... for hepatocellular carcinoma with respect to hepatitis B virus genotypes B/C, specific mutations of enhancer II/core promoter/precore regions and HBV DNA ...
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Chromosomal translocation and inverted duplication associated with integrated hepatitis B virus in hepatocellular carcinomas.
... Matsubara, Genes Develop., in press, we analyzed the structures of 19 virus genomes integrated in chromosomes of human hepatomas and showed that in about half of the studied cases, the v[r] ...
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Use of a New Algorithm with an Internally Cooled Electrode for Radiofrequency Ablation of Small Hepatocellular Carcinomas
... Patients were included following institutional review board approval. Informed consent was waived in this retrospective analysis. Exclusion criteria were: (1) pres- ence of tumors >3 cm in average diameter, (2) extra- ...
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Overexpression of Abl2 predicts poor prognosis in hepatocellular carcinomas and is associated with cancer cell migration and invasion
... We also performed an in vitro experiment to validate the effect of Abl2 gene silencing on the migration and invasion abilities of human liver cancer HepG2 cells.. Results: It has been [r] ...
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Analysis of integrated ground squirrel hepatitis virus and flanking host DNA in two hepatocellular carcinomas.
... The left end of RV50 integrated DNA is located 4 bp 5291 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest We cloned the integrated ground squirrel hepatitis B virus GSHV [r] ...
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Integrative epigenomic and genomic filtering for methylation markers in hepatocellular carcinomas
... Box-plot diagrams were analyzed to compare hypermethylated genes ( CLCN1 , GRASP and TSPYL5 ) under-expressed in HCC tumor tissue, and that display no significant losses of CNV compared [r] ...
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Whole-genome sequencing of matched primary and metastatic hepatocellular carcinomas
... In addition, we identified that shared muta- tions between primary tumors and metastases were sig- nificantly enriched in the pathways of bladder cancer, pancreatic cancer, non-small cel[r] ...
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Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic response
... and hepatocellular carcinoma ...Keywords: hepatocellular carcinoma, macroautophagy, microautophagy, autophagy inhibitor, chloroquine, hydroxychloroquine, ...
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High Expression of H3K27me3 in Human Hepatocellular Carcinomas Correlates Closely with Vascular Invasion and Predicts Worse Prognosis in Patients
... esophageal carcinomas, however, we and other groups found that high ex- pression of H3K27me3 was positively as- sociated with high invasiveness and/or poor survival ...
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