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Her -2

HER 2 therapy  HER 2/neu diagnostics in breast cancer

HER 2 therapy HER 2/neu diagnostics in breast cancer

... circulating HER-2/neu ...serum HER-2/neu test reported that all individuals tested, both normal (male and female) and cancer patients, had some level of circulating serum HER-2/ ...

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Enhanced immuno detection of shed extracellular domain of HER 2/neu

Enhanced immuno detection of shed extracellular domain of HER 2/neu

... sECD-HER 2/neu protein greater than 15 ng/ml were indicative of the potential presence and the associated progression of primary tu- mors to metastatic breast cancer ...of HER-2/neu oncogene ...

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HER2 therapy  Small molecule HER 2 tyrosine kinase inhibitors

HER2 therapy Small molecule HER 2 tyrosine kinase inhibitors

... unknown, HER-2 appears to serve as a survival factor for cardiac myocytes ...targeting HER-2, might also have cardiotoxic ...relapsed HER-2 positive breast cancer previously ...

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Update on HER 2 as a target for cancer therapy: Herceptin in the clinical setting

Update on HER 2 as a target for cancer therapy: Herceptin in the clinical setting

... of HER-2 status ...of HER-2-posi- tive and HER-2-negative patients and to make compar- isons of response rate according to different assay ...were HER- 2-positive ...

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A correlation study of the expression of HA-CD44st and HER-2 in breast cancer

A correlation study of the expression of HA-CD44st and HER-2 in breast cancer

... were expressed as mean ± SD. One-way analysis of variance (ANOVA) was used to analyze the difference between the transfection groups and the negative control group. One-way ANOVA was used to compare the means of multiple ...

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Analysis in Carcinoma Stomach Her-2/neu Positivity by Immuno-histochemistry

Analysis in Carcinoma Stomach Her-2/neu Positivity by Immuno-histochemistry

... The Her-2 protein (p185, Her-2/neu, ErbB-2) has a molecular weight of 185- KDa transmembrane tyrosine kinase receptor and belongs to the family of EGFRs ...

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Effects of ectopic HER-2/neu gene expression on the COX-2/PGE2/P450arom signaling pathway in endometrial carcinoma cells: HER-2/neu gene expression in endometrial carcinoma cells

Effects of ectopic HER-2/neu gene expression on the COX-2/PGE2/P450arom signaling pathway in endometrial carcinoma cells: HER-2/neu gene expression in endometrial carcinoma cells

... on HER-2/neu cDNA se- quence obtained from ...instructions. HER-2/neu cDNA was reverse-transcribed using the One Step RNA PCR Kit (TaKaRa) according to the manufacturer’s recom- ...

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Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells

Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells

... in HER-2-overexpressing cell lines are ...of HER-2-overexpressing human breast cancer cell ...for HER- 2 inhibitory activity and the optimal AE concentration (Figure ...

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Protein tyrosine phosphatase SHP-1 sensitizes EGFR/HER-2 positive breast cancer cells to trastuzumab through modulating phosphorylation of EGFR and HER-2

Protein tyrosine phosphatase SHP-1 sensitizes EGFR/HER-2 positive breast cancer cells to trastuzumab through modulating phosphorylation of EGFR and HER-2

... The HER-2 overexpressed human breast cancer SKBr-3 cells were cultured in medium containing 5 μ g/mL trastu- zumab continuously for 6 months, which resulting in the acquisition of trastuzumab ...and ...

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Clinical implications of the coexpression of SRC1 and NANOG in HER-2-overexpressing breast cancers

Clinical implications of the coexpression of SRC1 and NANOG in HER-2-overexpressing breast cancers

... to HER-2 expression, but they did not test the correlation between SRC1 and Ki-67, which indi- cated that SRC1 was related not only to the HER-2 expres- sion status but also to the ...

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Original Article Neurotrophin-3 upregulates HER-2 to promote the growth of brain metastasis from colorectal cancer

Original Article Neurotrophin-3 upregulates HER-2 to promote the growth of brain metastasis from colorectal cancer

... between HER-2 expression and metastasis, especially BM, there was no apparent relation- ship between the position of the primary lesion (colon or rectum) and that of the ...size. HER-2, NT-3, ...

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HER-2/Neu over-expression in invasive Bladder Cancer in Sudanese Patients

HER-2/Neu over-expression in invasive Bladder Cancer in Sudanese Patients

... al. Her-2/neu overexpression in muscle-invasive urothelial carcinoma of the bladder: prognostic significance and comparative analysis in primary and metastatic ...

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Dendrimer antibody conjugate to target and image HER-2 overexpressing cancer cells

Dendrimer antibody conjugate to target and image HER-2 overexpressing cancer cells

... anti HER- 2-monoclonal antibody (Herceptin), DOTA-Gd, and Alexa Fluor 647 (AF647) dye, as well as entrap AuNPs to prepare the multifunctional conjugate Au-G5-Gd- Herceptin-AF647, ...overexpressing ...

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Correlation of ER, PR and Her-2/Neu with Histological Variants of Breast Carcinoma.

Correlation of ER, PR and Her-2/Neu with Histological Variants of Breast Carcinoma.

... This is to certify that the dissertation entitled “CORRELATION OF ER, PR AND HER-2/neu WITH HISTOLOGICAL VARIANTS OF BREAST CARCINOMA” is a record of bonafide work done by DR. R.D. Puvitha, Post graduate ...

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Aberrant miRNAs expressed in HER-2 negative breast cancers patient

Aberrant miRNAs expressed in HER-2 negative breast cancers patient

... The Cancer Genome Atlas (TCGA) is a large database of sequencing results generated from studies involving genome analysis in a rigorous and consistent manner [27]. This allowed us to perform a direct comparison between ...

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HER 2 neu Expression in Colorectal Adenocarcinoma and Its Correlation with Clinicopathologic Variables

HER 2 neu Expression in Colorectal Adenocarcinoma and Its Correlation with Clinicopathologic Variables

... This is to certify that the dissertation entitled “HER 2 neu expression in colorectal adenocarcinoma and its correlation with clinicopathologic variables” is a record of bonafide work done by Dr.N.VANI in ...

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The Effect of Neoadjuvant Chemotherapy on ER, PR and HER 2 Expression in Breast Cancer

The Effect of Neoadjuvant Chemotherapy on ER, PR and HER 2 Expression in Breast Cancer

... and HER-2 in breast cancer tissues before and after neoadjuvant ...(+++); 2) 20% - 50% of infiltrating cancer cells were labeled with nuc- lear staining (++); 3) 1% - 20% of invasive cancer cells are ...

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Cancer biomarker HER-2/neu in breast cancer in Indian women

Cancer biomarker HER-2/neu in breast cancer in Indian women

... serum HER-2/neu levels, menopausal status and stage of ...serum HER-2/neu levels between patients with different age groups, node status and hormone receptor (ER, PgR) ...serum ...

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Immunization with a HER 2/neu helper peptide vaccine generates HER 2/neu CD8 T cell immunity in cancer patients

Immunization with a HER 2/neu helper peptide vaccine generates HER 2/neu CD8 T cell immunity in cancer patients

... and HER-2/neu peptides, p369-384, KIFGSLAFLPESFDGDPA (21), p688-703, RRL- LQETELVEPLTPS (21), p971-984, ELVSEFSRMARD- PQ (21), p369-377, KIFGSLAFL (6), p689-697, RLLQETELV (7), and p971-979, ELVSEFSRM ...

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HER 2 NEU and KI67 expression as immunolocalisation in colorectal carcinoma

HER 2 NEU and KI67 expression as immunolocalisation in colorectal carcinoma

... I solemnly declare that this dissertation titled “ HER 2 NEU AND KI67 EXPRESSION AS IMMUNOLOCALISATION IN COLORECTAL CARCINOMA ” submitted by me for the degree of M.D, is the record work carried out by me ...

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