HER2/neu
Hunk is required for HER2/neu induced mammary tumorigenesis
... in HER2/neu-induced mouse mammary tumor cell lines, that Hunk is overexpressed in HER2/neu-positive human breast can- cers, that HER2/neu activation rapidly upregulates Hunk in ...
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Suppression of Her2/Neu mammary tumor development in mda- 7/IL-24 transgenic mice
... on Her2/Neu-induced mammary tumors, in which the RAS pathway is ...with Her2/ Neu transgenic ...of Her2/Neu tumor cells isolated from triple compound transgenic mice that had not ...
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Study of prevalence of prognostic and predictive immunohistochemical markers er, PR and Her2/neu and their correlation with age in cases of female carcinoma breast in Bihar (Northern India)
... in Her2/neu positive carcinoma breast, Her2/neu diagnostics has now become mandatory with immunohistochemistry being the primary test followed by FISH (Fluorescent In Situ Hybridization) in ...
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Expression of anaplastic lymphokinase and HER2/neu immunostaining in patients with breast carcinoma
... Methods: This is a cross sectional multicenter study carried out from October 2016 to March 2017. A total of 140 subjects having breast carcinoma by using non-probability purposive sampling technique were selected. After ...
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Systematic assessment of HER2/neu in gynecologic neoplasms, an institutional experience
... the HER2/neu were selected for this ...to HER2/neu gene. Routinely, the HER2 tests by IHC and/or FISH are not performed on all gynecological neoplasms in our medical ...
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Expression of Her2/neu receptor in carcinoma gallbladder correlates significantly with advanced tumor stage
... of Her2/neu is associated with increased disease recurrence and worse prognosis in many ...correlate Her2/neu positivity with the histopathological features in carcinoma ...for ...
6
Prognostic Implications of ER, PR and HER2/Neu Protein Expression in a Cohort of Breast Carcinoma
... were HER2/neu ...the HER2/neu positivity in node positive and node negative groups ...and HER2 as a predictive factor for response to ...
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HER2/neu-directed therapy for biliary tract cancer
... Other HER2-directed therapies were lapati- nib and ...a HER2/neu mutation V777L. All other cases had HER2/neu amplifi- cation or ...
9
Interleukin 15 is required for immunosurveillance and immunoprevention of HER2/neu driven mammary carcinogenesis
... in HER2/neu-transgenic mice ...rat HER2/neu (NeuT mice) with an interleukin-12 (IL-12)- adjuvanted allogeneic HER2/neu-expressing cell vaccine gave an effective and long-lasting ...
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Notch promotes recurrence of dormant tumor cells following HER2/neu targeted therapy
... of HER2/ neu-driven primary tumors (37, 38, 50–53), neither genetic nor pharmacologic inhibition of Notch signaling prevented primary tumor formation or suppressed the growth of ...
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Evaluation of Expression of Her2/neu in Gastric Cancer and Its Significance as a Prognostic Factor in Gastric Adenocarcinoma
... for HER2/neu and tumour ...of HER2/neu positivity in OGJ & corpus cancer than antral-pylorus cancer ...of HER2/neu ranges from 24% to 12% for tumours located at the gastro ...
163
Determining the Role of Autophagy in HER2/neu-Induced Mammary Tumor Dormancy and Recurrence
... The inhibition of autophagy as a strategy to treat patients with various types of cancer is currently being tested in many clinical trials. However, determining the multiple roles of autophagy in malignant pathogenesis ...
194
Role of HER2 / neu expression in colorectal carcinomas and its correlation with histological grades
... cells. HER2 receptors are expressed in low levels on the surface of ...shows HER2/neu overexpression and its ...of HER2/neu in tumours of colorectal region varies from 0% to ...
143
Synthesis of Gemcitabine (C4 amide) [anti HER2/neu] Utilizing a UV Photoactivated Gemcitabine Intermediate: Cytotoxic Anti Neoplastic Activity against Chemotherapeutic Resistant Mammary Adenocarcinoma SKBr 3
... HER2/neu] in order to increase the gemcitabine mo- lar-incorporation-index. Examples in this regard include the application of gemcitabine and the covalent bond forming reagents at higher molar ...
23
HER2/neu immunohistochemical expression in gastric carcinoma
... the HER2/neu protein immunohistochemical expression in gastric cancer from biopsies and surgical resection specimens and to evaluate their correlation with histopathological ...
8
Clinical significance of Akt and HER2/neu overexpression in African American and Latina women with breast cancer
... in HER2/neu-overex- pressing breast tumors resistant to ...with HER2/neu-positive breast ...in HER2/ neu-overexpressing breast ...
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Original Article Immunohistochemical results of HER2/neu protein expression assessed by rabbit monoclonal antibodies SP3 and 4B5 in colorectal carcinomas
... treat HER2/neu positive breast and gastric ...evaluating HER2/neu expression in colorectal carcinomas by immunohistochemi- cal ...and HER2/neu ...
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Prognostic relevance of HER2/neu in acute lymphoblastic leukemia and induction of NK cell reactivity against primary ALL blasts by trastuzumab
... kinase HER2/neu (c-erb-B2) was originally associated with a deleterious prognosis due to its involvement in oncogenic transformation and metastatic potential ...ALL, HER2/neu is expressed in ...
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Evaluation of HER2/neu Expression in Carcinoma Cervix
... HER-2/neu over-expression or mutation results in quantitative and qualitative alteration in the membrane proteins which is the basis of its detection. [83],[84] Even though clinical correlation had not been ...
160
Clinicopathological study of benign and malignant ovarian tumours and the role of HER2/neu and ER expression in these tumours
... and HER2/neu expression with tumor type, tumor grade, prognosis and clinico-pathologic ...of HER2/neu and ER in various ovarian tumors with special reference to surface epithelial ...
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