Herpes Simplex Virus-2
The Herpes Simplex Virus 2 Virion-Associated Ribonuclease vhs Interferes with Stress Granule Formation
... a virus carrying a repair of this mutation ( ⌬ ...UL41 virus and that full- length vhs was produced in cells infected with ⌬UL41Rep virus ...⌬UL41 virus, low MOIs FIG 5 Recombinant ...
13
Inhibition of Curcumin Treated Herpes Simplex Virus 1 and 2 in Vero Cells
... curcumin-treated Herpes simplex virus-1 (HSV-1) and Herpes simplex virus-2 (HSV-2) virions in cultured Vero ...
12
Pangaea and the Out-of-Africa Model of Varicella-Zoster Virus Evolution and Phylogeography
... cella virus is Old World simian varicella virus ...FIG 2 Phylogenetic tree for the family ...HSV-1, herpes simplex virus 1; HSV-2, herpes simplex ...
8
Herpes simplex virus type 2 infection triggers AP 1 transcription activity through TLR4 signaling in genital epithelial cells
... Functional TLR4 are located on the surface of cell mem- brane for sensing extracellular stimuli, such as bacteria LPS. We then extracted total proteins from the membrane or cytoplasm of U937 cells (human leukemic ...
14
The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathways
... apoptotic genes, including genes encoding members of the cellular FLICE-inhibitory protein (cFILP) family [25], genes of the anti-apoptotic Bcl-2 family [26, 27], and genes of the inhibitor of apoptosis protein ...
8
Fine structure analysis of type-specific and type-common antigenic sites of herpes simplex virus glycoprotein D.
... A region common to herpes simplex virus type 1 and 2 gD amino acid residues 11 to 19 and two sites specific for herpes simplex virus type 2 gD one determined by proline at position 7, th[r] ...
5
Human astrovirus infection associated with encephalitis in an immunocompetent child: a case report
... for herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), enteroviruses, and Epstein–Barr ...
5
The First Immunoglobulin-Like Domain of HveC Is Sufficient To Bind Herpes Simplex Virus gD with Full Affinity, While the Third Domain Is Involved in Oligomerization of HveC
... The human herpesvirus entry mediator C (HveC/PRR1) is a member of the immunoglobulin family used as a cellular receptor by the alphaherpesviruses herpes simplex virus (HSV), pseudorabies ...
11
Incorporation of the Green Fluorescent Protein into the Herpes Simplex Virus Type 1 Capsid
... ment of KOS DNA (lane 1); this fragment exhibited a de- creased mobility in K26GFP-1 (lane 2) and K26GFP-2 (lane 3) DNA due to the insertion of the 716-bp GFP coding sequence. In the case of the digestion ...
6
Herpes Simplex Virus gD and Virions Accumulate in Endosomes by Mannose 6-Phosphate-Dependent and -Independent Mechanisms
... Substantial fractions of both soluble and membrane-bound forms of gD, expressed with Ad vectors or in HSV-infected cells, were found in late endosomes containing the 275-kDa MPR and in early endosomes containing the ...
10
Epigenetic Repression of Herpes Simplex Virus Infection by the Nucleosome Remodeler CHD3
... Depletion of CHD3 but not the highly related CHD4 nucleo- some remodeler enhances HSV IE gene expression.The family of CHD remodelers consists of nine related members that share do- mains involved in chromatin ...
7
The Interaction between the Major Capsid Protein and the Smallest Capsid Protein of Human Cytomegalovirus Is Dependent on Two Linear Sequences in the Smallest Capsid Protein
... of herpes simplex virus type 1 (HSV-1) have indicated that the mature virion capsid of this virus is composed primarily of four viral proteins (5, 10, 12, 13, 16, 19, ...from ...
6
Functional Analysis of the Triplex Proteins (VP19C and VP23) of Herpes Simplex Virus Type 1
... The most frequent amino acid insertions were CLNXX, LFKXX, and VFKXX. In addition, insertions MFKXX and FKQXX were detected in some of the transpositions (Tables 1 and 2). The transprimer and restriction enzyme ...
12
Mechanisms of expression of herpes simplex virus-common surface antigens in clonal cells of a herpes simplex virus type 2-transformed line.
... 420-429 0022-538X/81/050420-10$02.00/0 Mechanisms of Expression of Herpes Simplex Virus-Common Surface Antigens in Clonal Cells of a Herpes Simplex Virus Type 2-Transformed Line KATSUICH[r] ...
10
Subassemblies and Asymmetry in Assembly of Herpes Simplex Virus Procapsid
... As the procapsid matures, the triplexes change their interac- tions but not their shape. Despite the many maturation-related behaviors that it shares with phages, there is no overall expansion of the HSV-1 procapsid. In ...
11
Herpes simplex virus infects most cell types in vitro: clues to its success
... Although gB does not promote membrane fusion by itself, its crystal structure reveals that gB share some properties with other class I and class II fusion proteins. gB belongs to a newly defined class of fusogens: class ...
11
The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane
... To discern between hypotheses 2 and 3, we then considered the gB FP averages. Specifically, our data could not reconcile the gB(470Y) average, seen toward the center of gB and facing outward (Fig. 4), with ...
18
Genetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity.
... Characterization of an aphidicolin-resistant mutant of herpes simplex virus type 2 which induces an altered viral DNA polymerase.. Drug-resistant mutants of herpes simplex virus type 2 w[r] ...
11
Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation in Mice
... With the recent findings of HSV DNA in the CNS of pa- tients dying without encephalitis (2, 43, 68), it became impor- tant to determine whether i.c. injection of G207 might lead to reactivation of or recombination ...
10
Identification and typing of herpes simplex virus by enzyme immunoassay with monoclonal antibodies
... Typing of clinical herpes simplex virus isolates with mouse monoclonal antibodies to herpes simplex virus types 1 and 2: comparison with type-specific rabbit antisera and restriction end[r] ...
5