Herpes Simplex Virus Type 1 and Type 2
Herpes simplex virus infects most cell types in vitro: clues to its success
... HSV-2: Herpes simplex virus type-1 and type-2; HveA: herpesvirus entry mediator A; HveB: herpesvirus entry mediator B; HveC: herpesvirus entry mediator C; HVEM: ...
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Determination of herpes simplex virus type specific antibodies by enzyme linked immunosorbent assay
... We determined type-specific antibodies to herpes simplex virus type 1 HSV-1 and type 2 HSV-2 by an indirect enzyme-linked immunosorbent assay, using as antigens HSV-1 glycoprotein gC-1 a[r] ...
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Human astrovirus infection associated with encephalitis in an immunocompetent child: a case report
... for herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), enteroviruses, and Epstein–Barr ...
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Characterization of herpes simplex virus type 2 transcription during latent infection of mouse trigeminal ganglia.
... RNA from an immediate early region of the type 1 herpes simplex virus genome is present in the trigeminal ganglia of latently infected mice.. Latent herpes simplex virus type 1 transcrip[r] ...
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Fine structure analysis of type-specific and type-common antigenic sites of herpes simplex virus glycoprotein D.
... A region common to herpes simplex virus type 1 and 2 gD amino acid residues 11 to 19 and two sites specific for herpes simplex virus type 2 gD one determined by proline at position 7, th[r] ...
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Amplification of Reiterated Sequences of Herpes Simplex Virus Type 1 (HSV 1) Genome To Discriminate between Clinical HSV 1 Isolates
... of 1 M, and each deoxynucleoside triphosphate, including equimolar amounts of dGTP and 7-deaza-2⬘-dGTP (Boehringer Mannheim, Mannheim, Germany), at a concentration of 200 ...Table 1), and primer ...
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Novel Class of Thiourea Compounds That Inhibit Herpes Simplex Virus Type 1 DNA Cleavage and Encapsidation: Resistance Maps to the UL6 Gene
... The level of similarity between HSV-1 UL6 (strain Patton) and its HCMV homologue UL104 (strain AD169) is 21% (data not shown). This might indicate that the actual function of these proteins is conserved but that ...
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A Pre-Immediate-Early Role for Tegument ICP0 in the Proteasome-Dependent Entry of Herpes Simplex Virus
... Reduced capsid transport to the nucleus in the absence of tegument ICP0. To begin to address the impact of virion ICP0 on HSV entry, we analyzed HSVs bearing mutations in the ICP0 gene (Table 1). Viruses with ICP0 ...
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Herpes simplex virus type 2 infection triggers AP 1 transcription activity through TLR4 signaling in genital epithelial cells
... Fig. 2 a-b, HSV-2-infection enhance TLR4 mRNA transcription in a time-dependent manner in both cell ...against herpes viral DNA polymer- ases, and it could suppress viral productive cycle, but no or ...
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Effect of Apolipoprotein E on the Cerebral Load of Latent Herpes Simplex Virus Type 1 DNA
... of virus suspension as previously described ...subsides 2 weeks after inoc- ulation and all HSV-1 present is in a latent state by 4 weeks after inoculation (33), the mice were sacrificed at 37 days ...
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A Gene Capable of Blocking Apoptosis Can Substitute for the Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene and Restore Wild-Type Reactivation Levels
... stable 2-kb LAT may encode a protein (5, 38), this protein is unlikely to play an important role in reactivation since it is located outside the region of LAT to which the reactivation function maps in rabbits ...
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Extracellular vesicles during Herpes Simplex Virus type 1 infection: an inquire
... the virus expresses a subset of immediate- early, early and latent genes, including viral homologues of the anti-apoptotic Bcl-2 family members, the viral interleukin (vIL-10) and BZLF1 that secure the ...
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Identification and typing of herpes simplex virus by enzyme immunoassay with monoclonal antibodies
... Typing of clinical herpes simplex virus isolates with mouse monoclonal antibodies to herpes simplex virus types 1 and 2: comparison with type-specific rabbit antisera and restriction end[r] ...
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Quantitation of herpes simplex virus type 1 DNA and latency-associated transcripts in rabbit trigeminal ganglia demonstrates a stable reservoir of viral nucleic acids during latency.
... of herpes simplex virus type 1 (HSV-1) DNA and latency- associated transcripts (LAT) in the latently infected rabbit trigeminal ...17Syn 1 strain of ...
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Deciphering the epidemic synergy of herpes simplex virus type 2 (HSV 2) on human immunodeficiency virus type 1 (HIV 1) infection among women in sub Saharan Africa
... (Table 1). Table 1 presents participants’ socio- demographic, risk behavior and medical/biological char- acteristics by their HSV-2 and HIV-1 infection ...
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Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation in Mice
... made 1 mm rostral of the bregma and 2 mm right of midline, and a beveled 29-gauge Hamilton needle was used to inoculate 2 to 5 l of virus at a depth of 2 mm from the skull surface over ...
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Interaction of herpes simplex virus glycoprotein gC with mammalian cell surface molecules.
... Truncated gC binds to cell surface HSPG. We demonstrated that truncated gC binds specifically to HSPG, employing three methods used previously to study the interaction of HSV viri- ons with the cell surface. First, HSV ...
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Syncytium-inducing mutations localize to two discrete regions within the cytoplasmic domain of herpes simplex virus type 1 glycoprotein B.
... Nucleotide sequence of a region of the herpes simplex virus type 1 gB glycoprotein gene: mutations affecting rate of virus entry and cell fusion.. The active inhibition of herpes simplex[r] ...
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Parzefall, Birgit (2010): PCR-based investigation of the presence of herpesvirus in the peripheral vestibular system in cats and dogs. Dissertation, LMU München: Tierärztliche Fakultät
... latent virus) or latent virus 21 ...lytic virus cycle with expression of the entire set of viral proteins 21; 107 ...latent virus may be induced by different types of distress and causes a ...
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The herpes simplex virus immediate-early protein, ICP4, is required to potentiate replication of human immunodeficiency virus in CD4+ lymphocytes.
... Deletion mutants in the gene encoding the herpes simplex virus type I immediate-early protein ICPO exhibit impaired growth in cell culture.. The herpes simplex virus type 1 alpha protein[r] ...
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