Heterochromatin protein
The Yeast Heterochromatin Protein Sir3 Experienced Functional Changes in the AAA+ Domain After Gene Duplication and Subfunctionalization
... the protein is no longer constrained to achieve multiple ...yeast heterochromatin protein Sir3, which arose by duplication from the conserved DNA replication protein ...for ...
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Expression and chromatin structures of cellulolytic enzyme gene regulated by heterochromatin protein 1
... Cellulolytic enzyme production is tightly controlled at the transcriptional level in fungi. Several transcrip- tional activators (i.e., orthologous XlnR/Xyr1 and ClrB/ Clr2) [6, 7] and repressors (i.e., orthologous ...
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Bi-phasic expression of Heterochromatin Protein 1 (HP1) during breast cancer progression: Potential roles of HP1 and chromatin structure in tumorigenesis
... BRCA1 has diverse molecular functions, including transcription regulation and cell cycle control. Notably, BRCA1 is critical for maintaining genomic integrity in response to DNA damage (4). BRCA1 promotes homologous ...
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Differential Effects of Heterochromatin Protein 1 Isoforms on Mitotic Chromosome Distribution and Growth in Dictyostelium discoideum
... Heterochromatin protein 1 (HP1) is a well-characterized heterochromatin component conserved from fission yeast to ...fluorescent protein (GFP) fusion proteins in one major cluster at the ...
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A balancing act: heterochromatin protein 1a and the Polycomb group coordinate their levels to silence chromatin in Drosophila
... constitutive heterochromatin is formed, HP1a is also recruited to these sites (blue circles), establishing the normal euchromatin promoter/heterochromatin distributions of PcG/trxG proteins and HP1a and ...
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Recruitment of Tat to Heterochromatin Protein HP1 via Interaction with CTIP2 Inhibits Human Immunodeficiency Virus Type 1 Replication in Microglial Cells
... CTIP1 protein appears unable to form such distinct structures, to alter the localization of Tat, and to affect Tat ...leukemia protein recruits the CREB- binding protein to subnuclear promyelocytic ...
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Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells
... RNA-processing protein category also led us to wonder whether this category of proteins could be involved in the silencing function of HP1β in differentiated ...by heterochromatin, we propose that HP1β and ...
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Heterochromatin protein 1 gamma and IiB kinase alpha interdependence during tumour necrosis factor gene transcription elongation in activated macrophages
... bromodomain-containing protein 4 (Brd4) is triggered by a cascade of events initiated by histone H3 Serine 10 (H3S10) phosphorylation and leading to histone H4 acetylation ...
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Evolutionary Analysis of Heterochromatin Protein Compatibility by Interspecies Complementation in Saccharomyces
... In this study, we used genetic screens and interspecies complementation assays to test whether Sir-protein-based transcriptional silencing was conserved between two Saccharo- myces species separated by DNA ...
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Heterochromatin Protein 1 Is Required for the Normal Expression of Two Heterochromatin Genes in Drosophila
... Saunders, R. D. C., M. C. Avides, T. Howard, C. Gonzalez and D. M. Warner, T. S., D. A. Sinclair, K. A. Fitzpatrick, M. Singh, R. H. Glover, 1997 The Drosophila gene abnormal spindle encodes a Devlin et al., 1998 The ...
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2019_Bregio.pdf
... of heterochromatin protein 1 (HP1) have demonstrated that modulation of this protein alters the invasive potential of breast cancer cells (Norwood et ...
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Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary
... for heterochromatin function were identified in PEV modifier screens (Reuter et ...of heterochromatin blocks, suggesting that the bound- aries between repressed and active chromatin expand and con- tract ...
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A paucity of heterochromatin at functional human neocentromeres
... centromeric heterochromatin, charac- terized by H3K9me3 and heterochromatin protein 1 (HP1) was evaluated at the BBB ...centric heterochromatin sequences present in the Affy- metrix tiling ...
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Understanding heterochromatin characterization through chromosome banding
... of heterochromatin of different organisms is one of the intriguing aspects in cytological analysis, owing to which different methods have been developed time and again to characterize ...of heterochromatin ...
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SEQUENCE OF CENTROMERE SEPARATION: ROLE OF CENTROMERIC HETEROCHROMATIN
... Thus, in animal NB-79, 25 cells showed initial or complete separation of X chromosome without Y showing any separation, in contrast to only four Y chromosomes sh[r] ...
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ROLE OF RNAi IN HETEROCHROMATIN FORMATION AND CHROMATIN REMODELLING
... of protein–protein interactions which have a key role in most biological processes, and offer attractive opportunities for therapeutic intervention (Arkin MR and Well JA, 2004) Discovery of newer ...
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Heterochromatin Controls γH2A Localization in Neurospora crassa
... with heterochromatin in ...of heterochromatin domains in wild-type Neurospora ...conserved heterochromatin component in fungi, or at least in the ...in heterochromatin in other eukaryotes as ...
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Chromosome behavior in cell differentiation: a field ripe for exploration?
... In most differ- entiated cells, heterochromatin and other condensed chromosomes as a rule are attached to the nuclear membrane, or sometimes to the nucleolus.. The t[r] ...
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A CORRELATION OF PHENOTYPIC CHANGES AND CHROMOSOMAL REARRANGEMENTS AT THE TWO ENDS OF AN INVERSION
... However, there are certain disadvantages to the use of this inversion in a precise analysis of the role of heterochromatin, since the inversion places the roughest locus i[r] ...
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Herpesviral ICP0 Protein Promotes Two Waves of Heterochromatin Removal on an Early Viral Promoter during Lytic Infection
... that heterochromatin was removed from IE gene pro- moters ...of heterochromatin association with early gene promoters has not been ...and heterochromatin modifications H3K9me3 and H3K27me3 peaked ...
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