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High Grade Glioma.

Carbon Ion Beam Reirradiation in Recurrent High-Grade Glioma

<p>Carbon Ion Beam Reirradiation in Recurrent High-Grade Glioma</p>

... recurrent glioma, the extent of resection and age at primary diagnosis were – among others - signi fi cant factors for ...recurrent high-grade glioma, multivariate analysis on OS revealed ...

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Role of dti in differentiating high grade glioma and solitary metastasis

Role of dti in differentiating high grade glioma and solitary metastasis

... differentiate glioma from metastatic disease; however, because the vasogenic edema an increased water component (13), we used peritumoral DTI to study the molecular motion of the ...and high grade ...

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Deubiquitinase USP9X deubiquitinates β-catenin and promotes high grade glioma cell growth

Deubiquitinase USP9X deubiquitinates β-catenin and promotes high grade glioma cell growth

... high grade glioma patients, and USP9X interacted with and stabilized β-catenin and activated the WNT/β-catenin signal pathway to promote glioma cells proliferation and survival in vitro and in ...

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Identification of COX5B as a novel biomarker in high-grade glioma patients

Identification of COX5B as a novel biomarker in high-grade glioma patients

... different-grade glioma tissues and to try to identify some genes associated with the tumorigenesis of ...in high-grade glioma under the condition of “Q ...the grade IV ...

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ABCG1 maintains high-grade glioma survival in vitro and in vivo

ABCG1 maintains high-grade glioma survival in vitro and in vivo

... develop high-grade gliomas [18, 19]. Moreover, derivative glioma cells from these NPcis mouse tumors exhibit bi-allelic loss of the Nf1 and Trp53 genes in addition to increased PDGFRα expression, ...

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A Simple Automated Method for Detecting Recurrence in High Grade Glioma

A Simple Automated Method for Detecting Recurrence in High Grade Glioma

... recurrent high-grade ...of high-grade glioma were ...of high-grade glioma that was amenable to focal re-irradiation (cohort ...recurrent high-grade ...

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Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma

... pediatric glioma mutation assessment was performed using publically-available matched tumor/ non-tumor genome sequencing datasets, all of which were accessed through the European Genome-phenome Archive (EGA), ...

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Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma.

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma.

... pediatric glioma mutation assessment was performed using publically-available matched tumor/ non-tumor genome sequencing datasets, all of which were accessed through the European Genome-phenome Archive (EGA), ...

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Nimotuzumab as a radiosensitizing agent in the treatment of high grade glioma: challenges and opportunities

Nimotuzumab as a radiosensitizing agent in the treatment of high grade glioma: challenges and opportunities

... Abstract: Nimotuzumab is a humanized monoclonal antibody that binds specifically to human epidermal growth factor receptor, blocking receptor activation. Evidence of its radiosensitiz- ing capacity has been widely ...

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ABBREVIATED COURSE OF RADIATION THERAPY WITH CONCURRENT TEMOZOLOMIDE FOR HIGH-GRADE GLIOMA

ABBREVIATED COURSE OF RADIATION THERAPY WITH CONCURRENT TEMOZOLOMIDE FOR HIGH-GRADE GLIOMA

... Temozolomide (TMZ), an oral alkylating agent with good CNS penetrance has been shown to improve survival with minimal hematologic toxicity when given concurrently with conventionally fractionated radiation (60 Gy) [7] . ...

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Pediatric high-grade glioma: biologically and clinically in need of new thinking.

Pediatric high-grade glioma: biologically and clinically in need of new thinking.

... High-grade gliomas in children are different from those that arise in adults. Recent collaborative molecular analy- ses of these rare cancers have revealed previously unappreciated connections among ...

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Mindbomb Homolog-1 Index in the Prognosis of High-Grade Glioma and Its Clinicopathological Correlation.

Mindbomb Homolog-1 Index in the Prognosis of High-Grade Glioma and Its Clinicopathological Correlation.

... in highgrade gliomas and its correlation with outcome and ...51 highgrade glioma tissue samples in ...with high MIB‑1 index and by correlation with ...with Grade IV ...

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Image Mining Segmentation Adaboost Glioma Prevents Progression to High Grade Glioma Accuracy(Imsaga)

Image Mining Segmentation Adaboost Glioma Prevents Progression to High Grade Glioma Accuracy(Imsaga)

... Ursula Perez; Estanislao Arana; David Moratal Et al [1] Model-based methods detect metastases due to their high degree of similarity with models representing their morphology, mainly templates. On the other hand, ...

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Single-cell transcriptome analysis of lineage diversity in high-grade glioma

Single-cell transcriptome analysis of lineage diversity in high-grade glioma

... contained a well-defined subpopulation that strongly re- sembled myelinating oligodendrocytes with specific ex- pression of multiple myelin genes including MBP , MOG, and MAG. Hence, HGGs harbor cells that resemble a ...

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High frequency of the X-chromosome inactivation in young female patients with high-grade glioma

High frequency of the X-chromosome inactivation in young female patients with high-grade glioma

... In the current study, SXCI (CR ≥ 3) frequency was determined to be as high as 23.6% in young patients (≤40 years) with gliomas, which was significantly higher than that in the corresponding control subjects ...

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Profile of nimotuzumab in the treatment of high-grade glioma

Profile of nimotuzumab in the treatment of high-grade glioma

... included grade I–II neutropenia (two cases), thrombocytopenia (two cases), lym- phopenia (one case), nausea and vomiting (three cases), and asymptomatic transaminase increase (one ...developed grade IV ...

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Extracranial metastases of high grade glioma: the clinical characteristics and mechanism

Extracranial metastases of high grade glioma: the clinical characteristics and mechanism

... In summary, the glioblastoma might undergo extracra- nial metastasis. Although we have described extracranial metastases of malignant gliomas in detail, the complex mechanism underlying metastasis remains unclear. Since ...

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High-grade glioma in elderly patients: can the oncogeriatrician help?

High-grade glioma in elderly patients: can the oncogeriatrician help?

... Isocitrate dehydrogenase 1 (IDH1) mutations have been reported to be expressed in low-grade, anaplastic glioma, and secondary glioblastoma. This mutation is associated with bet- ter clinical outcomes for ...

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Mesenchymal high grade glioma is maintained by the ID RAP1 axis

Mesenchymal high grade glioma is maintained by the ID RAP1 axis

... of glioma cells (2–6). The selective ablation of Id genes in glioma cells has allowed us to define a GIC-intrinsic role of ID proteins for the communication with the perivascular tumor ...in glioma ...

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A case of left frontal high-grade glioma diagnosed during pregnancy

A case of left frontal high-grade glioma diagnosed during pregnancy

... A 162-cm, 61.4-kg, 30-year-old, right-handed primigrav- ida was referred to our institution at 21 weeks gestation to obtain a second opinion; although, the fetus did not show signs of growth retardation, therapeutic ...

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