Hippo signaling pathway
Original Article miR-135b-5p regulates human mesenchymal stem cell osteogenic differentiation by facilitating the Hippo signaling pathway
... the Hippo signaling pathway during osteo- genesis has not been ...the Hippo signaling pathway was activated by miR-135b-5p ...the HIPPO signaling pathway, ...
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Original Article Knockdown of miR-572 suppresses cell proliferation and promotes apoptosis in renal cell carcinoma cells by targeting the NF2/Hippo signaling pathway
... of Hippo signaling in multi- ple biological processes ...via Hippo signaling in the development of Droso- phila ...activating Hippo sig- naling in the heart ...the Hippo ...
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Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway
... Taken together, we found that in vitro hAD-MSC-differentiated adipocytes could secrete exosomes which are actively taken up by breast can- cer cell line MCF7 and subsequently promote breast cancer cell MCF7 proliferation ...
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Upregulation of miR-181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathway
... The Hippo signaling pathway plays a crucial role in regulating tissue homeostasis, organ size, tumorigenesis and cancer chemoresistance when ...the Hippo core kinase cassette that consists of ...
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Potential Role of Hippo Signaling Pathway in Gastric Cancer
... the Hippo-signaling pathway, with a few kinases contrarily controlling YAP, is expanded by vari- ous diverse pathways that give info into this center cassete including cell extremity, cell to cell ...
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TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway
... of Hippo signaling pathway, was the most highly regulated by upregulation of TFAP2C, but si- lenced by downregulation of TFAP2C in CRC cells (Additional file 11: Figure ...of Hippo ...
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The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway
... the Hippo signaling ...downregulated Hippo signaling, Lats activity was unaffected by E4orf4 ...the Hippo signaling path- way (56, 100), a recent study reported B55 and A subunit ...
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<p>SRPX2 Promotes Cell Proliferation and Invasion in Osteosarcoma Through Regulating Hippo Signaling Pathway</p>
... the Hippo signal transduction pathway can inhibit OS occurrence and ...the Hippo signal transduction path- way, is overexpressed in various ...the Hippo signaling ...
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The Hippo signaling pathway: a potential therapeutic target is reversed by a Chinese patent drug in rats with diabetic retinopathy
... the Hippo signaling pathway in the progression of DR, the influence of Fufang Xuesuhangtong (XST) Capsule, a patented Chinese drug that is reported to impede DR, on the Hippo pathway ...
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The hippo signaling pathway: implications for heart regeneration and disease
... of Hippo signaling compo- nents between Drosophila and ...mammalian Hippo signaling involves the activation of a conserved kinase cascade that ultimately phosphorylates the transcription ...
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PubMedCentral-PMC5035397.pdf
... the Hippo signaling pathway, which regulates organ size by modulating cell growth, proliferation and apoptosis ...the Hippo path- way components are highly conserved from Drosophila to mam- ...
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Chronic constriction injury of sciatic nerve changes circular RNA expression in rat spinal dorsal horn
... Results: circRNA microarrays showed that 469 circRNAs were differentially expressed between CCI and sham-operated rats (fold change ≥2). In all, 363 of them were significantly upregulated, and the other 106 were ...
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Original Article LATS2-mediated YAP1 phosphorylation is involved in HCC tumorigenesis
... Abstract: YAP (yes-associated protein) is a transcriptional co-activator that acts downstream of the Hippo signaling pathway and regulates multiple cellular processes, including proliferation and ...
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<p>YAP/TAZ: a promising target for squamous cell carcinoma treatment</p>
... the Hippo signaling transduction ...In Hippo-signaling pathway, YAP/TAZ is inactivated and its translocation to the nucleus is blocked via a core kinase cascade stimu- lated by a ...
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Original Article Transcriptomic analysis of dracorhodin perchlorate intervention in wound healing in SD rats
... dgehog signaling pathway, malaria, and basal cell ...estrogen signaling path- way, Hippo signaling pathway, and Cushing syn- drome, whereas downregulated genes were enriched in ...
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Regulation of Drosophila glial cell proliferation by Merlin Hippo signaling
... the Hippo pathway and its transcriptional co-activator Yorkie in controlling Drosophila glial ...Merlin-Hippo signaling pathway, whereas the upstream Hippo pathway ...
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Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling
... The Hippo signaling pathway has been identified as a tumor suppressor pathway that is conserved from Drosophila to mammals (Edgar, 2006; Pan, ...kinase Hippo (Hpo), the scaffold protein ...
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The Hippo pathway effector Yki downregulates Wg signaling to promote retinal differentiation in the Drosophila eye
... the Hippo signaling pathway have been described, including stem cell renewal and maintenance, regeneration, wound healing and axial patterning (Halder and Camargo, 2013; Yu and Guan, ...the ...
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Mst1 and Mst2 kinases: regulations and diseases
... The Hippo signaling pathway has emerged as a critical regulator for organ size ...the Hippo kinase from Drosophila, play the central roles in the Hippo pathway controlling the ...
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PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis
... the Hippo signaling pathway are mainly the following: (1) to regulate the size and growth of tissues and organs, (2) to regulate cell proliferation and apoptosis, (3) to regulate the ...
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