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HIPPOCAMPAL-NEURONS

Original Article Tanshinone IIA pretreatment attenuates oxygen-glucose deprivation induced hippocampal neurons damage

Original Article Tanshinone IIA pretreatment attenuates oxygen-glucose deprivation induced hippocampal neurons damage

... Guilin Medical University. For all experiments, we used an in vitro system of primary cultures of hippocampal neurons prepared from E18 embryonic rats (SPF experimental animal cen- ter of Guilin Medical ...

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Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells

Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells

... protected hippocampal neurons from radiation- induced damage in both cell culture and animal ...normal hippocampal neurons and not cancer cells from radiation-induced cytotoxicity both in ...

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Plasticity of hippocampal memories in humans

Plasticity of hippocampal memories in humans

... such hippocampal neurons continue to differentiate between specific elements in the environment once Halle Berry has been seen at the Eiffel Tower, how is the hippocampus able to independently represent ...

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Melatonin changes the electrical spontaneous activity of hippocampal rat neurons at different ages

Melatonin changes the electrical spontaneous activity of hippocampal rat neurons at different ages

... CA1 hippocampal neurons ...activity, neurons in CA1 region shown an increase of spontaneous firing rate after chro- nic melatonin application as it has been mentioned in vitro experiments ...

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3D Multicolor Super-Resolution Imaging Offers Improved Accuracy in Neuron Tracing

3D Multicolor Super-Resolution Imaging Offers Improved Accuracy in Neuron Tracing

... with neurons expressing either one of the two ...two-color neurons, we transfected the hippocampal neurons separately with either YFP or mCherry prior to plating using ...transfected ...

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FcγRIIb mediates amyloid β neurotoxicity and memory impairment in Alzheimer’s disease

FcγRIIb mediates amyloid β neurotoxicity and memory impairment in Alzheimer’s disease

... the hippocampal regions of the AD patients, while the level of NeuN was slightly reduced compared with normal control or mild cognitive impairment (MCI) patients (Figure 1, A and B, and Supplemental Table ...

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The generation of time in the hippocampal memory system

The generation of time in the hippocampal memory system

... different hippocampal neurons responding at discrete times, as has been observed (Eichenbaum, 2014, 2017; Howard and Eichenbaum, 2015; Kraus et ...in hippocampal neurons, representations ...

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Borna Disease Virus Glycoprotein Is Required for Viral Dissemination in Neurons

Borna Disease Virus Glycoprotein Is Required for Viral Dissemination in Neurons

... rat hippocampal neurons are highly sus- ceptible to infection with cell-free BDV ...primary hippocampal neurons. (A) Experimental setup. Primary hippocampal neurons were infected ...

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Membrane Potential Dynamics of Hippocampal Neurons During Ripples in Awake Mice

Membrane Potential Dynamics of Hippocampal Neurons During Ripples in Awake Mice

... Figure 18: SIA is associated with a hyperpolarized membrane potential and small sub- threshold fluctuations (A) The top panel shows a spectrogram of the average LFP power (z-score by frequency) triggered on transitions ...

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Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic  and antidepressant like effects

Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic and antidepressant like effects

... newborn hippocampal neurons following chronic HU210 treat- ment in adult ...newborn neurons in the dentate granule cell layer that had survived 4 weeks were stably integrated into the granule cell ...

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Clustered c Fos Activation in Rat Hippocampus at the Acquisition Stage of Appetitive Instrumental Learning

Clustered c Fos Activation in Rat Hippocampus at the Acquisition Stage of Appetitive Instrumental Learning

... [24]. Hippocampal neuronal activity plays a crucial role in establish- ment of action-outcome relationship during instrumental learning [25] ...of hippocampal neurons into synchronized ensembles ...

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Chemogenetic silencing of hippocampal neurons suppresses epileptic neural circuits

Chemogenetic silencing of hippocampal neurons suppresses epileptic neural circuits

... in hippocampal neural stem cells and also in neural stem cells in the subventricular zone that produce olfactory interneu- rons (Supplemental Figure ...of hippocampal newborn DGC neuronal activity for ...

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Reducing expression of synapse restricting protein Ephexin5 ameliorates Alzheimer’s like impairment in mice

Reducing expression of synapse restricting protein Ephexin5 ameliorates Alzheimer’s like impairment in mice

... mouse hippocampal neurons with soluble Aβ 1-42 during development, when EPHB2 is known to be active and Ephexin5 is degraded (10, ...–treated neurons as measured by immunocyto- chemistry (Figure ...

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Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

... LM22A compounds function through TrkB. (A) Survival analysis of hippocampal neurons treated with BDNF (0.7 nM) or LM22A compounds (500 nM) with or without the Trk inhibitor K252a (200 nM). For BDNF, n = 37 ...

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Norepinephrine Induces BDNF and Activates CREB and Discriminates among Protein Kinase C Isoforms in Cultured Embryonic Hippocampal Neurons

Norepinephrine Induces BDNF and Activates CREB and Discriminates among Protein Kinase C Isoforms in Cultured Embryonic Hippocampal Neurons

... cultured hippocampal neurons leads to increased expression of BDNF, phos- phorylation of CREB, activation of growth-associated protein-43 (GAP-43) and activation of PKC μ and PKC θ t538 ...

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Synergic interaction between amyloid precursor protein and neural cell adhesion molecule promotes neurite outgrowth

Synergic interaction between amyloid precursor protein and neural cell adhesion molecule promotes neurite outgrowth

... the hippocampal neurons cultured in vitro. Hippocampal neurons were isolated from APP knock-out and APP knock-in mice and seeded directly in culture plastic ...The neurons were ...

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The Subiculum: What It Does, What It Might Do, And What Neuroanatomy Has Yet To Tell Us

The Subiculum: What It Does, What It Might Do, And What Neuroanatomy Has Yet To Tell Us

... Neurophysiological depth profiles of the CA1– subiculum projection, examining excitatory postsynaptic potentials evoked in the subiculum following stimula- tion of different sites by a bipolar stimulating electrode en ...

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Relative Neurotropism of a Recombinant Rhabdovirus Expressing a Green Fluorescent Envelope Glycoprotein

Relative Neurotropism of a Recombinant Rhabdovirus Expressing a Green Fluorescent Envelope Glycoprotein

... Having shown that the recombinant VSV has a similar af- finity for brain regions previously demonstrated for the wild- type virus and a preference for developing neurons, an unan- swered question remains—why does ...

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Understanding the Chemical Basis of Neuronal Development and Communication: I  The Role of Fucose α(1 2) Galactose Carbohydrates in Neuronal Growth  II  Structure Function Analysis of Chondroitin Sulfate in the
Brain

Understanding the Chemical Basis of Neuronal Development and Communication: I The Role of Fucose α(1 2) Galactose Carbohydrates in Neuronal Growth II Structure Function Analysis of Chondroitin Sulfate in the Brain

... Dissociated neurons prepared from E18 rats were incubated with probe 2 in neurobasal ...dissociated neurons because cellular staining with probe 1 (Chapter 1) gave significant signal and thus we reasoned ...

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Fructus mume extracts alleviate cognitive impairments in 5XFAD transgenic mice

Fructus mume extracts alleviate cognitive impairments in 5XFAD transgenic mice

... One week after the behavioral experiments, 9 mice per group were decapitated and the hippocampal or cortical samples were dissected and snap-frozen. For the total protein extracts, individual tissue samples were ...

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