Histoplasma Capsulatum
A Multiplex Real Time PCR Assay for Identification of Pneumocystis jirovecii, Histoplasma capsulatum, and Cryptococcus neoformans/Cryptococcus gattii in Samples from AIDS Patients with Opportunistic Pneumonia
... H IV infection remains a threat for many people, as it is esti- mated that almost 34 million adults and children world- wide are infected with the virus, according to WHO/UNAIDS (1). Although mortality associated with ...
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Expression and Interstrain Variability of the YPS3 Gene of Histoplasma capsulatum
... numbers of tandem repeats between strains of the same and different RFLP classes suggest plasticity in the locus (Fig. 2B). Heterologous expression of the YPS3 ORF. Whereas con- centrated culture supernatants of all ...
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Apoptosis modulates protective immunity to the pathogenic fungus Histoplasma capsulatum
... H. capsulatum– infected gld/gld and TNF-a–deficient mice; concomitantly, the fungal burden exceeded that of ...H. capsulatum–immune mice with caspase inhibitors decreased apoptosis but markedly enhanced the ...
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Expression of Hygromycin Phosphotransferase Alters Virulence of Histoplasma capsulatum
... of Histoplasma capsulatum in the generation of knockout strains of ...H. capsulatum or as a marker in mutant ...H. capsulatum. Infection of mice with hph-expressing H. capsulatum yeast ...
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Antibodies to a cell surface histone like protein protect against Histoplasma capsulatum
... The dimorphic fungus Histoplasma capsulatum var. cap- sulatum (Hc) is the most prevalent cause of fungal res- piratory disease, infecting approximately 500,000 indi- viduals in the US each year (1–3). ...
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Reevaluation of Commercial Reagents for Detection of Histoplasma capsulatum Antigen in Urine
... the Histoplasma capsulatum urinary antigen (UAg) is among the most sensitive and rapid means to diagnose histo- ...(MVista) Histoplasma antigen (Ag) quantitative EIA (MiraVista Diagnostics, ...
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Extracellular Vesicle-Mediated RNA Release in Histoplasma capsulatum
... (H. capsulatum G186AR strain ABBS02 and G217B strain ...from Histoplasma capsulatum (EnsemblFungi G186AR GCA_000150115 assembly ...H. capsulatum EVs was based on results recently obtained with ...
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Localized Histoplasma capsulatum osteomyelitis of the fibula in an immunocompetent teenage boy: a case report
... Histoplasma capsulatum, a thermally dimorphic fungus, is endemic across North and Central America, particu- larly in the region of the Mississippi ...H. capsulatum only in bone is ...H. ...
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Cranial and Spinal Locations of Histoplasma Capsulatum var. duboisii in Brazzaville, Congo
... Histoplasmosis caused by Histoplasma capsulatum var. duboisii was confirmed in five of the patients aged 29-60 years old with a mean age of 42 years old, in- cluding two females and three males. The ...
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PCR Assay for Identification of Histoplasma capsulatum Based on the Nucleotide Sequence of the M Antigen
... of Histoplasma capsulatum var. capsulatum are the H and M antigens, pluripotent glycoproteins that elicit both humoral and T-cell-mediated immune ...H. capsulatum var. capsulatum ...
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Modulation of the effector function of human macrophages for Histoplasma capsulatum by HIV 1 Role of the envelope glycoprotein gp120
... We have demonstrated that monocyte-derived macrophages Mf from HIV1 individuals are deficient in their capacity to phagocytose Histoplasma capsulatum Hc yeasts, and are more permissive f[r] ...
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Antibody Binding Alters the Characteristics and Contents of Extracellular Vesicles Released by Histoplasma capsulatum
... ABSTRACT Histoplasma capsulatum produces extracellular vesicles containing virulence-associated molecules capable of modulating host machinery, benefiting the ...H. capsulatum cells with monoclonal ...
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Evaluation of an Enzyme Immunoassay for Detection of Histoplasma capsulatum Antigen from Urine Specimens
... of Histoplasma capsulatum urinary antigen (UAg) is important for the initial diagnosis of infection and for monitor- ing of patient responses to antifungal ...H. capsulatum UAg from Immuno ...
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Correlation between pathogenicity and temperature sensitivity in different strains of Histoplasma capsulatum
... of Histoplasma capsulatum (low level of virulence) with those of G184A and G222B, two more virulent strains having different levels of pathogenicity for ...
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Histoplasma capsulatum causing sinusitis: a case report in French Guiana and review of the literature
... H. capsulatum from the direct ...revealed Histoplasma capsulatum ...H. capsulatum, especially in immunocomprom- ised host and in endemic ...
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Quantitative Microplate Based Growth Assay for Determination of Antifungal Susceptibility of Histoplasma capsulatum Yeasts
... pathogen Histoplasma capsulatum, susceptibility to echinocandins differs for the yeast and the filamentous forms, which highlights the need to employ Histoplasma yeasts, not hyphae, in antifungal ...
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Phylogenetic Relationships of Varieties and Geographical Groups of the Human Pathogenic Fungus Histoplasma capsulatum Darling
... diverse Histoplasma capsulatum isolates representing the three varieties capsulatum, duboisii, and farciminosum was evaluated using partial DNA sequences of four protein coding ...H. ...
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Phagocytosis of Histoplasma capsulatum yeasts and microconidia by human cultured macrophages and alveolar macrophages Cellular cytoskeleton requirement for attachment and ingestion
... Phagocytosis of Histoplasma capsulatum Yeasts and Microconidia by Human Cultured Macrophages and Alveolar Macrophages Cellular Cytoskeleton Requirement for Attachment and Ingestion Simon[r] ...
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Surface Localization of the Yps3p Protein of Histoplasma capsulatum
... of Histoplasma capsulatum encodes a protein that is both resident in the cell wall and also released into the culture ...H. capsulatum strains that differ in ...H. capsulatum. Flow cytometric ...
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Molecular characterization of Histoplasma capsulatum isolated from an outbreak in treasure hunters
... Histoplasma capsulatum develops in bird excrement or bat guano in closed areas (caves, mines, tunnels) or in open spaces (parks, orchards, and abandoned homes, among ...H. capsulatum, and two have ...
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