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HIV-1 disease progression

Mode of delivery and postpartum HIV 1 disease progression and mortality in a Kenyan cohort

Mode of delivery and postpartum HIV 1 disease progression and mortality in a Kenyan cohort

... maternal HIV-1 disease progression, and included longitudinally collected immunologic and virologic markers of disease progression including CD4 + and HIV-1 RNA ...

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Dynamics of Naive and Memory CD4+ T Lymphocytes in HIV 1 Disease Progression

Dynamics of Naive and Memory CD4+ T Lymphocytes in HIV 1 Disease Progression

... is to build on our healthy model by including HIV-1 infection. We maintain varying circulation characteris- tics of memory and naive cells as in the baseline model and include their individual ...

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Role of viral evolutionary rate in HIV 1 disease progression in a linked cohort

Role of viral evolutionary rate in HIV 1 disease progression in a linked cohort

... HIV disease is a complex interplay of both host and viral factors [6-10], but it has been difficult to derive a consen- sus on these factor(s) that contribute to disease progres- sion and / or ...of ...

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Role of common human TRIM5α variants in HIV 1 disease progression

Role of common human TRIM5α variants in HIV 1 disease progression

... Study participants (n = 979) were recruited within the genetics project of the Swiss HIV Cohort Study [18]. The ethics committees of all participant centers approved the study. Patients gave written informed ...

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Replication Capacity of Viruses from Acute Infection Drives HIV-1 Disease Progression

Replication Capacity of Viruses from Acute Infection Drives HIV-1 Disease Progression

... with disease progression, we did not expect the Gag-Pro-mediated RC to strongly correlate with the viral ...of disease progression (21, ...on disease progression ultimately ...

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Alterations in Cardiac and Pulmonary Function in Pediatric Rapid Human Immunodeficiency Virus Type 1 Disease Progressors

Alterations in Cardiac and Pulmonary Function in Pediatric Rapid Human Immunodeficiency Virus Type 1 Disease Progressors

... the HIV-1 disease progression categories is in group IIa pa- tients, and in the comparison between group IIa and IIb, all whom were followed prospectively from ...at 1 year of age was ...

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The Role of Regulatory T Cells during Feline Immunodeficiency Virus Pathogenesis

The Role of Regulatory T Cells during Feline Immunodeficiency Virus Pathogenesis

... of HIV-1 disease progression, including antiviral responses, immune activation, CD4 + T cell levels, and viral load have implicated Treg cells as regulators of the immune response to ...

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Heterozygosity for a defective gene for CC chemokine receptor 5 is not the sole determinant for the immunologic and virologic phenotype of HIV infected long term nonprogressors

Heterozygosity for a defective gene for CC chemokine receptor 5 is not the sole determinant for the immunologic and virologic phenotype of HIV infected long term nonprogressors

... of HIV-1 disease progression (43– ...of disease progression in infected ...to HIV infection and disease progression ...to HIV-1 coreceptors, it ...

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Gender Differences in Lymphocyte Populations, Plasma HIV RNA Levels, and Disease Progression in a Cohort of Children Born to Women Infected With HIV

Gender Differences in Lymphocyte Populations, Plasma HIV RNA Levels, and Disease Progression in a Cohort of Children Born to Women Infected With HIV

... of HIV-infected pregnant women re- cruited into the WITS between 1989 and September ...with HIV DNA polymerase chain reaction assays and/or HIV ...as HIV infected through consultation with a ...

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Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection

Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection

... of HIV-1 Gag-protease RC in subtype B infection have indicated that fitness- costly immune escape mutations selected in early infection are largely compensated for via secondary mutations by chronic ...

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Treatment and disease progression in a birth cohort of vertically HIV-1 infected children in Ukraine

Treatment and disease progression in a birth cohort of vertically HIV-1 infected children in Ukraine

... of HIV-infected children with established status in Ukraine were under institutional care by the end of July 2007 ...the HIV epidemic, usually associated with maternal IDU and marginalised social status of ...

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Intrahost human immunodeficiency virus type 1 evolution is related to length of the immunocompetent period.

Intrahost human immunodeficiency virus type 1 evolution is related to length of the immunocompetent period.

... type 1 (HIV-1) isolates are observed within in- fected individuals (12, 20, 23, 34, 35, ...the HIV-1 external glycoprotein gp120 has been shown to directly influence the ...

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SHIV 1157i and passaged progeny viruses encoding R5 HIV 1 clade C env cause AIDS in rhesus monkeys

SHIV 1157i and passaged progeny viruses encoding R5 HIV 1 clade C env cause AIDS in rhesus monkeys

... of HIV infections should not only reflect key aspects of HIV transmission among humans, but also mirror the tar- get cell specificity during acute infection and the natural, gradual disease ...

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Meta-Analysis To Test the Association of HIV-1 nef Amino Acid Differences and Deletions with Disease Progression

Meta-Analysis To Test the Association of HIV-1 nef Amino Acid Differences and Deletions with Disease Progression

... in HIV-1 infection ...halting disease progression in infected drug abusers in Italy (11), and premature stop codons were observed at equivalent, yet low, frequencies among the different ...

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Fluidity of HIV-1-Specific T-Cell Responses during Acute and Early Subtype C HIV-1 Infection and Associations with Early Disease Progression

Fluidity of HIV-1-Specific T-Cell Responses during Acute and Early Subtype C HIV-1 Infection and Associations with Early Disease Progression

... chronic HIV-1 infection has been asso- ciated with lower viral loads (15, 25, 34, 48, 55), whereas Env- and Nef-specific CD8 ⫹ T-cell responses have been associated with higher viremia (15, 34, ...

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The relationships between the HIV test interval, demographic factors and HIV disease progression

The relationships between the HIV test interval, demographic factors and HIV disease progression

... than a month beforehand. Thus, a short test interval is likely to be an imperfect proxy for seroconversion illness, although it may be sufficient for most purposes. The majority of the individuals included in the study ...

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HIV 1 subtype C envelope characteristics associated with divergent rates of chronic disease progression

HIV 1 subtype C envelope characteristics associated with divergent rates of chronic disease progression

... In HIV-1 subtype B, the relationship between HIV-1 Env diversity and disease progression is complex, as illu- strated by a series of ...study, HIV-1 Env ...

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Genetic Determinants of Pediatric HIV-1 Infection: Vertical Transmission and Disease Progression Among Children

Genetic Determinants of Pediatric HIV-1 Infection: Vertical Transmission and Disease Progression Among Children

... maternal HIV-infected cells is likely to be very ...nal HIV-infected cells or free virus-bearing maternal major histocompatibility complex (MHC) determi- nants can account for protection of some children ...

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Changes in Human Immunodeficiency Virus Type 1 Fitness and Genetic Diversity during Disease Progression

Changes in Human Immunodeficiency Virus Type 1 Fitness and Genetic Diversity during Disease Progression

... the HIV-1 ...ing disease progression and in the absence of drug pressure, selective pressure is likely due to both innate and acquired immune ...cell-mediated HIV-spe- cific immune ...

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Pediatric Viral Human Immunodeficiency Virus Type 1 RNA Levels, Timing of Infection, and Disease Progression in African HIV-1-Infected Children

Pediatric Viral Human Immunodeficiency Virus Type 1 RNA Levels, Timing of Infection, and Disease Progression in African HIV-1-Infected Children

... in HIV-1 RNA levels should be taken into account when using VL measures in young children to evaluate ARV drug ...Primary HIV-1 infection in children may also be influenced by the timing of ...

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