HIV-1 replication
Broad Recognition of Circulating HIV-1 by HIV-1-Specific Cytotoxic T-Lymphocytes with Strong Ability to Suppress HIV-1 Replication
... ABSTRACT HIV-1-specific cytotoxic T-lymphocytes (CTLs) with strong abilities to suppress HIV-1 replication and recognize most circulating HIV-1 strains are candi- dates for ...
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Suppression of HIV 1 replication by microRNA effectors
... Induced Silencing Complex (RISC) where miRNA* is degraded while miRNA serves as a guide for mRNA target- ing [2]. Key components of miRISC are proteins of the Argonaute family (Ago1 to Ago4) that are required for ...
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Restriction of HIV-1 replication by unique TRIM22 isoforms.
... restrict HIV-1 replication in vitro [131, 134, 144, 145], the degree to which these isoforms restrict HIV-1 in comparison to each other is ...performed HIV-1 release ...a ...
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Host hindrance to HIV 1 replication in monocytes and macrophages
... of HIV-1 replication in monocytes The early events of viral entry are represented by the engagement between CD4 receptors at the membrane of target cells and the viral envelope proteins ...
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The Long Noncoding RNA HEAL Regulates HIV 1 Replication through Epigenetic Regulation of the HIV 1 Promoter
... suppresses HIV-1 replication, we asked if the inverse is true: can HEAL overexpression enhance HIV-1 replication? We first mapped the full-length sequence of HEAL by performing 5= ...
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The dual role of tetraspanin CD63 in HIV 1 replication
... stage HIV-1 replication, CD63 siRNA was transfected into U1/HIV-1 cells, which are chronically infected monocytoid cells harboring 2 integrated copies of provirus per cell ...of ...
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DBR1 siRNA inhibition of HIV 1 replication
... of HIV-1 replication with RNAi has already been demon- strated with siRNAs against a variety of structural or regu- latory genes including gag, pol, nef, vif, tat, env and rev [16- ...an ...
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Strong In Vivo Inhibition of HIV 1 Replication by Nullbasic, a Tat Mutant
... the HIV-1 transcriptional activator protein (Tat) that strongly inhibits HIV-1 transcription and replication in lymphocytes in ...(postinfection) HIV-1 ...inhibited ...
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Molecular strategies to inhibit HIV 1 replication
... inhibit HIV-1 fusion and entry ...inhibits HIV-1 fusion and entry, but only moderately inhibits SU binding ...inhibits HIV-1 fusion ...inhibit HIV-1 ...
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Abrogation of in vitro suppression of human immunodeficiency virus type 1 (HIV-1) replication mediated by CD8+ T lymphocytes of asymptomatic HIV-1 carriers by staphylococcal enterotoxin B and phorbol esters through induction of tumor necrosis factor alpha.
... CD8 1 T lymphocytes of asymptomatic human immunodeficiency virus type 1 (HIV-1) carriers (AC) suppress HIV-1 replication in ...viral replication in peripheral blood ...
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Inhibition of HIV 1 replication by P TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P TEFb from the large, inactive form of the complex
... against HIV at non-cytotoxic concentrations is not ...impact HIV-1 replication and maintaining such levels would be associated with unacceptable levels of ...viral replication ...
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Analysis of CA Content and CPSF6 Dependence of Early HIV 1 Replication Complexes in SupT1 R5 Cells
... wild-type HIV-1 and a CPSF6 binding-defective variant carrying the A77V mutation in CA revealed no obvious difference until subviral complexes reached the nuclear ...subviral HIV-1 complexes ...
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Dual role of autophagy in HIV-1 replication and pathogenesis
... enabling HIV-1 to subvert autophagy in macrophages have been elucidated ...that HIV-1 Gag and Nef interact with the autophagy proteins LC3 and Beclin 1 ...of HIV-1 ...
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L-2-oxothiazolidine-4-carboxylic acid inhibits human immunodeficiency virus type 1 replication in mononuclear phagocytes and lymphocytes.
... of HIV-1 infection to AIDS (18, 35, ...of HIV infection and AIDS (5, 8, 39, 40). Thus, treatment of HIV-1 infection with agents which restore systemic and intracellular GSH may be a ...
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Su2019_Article_PathogenicRoleOfTypeIInterfero.pdf
... to HIV-1 Disease and Persistence In Vivo With depletion of pDCs during persistent HIV-1 infection in humanized mice, HIV-1 replication was also elevated in blood and ...
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Human Immunodeficiency Virus Type 1 IIIB Selected for Replication In Vivo Exhibits Increased Envelope Glycoproteins in Virions without Alteration in Coreceptor Usage: Separation of In Vivo Replication from Macrophage Tropism
... ons, HIV-1 viral supernatants of HXB2 or HXB2/LW were analyzed by RT (total virions) and infectious unit (infectious virions) ...entry. HIV-1 viral supernatants were used to infect the CXCR4- ...
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Interactions between human immunodeficiency virus type 1 and human cytomegalovirus in human term syncytiotrophoblast cells coinfected with both viruses.
... type 1 (HIV-1) may interact in the pathogenesis of ...of replication of HIV-1 and HCMV in singly an dually infected human term syncytiotrophoblast cells cultured in ...for ...
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Lentiviral Vectors Encoding Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Receptor Genes Efficiently Convert Peripheral Blood CD8 T Lymphocytes into Cytotoxic T Lymphocytes with Potent In Vitro and In Vivo HIV-1-Specific Inhibitory Activity
... into HIV-1-specific CTLs that potently suppress in vivo HIV rep- ...the HIV-1 Gag epitope, SL9 (amino acids 77 to 85; SLYNTVATL), play an important role in controlling viral ...
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Expression profile of host restriction factors in HIV 1 elite controllers
... suppress HIV-1 replication, while target cell activa- tion promotes HIV-1 transactivation, replication, and production [24,25]; therefore, consideration of these two parameters ...
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Functional Analysis of the Human Immunodeficiency Virus Type 1 Rev Protein Oligomerization Interface
... of HIV-1 encodes a key activity for the complex regulation of viral gene ...the HIV-1 replication cycle to bring about the export from the nucleus to the cytoplasm of incompletely ...
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