HIV-infected T-cell
Immunotherapy with an HIV-DNA Vaccine in Children and Adults
... Therapeutic HIV immunization is intended to induce new HIV-specific cellular immune responses and to reduce viral load, possibly permitting extended periods without antiretroviral ...C HIV-DNA ...
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Efficient Nef-Mediated Downmodulation of TCR-CD3 and CD28 Is Associated with High CD4+ T Cell Counts in Viremic HIV-2 Infection
... Jurkat T cells transfected with Nef expression constructs and in primary T cells infected with viral constructs expressing these nef alleles in the present study (data not ...Several HIV-2 ...
15
A role for CD81 on the late steps of HIV 1 replication in a chronically infected T cell line
... in HIV-1 [54], either CD81/ CD82 or CD63 are incorporated into virion particles sim- ply because of their presence at the assembly site ...for HIV-1 production in MOLT/HIV-1 cells ...for HIV-1 ...
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Total HIV DNA: a global marker of HIV persistence
... of infected cells are in tissues and that the blood contains only a small number of infected ...+ T lymphocytes and HIV RNA in plasma, whereas they are routinely used and they represent ...
7
Gut and mesenteric lymph node involvement in pediatric patients infected with human immunodeficiency virus
... showed HIV- RNA levels significantly higher than those in patients without mesenteric lymph nodes (P = ...+ T-cell percentage (P = ...+ T-cell absolute count (P = ...an HIV viral ...
6
Impaired CD4 T Cell Memory Response to Streptococcus pneumoniae Precedes CD4 T Cell Depletion in HIV-Infected Malawian Adults
... those infected with HIV ($500 (n = 627), 350–500 (n = 729), #350 (n = 15216) CD4 T cells/ml ...CD4+ T cell proliferative responses in media only, ...the cell population that ...
10
Enhanced T cell recovery in HIV 1–infected adults through IL 7 treatment
... + T cell deficiency, but efficient combination antiretroviral therapy (c-ART) restores T cells and decreases morbidity and ...prolonged T cell deficiency remains in a substantial ...
12
Glycoproteomic analysis identifies human glycoproteins secreted from HIV latently infected T cells and reveals their presence in HIV+ plasma
... from T cells infected with human immunodeficiency virus (HIV) latent infection may provide insight into understanding the host response to HIV infection in ...to HIV. In order to ...
11
Quantitative and Qualitative Differences in the T Cell Response to HIV in Uninfected Ugandans Exposed or Unexposed to HIV-Infected Partners
... their T cell responses to HIV peptides with those of unexposed uninfected ...the HIV-specific response in exposed versus unexposed uninfected ...to HIV was detectable in unex- posed ...
11
Bronchoalveolar CD4+ T cell responses to respiratory antigens are impaired in HIV-infected adults
... particular, HIV-infected individuals are 30 times more likely than uninfected adults to suffer from bacterial pneumonia or active ...of HIV infection, with over nine countries, including Malawi, ...
10
Selected Drugs with Reported Secondary Cell-Differentiating Capacity Prime Latent HIV-1 Infection for Reactivation
... hybrid-polar cell- differentiating anticancer agent, a further development/enhance- ment of HMBA ...its cell-differ- entiating effect at 100-fold-lower concentrations than those of HMBA ...some ...
15
HLA-B*44 Is Associated with a Lower Viral Set Point and Slow CD4 Decline in a Cohort of Chinese Homosexual Men Acutely Infected with HIV-1
... higher T cell responses to p24 for the A*02, A*24, B*27, and B*58 supertypes but not for the B*44 supertype in HIV-1 C subtype patients ...higher HIV-spe- cific T cell responses ...
7
Epigenetic control of HIV-1 post integration latency: implications for therapy
... reverse HIV-1 latency in infected patients but with limited ...the HIV-1 expression in latently in- fected T-cell lines, monocytic cell lines, and patients- derived primary cells ...
12
Role of Human Immunodeficiency Virus (HIV)-Specific T-Cell Immunity in Control of Dual HIV-1 and HIV-2 Infection
... (33). HIV-1-infected subjects with the ability to respond to HIV-2 Gag, as well as HIV-1 protein products had lower HIV-1 plasma viral loads than those without “cross- reactive” ...
11
Higher Homologous and Lower Cross-Reactive Gag-Specific T-Cell Responses in Human Immunodeficiency Virus Type 2 (HIV-2) Than in HIV-1 Infection
... effective HIV-specific T-cell responses in HIV-2-infected patients than in HIV-1- infected patients has been hypothesized, but the findings thus far have been ...
10
Timing of the Components of the HIV Life Cycle in Productively Infected CD4+ T Cells in a Population of HIV-Infected Individuals
... of HIV-infected individuals, as assessed here. After exposure to HIV, p24 appears in the cytoplasm of the infected cell after 1 h ...with HIV DNA peaking during single-round ...
8
A Novel Single Cell FISH Flow Assay Identifies Effector Memory CD4+ T cells as a Major Niche for HIV 1 Transcription in HIV Infected Patients
... treated HIV-infected patients, romidepsin significantly increased the percentage of cells expressing HIV RNA; however, we were not able to detect a significant production of viral ...upon cell ...
18
Mode of Transmission Affects the Sensitivity of Human Immunodeficiency Virus Type 1 to Restriction by Rhesus TRIM5α
... CD4 T cells cannot establish a sus- tained infection in cocultured rhesus CD4 T ...of HIV pathogenesis ...to HIV-1 infection, SIV or SHIV strains have been employed almost exclusively in these ...
12
Immunological abnormalities in human immunodeficiency virus (HIV) infected asymptomatic homosexual men HIV affects the immune system before CD4+ T helper cell depletion occurs
... persistent HIV infection on the immune system, we studied leukocyte functions in 14 asymptomatic homosexual men (CDC group II/III) who were at least two years seropositive, but who still had normal numbers of ...
8
Cytocidal effect of tumor necrosis factor on cells chronically infected with human immunodeficiency virus (HIV): enhancement of HIV replication.
... The viability of human T-cell line MOLT-4/HIV, chronically infected with HIV, was affected by the addition of a low dose 10 ng/ml of recombinant TNF-a rTNF-t, while uninfected MOLT-4 cel[r] ...
6