HLA Class II
Gains and Losses of HLA Class II (DR) and CD4 in Atypical Hyperplasia, Carcinoma in situ and Infiltrating Ductal Carcinoma of the Breast
... of HLA class II (DR) by epithelial neoplastic cells was possibly mediated by stro- mal T helper lymphocytes as lymphoid cell infiltrates were observed to all biopsy specimens containing HLA ...
6
HLA Class II Profile and Distribution of HLA-DRB1 and HLA-DQB1 Alleles and Haplotypes among Lebanese and Bahraini Arabs
... In view of the heterogeneity of the Arab population, which comprises people of distinct ethnic backgrounds and whose origins can be classified according to their area of habitation (North Africa, Arabian peninsula, and ...
5
HLA class II DR and DQ genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient population of Latvian children
... The HLA DRB1, DQA1 and DQB1 allele frequencies in patients and control subjects were ...of HLA class II were determined by gene counting ...
9
Genetic Polymorphisms HLA Class II in SIRS and Sepsis in Children
... the HLA genes including HLA class II (DRB1/DQA1/DQB1); HLA-III class (heat shock protein (HSP); complement factor B; complement components 2, 4A, and 4B; TNF-a and TNF-b ...
12
Epstein-Barr virus uses HLA class II as a cofactor for infection of B lymphocytes.
... lack HLA class II can be superinfected only if HLA class II expression is ...Type II bare-lymphocyte syndrome (BLS) is a rare severe primary immunodeficiency that is ...
6
HLA Class II Polymorphisms and Susceptibility to Recurrent Respiratory Papillomatosis
... HLA class II ...specific HLA class II alleles (3, ...for HLA class II (HLA-DR, HLA- DRw, and HLA-DQ) using low-resolution SSP-PCR (Table ...
13
HLA Class Ii Allele and Haplotype Associations with Type 1 Diabetes in Jeddah, Saudi Arabia
... Abstract: Type 1 diabetes (T1D) is a chronic autoimmune disorder caused by the destruction of the β-cells of pancreas. Genetic and environmental factors are involved in the pathogenesis of T1D. This study aimed to ...
11
Pathogenetic relevance of HLA class II expressing thyroid follicular cells in nontoxic Goiter and in Graves' disease
... by HLA class II expressing thyroid follicular cells thus only occurs in Graves' disease, suggesting that HLA class II expression on thyroid follicular cells is an essential ...
8
HLA class II restricted minor histocompatibility antigens - identification, processing and biology
... these HLA class II antigens are immunogenic and efficiently presented by (specific subsets of) professional APC in ...of HLA class II antigens towards HLA- DM is ...
191
Comparison of Antiretroviral Therapy (ART) Efficiency and Different HLA Class II Haplotypes
... However, in view of the HLA polymorphism, it is necessary to determine the best association with the HLA class II haplotypes thus improving therapy efficiency. According to Infectology Centre ...
10
Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells
... of HLA class II processing after exposure of either the apical or basolateral surface to a protein antigen, and a schematic model is pre- sented in ...of class II expression on the ...
13
Efficient Incorporation of HLA Class II onto Human Immunodeficiency Virus Type 1 Requires Envelope Glycoprotein Packaging
... for HLA class II protein incorporation and whether the absence of the 43-aa sequence disrupts the con- formation of other regions of ...efficient HLA class II protein incorpora- ...
6
A humanized model of experimental autoimmune uveitis in HLA class II transgenic mice
... in HLA class II TG mice described here provides evidence in favor of an involvement of class II–restricted responses in human ...of HLA-DR3 TG mice to disease induced with ...of ...
11
Human HLA class I- and HLA class II-restricted cloned cytotoxic T lymphocytes identify a cluster of epitopes on the measles virus fusion protein.
... Among the HLA class I-restricted F-specific CTL clones that were generated from the PBMC of children with acute measles, clone 2-F40 recognized an F epitope presented by HLA-B27 molecule[r] ...
9
Prevalence, clinical relevance and characterization of circulating cytotoxic CD4+CD28 T cells in ankylosing spondylitis
... ence or absence of stimulation by cross-linking the T cell receptor with immobilized anti-CD3 (OKT3). The T2-B27 cell line expresses a variety of different forms of HLA-B27, including free B27 H chain monomers, ...
9
Specific HLA-DRB and -DQB Alleles and Haplotypes Confer Disease Susceptibility or Resistance in Bahraini Type 1 Diabetes Patients
... with HLA class II genes, with certain allelic combinations conferring disease susceptibility or resistance, this study assessed the distributions of HLA-DR and -DQ among 107 unrelated patients ...
5
Computational modeling and analysis of prominent T-cell epitopes for assisting in designing vaccine of ZIKA virus
... antigen class II alleles in humans (DRB1*07:01, DRB1*01:01, DRB1*04:01, DRB1*08:02, DRB1*03:01, DRB1*11:01, DRB1*15:01, DRB1*13:02) [19] and used ProPred ...of HLA class II on the basis ...
7
HLA and proteasome expression body map
... of HLA expression in these substructures revealed very similar median classical HLA class I and HLA class II expression levels within the same tissue (Additional file 2: Figure ...
12
Dendritic Cells and Macrophages Are Productively Infected by Poliovirus
... the HLA class II molecules is de- pendent upon cellular uptake of exogenous protein by phago- cytosis or ...onto HLA class II molecules stored within the CIIV compartment of ...
9
StreptInCor: a model of anti-Streptococcus pyogenes vaccine reviewed
... the HLA class II alleles coded by the HLA- DRB1 and DQB1 genes, and studies with diverse genetic backgrounds led to multiple HLA class II alleles being associated with the ...
5