HMEC-1
Original Article Effects of CASP5 gene overexpression on angiogenesis of HMEC-1 cells
... endothelial HMEC-1 cells by recombinant ...in HMEC-1 cells did not affect the expression level of angpt-1 and cell proliferation ability, while it did promote angpt-2 expression and ...
7
Induction of multiple drug resistance in HMEC-1 endothelial cells after long-term exposure to sunitinib
... Abstract: Multiple drug resistance is still an unsolved problem in cancer therapy. Our previous study demonstrated that the chemotherapeutic drug doxorubicin (Dox) induced upregulation of P-glycoprotein (P-gp) in ...
7
Characterization of immortalized human dermal microvascular endothelial cells (HMEC-1) for the study of HDL functionality
... of HMEC-1 to internalize HDL particles by labeling the protein moiety; our data clearly showed that HMEC-1 were able to internalize HDL ...
8
Role of chemerin, a novel adipochemokine, in the human microvascular endothelial cell (HMEC) 1 line
... HMEC-1 cells were treated with different chemerin (21-157) concentrations [0- 10nM] for 24 hours. Following cell lysis and sample preparations, the protein lysates were separated using 8% polyacrylamide ...
352
A fermented bean flour extract downregulates LOX-1, CHOP and ICAM-1 in HMEC-1 stimulated by ox-LDL
... lipoprotein; HMEC-1, human microvascular endothelial cells; HUVEC, human umbilical vein endothelial cells; IL-6, interleukin-6; ICAM-1, intracellular adhesion molecule; LOX-1, lectin-like ...
11
Human Skin Endothelial Cells Can Express All 10 TLR Genes and Respond to Respective Ligands
... The human skin is well protected against pathogen inva- sion by various mechanisms that represent the so-called first line of defense. However, this protection works only in the intact skin, and once the barrier function ...
9
Trapp, Anja (2006): Einfluss von Immunsuppressiva auf die Endothelfunktion und Interaktion von Dendritischen Zellen mit Endothelzellen.. Dissertation, LMU München: Medizinische Fakultät
... Wie schon oben beschrieben, ist der Zusammenhang zwischen oxidativem Stress und den vasoaktiven Mediatoren NO und ET-1 recht komplex. Unsere Ergebnisse der MMF Stimu- lation von Endothelzellen ergaben in ...
110
Endothelial fibrinolytic response onto an evolving matrix of fibrin
... the HMEC-1 on a fibrin layer (model 2), thin fibrin films of 30 μL were formed on the bottom of the 96-well microplate, using the same clotting condition as model ...with 1 mM RGD were seeded on the ...
9
Culture and detection of primary cilia in endothelial cell models
... the HMEC-1 cell type. We are able to report that HMEC-1s are ciliated in every treatment we ...general, HMEC-1s have a higher cilia incidence than HUVECs, and have increased cilia incidence in ...
12
Human Parvovirus B19 NS1 Protein Modulates Inflammatory Signaling by Activation of STAT3/PIAS3 in Human Endothelial Cells
... Control cell extracts and Western blot analysis. IFN-␥- and IL-6-stimulated cells (each 100 ng/ml for 30 min at 37°C; Cell Signaling, Beverly, MS) were used as positive controls for STAT1 and STAT3 phosphorylation, ...
11
Original Article FasL on human nucleus pulposus cells prevents angiogenesis in the disc by inducing Fas-mediated apoptosis of vascular endothelial cells
... in HMEC-1 cells ...of HMEC-1 cell apoptosis with the activation of downstream FADD and ...in HMEC-1 cells following co- cultured with NP cells, which might be closely linked with ...
10
Bayesian hierarchical stochastic inference on multiple, single cell, latent states from both longitudinal and stationary data
... The available data, acquired from Xue et al. (2015b) although most images are self processed to obtain the raw data, have been obtained from fluorescent images of a reporter of Nrf2 protein in human endothelial ...
256
Chemerin induces endothelial cell inflammation: activation of nuclear factor kappa beta and monocyte endothelial adhesion
... Figure 3: Chemerin increases endothelial cell adhesion molecules protein expression in HMEC-1 cells. Serum starved HMEC-1 cells were treated with chemerin (0-10nM) for 12 and 24 hours. ...
14
Induction of acquired drug resistance in endothelial cells and its involvement in anticancer therapy
... EGF, 1 μg/ml hydrocortisone, 100 units/ml penicillin, and 100 μg/ml streptomycin as described elsewhere ...Dox-resistant HMEC cells were obtained by continuously exposing cells to escalating concentrations ...
12
Competitive suppression of dengue virus replication occurs in chikungunya and dengue co infected Mexican infants
... both HMEC-1 and Vero cells to assess whether this could be due to DENV suppression by ...and HMEC-1 cells in- fected with CHIKV, DENV-1 and DENV-2 strains obtained from Mexican subjects ...
11
Electroporation of human microvascular endothelial cells: evidence for an anti-vascular mechanism of electrochemotherapy
... alone. HMEC-1 cells were moderately sensitive to continuous exposure to cisplatin, but showed greater sensitivity to ...of HMEC-1 cells with bleomycin for a 5 min exposure was ˜250-fold better ...
6
Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells
... Human microvascular endothelial cells (HMEC-1) are derived from dermal foreskin. Cells were cultured in MCDB131 (Sigma-Aldrich, Gillingham, UK) medium supplemented with 10% foetal bovine serum (FBS), 50U/ ...
8
Rath, Sebastian (2012): Anti-angiogenic effects of cytotoxic, microbial derived compounds - Evaluation of the tubulin inhibitor pretubulysin and its derivatives and characterization of the v-ATPase inhibitor concanamycin A. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... of HMEC-1 appears to be even increased, though treated with tenfold higher concentration ...comparison, HMEC-1 still possess membrane integrity ...
108
Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent based model supported by in vitro studies
... of HMEC: 1) agents could divide as long as there was open space surrounding them; 2) if there was no more open space, agents could still divide but would be compressed until they reached a minimum size; 3) ...
15
Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions
... and glioblastoma cells. Cx43 is specifically upregulated in the reactive astrocytes surrounding glioblastoma [8], suggesting that gap junctions at the tumor margins are involved in tumor cell invasion [4, 6, 8, 9] and ...
10