hnRNP K
Radiosensitization and downregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K) upon inhibition of mitogen/extracellular signal-regulated kinase (MEK) in malignant melanoma cells
... (hnRNP K) has been described to be essential for p53-mediated effects following DNA damage ...[5]. HnRNP K is an ubiquitously expressed ribonucleoprotein capable of shuttling between the ...
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EtpE Binding to DNase X Induces Ehrlichial Entry via CD147 and hnRNP K Recruitment, Followed by Mobilization of N WASP and Actin
... cytoplasmic hnRNP-K by a nanoscale intracellular antibody markedly attenuated bacterial entry and infection but not ...and hnRNP-K and activating N-WASP-dependent actin ...
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A crucial role for hnRNP K in axon development in Xenopus laevis
... of hnRNP K originally led us to anticipate that its knockdown would probably produce an early embryonic ...maternal hnRNP K through gastrula stages, possibly allowing embryos to bypass earlier ...
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Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a tissue biomarker for detection of early Hepatocellular carcinoma in patients with cirrhosis
... of hnRNP K as a tumor biomarker for detecting early HCC, especially the detection of early HCC from liver ...that hnRNP K is a specific biomarker for tumor tissue. Detecting hnRNP ...
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hnRNP K post transcriptionally co regulates multiple cytoskeletal genes needed for axonogenesis
... that hnRNP K affects axonogenesis through pleiotropic effects on targeted RNAs, we constructed a synthetic, non-coding RNA containing either one or three tandem repeats of the tripartite binding motif ...
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Bortezomib inhibits Burkitt’s lymphoma cell proliferation by downregulating sumoylated hnRNP K and c-Myc expression
... of hnRNP K, several other HMw bands were detected when the film was exposed for a longer time, which showed altered expression after bortezomib treatment (Supplementary ...of hnRNP K. These ...
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Magnetic Fractionation and Proteomic Dissection of Cellular Organelles Occupied by the Late Replication Complexes of Semliki Forest Virus
... PCBP1, hnRNP M, hnRNP C, and hnRNP K were in the vicinity of SFV RCs ...of hnRNP C and hnRNP M in HeLa cells increased SFV gene expres- sion and replication ...because ...
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A Proteomic Approach To Identify Candidate Substrates of Human Adenovirus E4orf6-E1B55K and Other Viral Cullin-Based E3 Ubiquitin Ligases
... Analysis and identification of putative E4orf6/E1B55K sub- strates. Figure 2A shows the master 2D gel generated from the study involving extracts of cells harvested at 24 and 48 h p.i., indicating species identified by ...
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hnRNP A1 interacts with the genomic and subgenomic RNA promoters of Sindbis virus and is required for the synthesis of G and SG RNA
... In addition to virus-encoded factors, many steps in virus infections involve host factors. Such virus-host interactions are crucial determinants of virus host range, replication, and pathology, offer insights into viral ...
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Heterogeneous Nuclear Ribonucleoprotein K Supports Vesicular Stomatitis Virus Replication by Regulating Cell Survival and Cellular Gene Expression
... hnRNP K alters the expression of TIA1, a known negative regulator of VSV ...Since hnRNP K is known to influ- ence expression of many cellular genes, we wondered whether its depletion alters ...
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The Drosophila hnRNP M homolog Rumpelstiltskin regulates nanos mRNA localization
... of hnRNP M (also known as HNRPM in mouse), which has been previously implicated as a splicing factor in both invertebrates and vertebrates (Gattoni et ...an hnRNP M homolog regulating the localization of an ...
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hnRNP I is required to generate the Ca2+ signal that causes egg activation in zebrafish
... Structurally, hnRNP I is composed of four RNA-recognition motifs (RRMs) with interdomain linker ...Zebrafish hnRNP I has the same domains as hnRNP I in other species, except that its amino-terminal ...
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Norovirus Genome Circularization and Efficient Replication Are Facilitated by Binding of PCBP2 and hnRNP A1
... and hnRNP A1 re- combinant proteins stabilized the 5=-3= interactions and formed ribonucleoprotein complexes with the 5= and 3= ends of the MNV-1 genomic ...or hnRNP A1 resulted in a reduction in virus ...
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Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis
... plant hnRNP protein, we investigated whether the glycine-rich hnRNP-like pro- tein AtGRP7 (Arabidopsis thaliana glycine-rich RBP 7) has an effect on miRNA ...first hnRNP-like protein in plants that ...
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Terrae Incognitae: Integrative Genomic Analysis of Hnrnp L Splicing Regulation
... proteins, hnRNP L can both enhance and repress alternative exon splicing, but the mechanisms by which these opposing regulatory functions may be effected by hnRNP L remain ...of hnRNP L-enhanced and ...
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Characterization of the hnRNP RALY in RNA transcription and metabolism
... During the first year of my PhD, I mainly participated to the ongoing characterization of the interaction of RALY with RNA. In fact, RALY was classified as an RBP, given the high similarity with hnRNP-C, but its ...
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Transposable elements modulate human RNA abundance and splicing via specific RNA protein interactions
... that hnRNP C preferentially binds antisense Alu elements in RNA, where it prevents U2AF65 binding and aberrant ...of hnRNP C alignments in antisense Alu elements throughout the ...
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Critical role of hnRNP A1 in HTLV 1 replication in human transformed T lymphocytes
... putative hnRNP A1 binding site has been identified, close to the minimal Rex binding site in the stem-loop D of the XRE (Fig ...for hnRNP A1, these results suggest that hnRNP A1 might be the effector ...
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Long noncoding RNA NEAT1 promotes cell proliferation and invasion by regulating hnRNP A2 expression in hepatocellular carcinoma cells
... the U2aF65 protein, which was compared with the igg control group. The fold enrichment of NEAT1 and hnRNP A2 in the anti-U2aF65 group is presented in the statistical graph. The data represent the average and ...
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Growth-arrest-specific 7C protein inhibits tumor metastasis via the N-WASP/FAK/F-actin and hnRNP U/β-TrCP/β-catenin pathways in lung cancer
... with hnRNP U, a pseudo-substrate of E3-ubiqutin ligase β-TrCP. The GAS7C/hnRNP U interaction results in the release of β-TrCP and this will facilitate the β-TrCP/β-catenin interaction, which increases the ...
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