Homeodomain Proteins
The transcriptional co factor Chip acts with LIM homeodomain proteins to set the boundary of the eye field in Drosophila
... terminal proline-rich domain (P-rich) (Ramain et al., 2000) and with Bicoid, Fushi tarazu and other homeodomain proteins through its other interaction domain (OID) (Torigoi et al., 2000) (Fig. 4A). To ...
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Sex-Specific Homeodomain Proteins Sxi1α and Sxi2a Coordinately Regulate Sexual Development in Cryptococcus neoformans
... 2 proteins from ...the proteins form a het- erodimeric complex that alters gene regulation: haploid-spe- cific genes are repressed, and this change allows diploid cells to undergo meiosis and ...the ...
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Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins
... Pbx1 proteins were no longer detected from day 6, but EGFP persisted up to 20 days post-electroporation (Fig. 3C and not shown). The proportion of electroporated cells ranged from 5 to 10% of blastema cells, ...
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Chip mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM HOM proteins Apterous and Lim1 regulate distal leg development
... HOM proteins in the specification of distinct segments of the leg, and the results are compatible with Ap-Chip-Bar, Bar- Chip and Lim1-Chip-Al forming transcriptional ...LIM-HOM proteins can interact ...
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Paired and LIM class homeodomain proteins coordinate differentiation of the C elegans ALA neuron
... elegans homeodomain transcription factors CEH-10, CEH-14 and CEH- 17 confer resistance to the sleep-inducing effect of EGF, which is mediated by the ALA ...
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Expression and Purification of Homeodomain
... HOX proteins differ through homeodomain proteins and seems to be related to their natures ...that homeodomain GST-HOX11 protein was extremely stable in induction of high cell densities; ...
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Mutational Analysis of the Drosophila homothorax Gene
... a homeodomain-con- ...MEIS proteins form TALE superfamily (Bu ¨ rglin ...conserved homeodomain, MEIS proteins share TALE class homeodomain proteins of the PBC family structural ...
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Transitions in Sexuality: Recapitulation of an Ancestral Tri- and Tetrapolar Mating System in Cryptococcus neoformans
... the homeodomain proteins and the other encoding the pheromone and pheromone receptors, first expanded to form two larger gene clusters via the acquisition of sex-related ...the homeodomain genes were ...
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Evolutionary origins of blastoporal expression and organizer activity of the vertebrate gastrula organizer gene lhx1 and its ancient metazoan paralog lhx3
... Lhx1 proteins from various organisms using an ‘activated’ form (Lhx1*) that has point- mutated LIM ...LIM homeodomain proteins must have occurred in the linker sequence (the LH linker) between the ...
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Overexpression Beadex Mutations and Loss-of-Function heldup-a Mutations in Drosophila Affect the 3′ Regulatory and Coding Components, Respectively, of the Dlmo Gene
... three homeodomain the fact that they often contain known transcriptional proteins in which these domains were recognized: lin- activation domains prompted the suggestion, and subse- 11, which functions in ...
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Segregation of telencephalic and eye field identities inside the zebrafish forebrain territory is controlled by Rx3
... The specification of the eye field is correlated with sustained expression of Pax6, Six3 and Rx1-Rx3, shown to be crucial for eye development (Bailey et al., 2004; Graw, 2003; Hanson, 2003; Mathers and Jamrich, 2000). Rx ...
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A phylogenetically conserved cis regulatory module in the Msx2 promoter is sufficient for BMP dependent transcription in murine and Drosophila embryos
... Protein titrations showed that oligonucleotides containing the TTAATT site and flanking sequence were capable of binding the homeodomain proteins Prx1b (Fig. 6D) and Msx2 (data not shown). A mutation in the ...
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Genome wide view of TGFβ/Foxh1 regulation of the early mesendoderm program
... paired homeodomain proteins Mixer and Bix2 were shown to physically interact with Smad2 to regulate gsc expression (Germain et ...these proteins play an important role in Nodal ...
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Specification of hypothalamic neurons by dual regulation of the homeodomain protein Orthopedia
... the homeodomain-containing gene, otpb, and the G-protein-coupled receptor, pac1 (also known as adcyap1r1 – ZFIN), that displayed a discernible expression pattern in the developing zebrafish hypothalamus (Figs 2, 3 ...
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Absence of Expression of OCT 2 in Gastric Cancer Cells
... OCT-2, a member of the POU homeodomain family of transcription factors, has been implicated in gastric cancer lymph node metastasis on a single publication so far. Other members of the same family of tran- ...
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Stem Cell Regulation by Arabidopsis WOX Genes
... the homeodomain appears interchangeable within the WUS clade, but also between WUS and ...on homeodomain DNA-specificity and that yet unknown tissue or developmental stage specific factors provide ...
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Vaccine delivery by penetratin: mechanism of antigen presentation by dendritic cells
... systems[13-28]. For this purpose peptides chemically conjugated to protein antigens or synthetic peptides of CPP fused in tandem with cytotoxic (Tc) or helper (Th) T cell epitopes have been used. Mice immunized with ...
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Smets, Martha (2017): Studies of UHRF1-mediated mechanisms regulating DNA methyltransferase 1. Dissertation, LMU München: Fakultät für Biologie
... Repressed genes are usually found in heterochromatic regions and are characterized by a combination of PTMs on histone tails, for example methylation of residues K27 and K9 of H3 and the ubiquitination of H2A on K119 ...
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AKT3 rSNPs, Transcriptional Factor Binding Sites and Human Disease
... The AKT3 SNPs (rs10157763, rs10927067 and rs- 2125230) are significantly associated with PCA [5]. The rs10157763 AKT3-C allele creates six unique TFBS for the ELF5, ELK1, Mycn, SPIB, SPI1 and TFAP2A TFs whose function ...
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Transcriptional Regulatory Logic of Valve Margin Patterning in Arabidopsis.
... As conservation of sequence correlates with function, we reasoned that these high scoring regions within the SHP2 5’ regulatory region may contribute to SHP2 regulation. The 9- scoring region located at -733bp lies ...
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