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Homologous Recombination

Impact of Homologous Recombination on the Evolution of Prokaryotic Core Genomes

Impact of Homologous Recombination on the Evolution of Prokaryotic Core Genomes

... specific recombination involving mobile genetic elements, whereas changes in the core genome generally involve vertical transmission and homologous recombination (HR) (3, ...

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Gene targeting and transgene stacking using intra genomic homologous recombination in plants

Gene targeting and transgene stacking using intra genomic homologous recombination in plants

... by homologous recombination (HR) or non-homolo- gous end joining ...sequences homologous (almost identical) to those flanking the DSB site [12, ...DNA recombination pathway dur- ing meiosis in ...

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Homologous recombination: from model organisms to human disease

Homologous recombination: from model organisms to human disease

... in homologous recombination (see Figure ...identical recombination partners and might thereby provide a mechanism to prevent recombina- tion between repetitive sequences that are dispersed through- ...

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Haploidization in Saccharomyces cerevisiae Induced by a Deficiency in Homologous Recombination

Haploidization in Saccharomyces cerevisiae Induced by a Deficiency in Homologous Recombination

... by homologous recombination (Krogh and Syming- ton 2004) and since nonhomologous recombination is sup- pressed in diploid cells (Shrivastav et ...

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Correlated Mutations and Homologous Recombination Within Bacterial Populations

Correlated Mutations and Homologous Recombination Within Bacterial Populations

... of homologous recombination within a bacterial population remains a key challenge in quantifying the basic parameters of bacterial ...detecting recombination events based on phylogenetic ...

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Impact of Homologous Recombination on Silent Chromatin in Saccharomyces cerevisiae

Impact of Homologous Recombination on Silent Chromatin in Saccharomyces cerevisiae

... ogous recombination with pseudo-MAT affected chromatin at the HML::cre locus in a way that did not manifest silencing loss immediately, resulting in a delay in cre transcription by one or two cell ...after ...

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Intramolecular homologous recombination in cells infected with temperature-sensitive mutants of vaccinia virus.

Intramolecular homologous recombination in cells infected with temperature-sensitive mutants of vaccinia virus.

... In order to delineate the viral gene products which participate in vaccinia virus recombination, I monitored intramolecular homologous recombination within a plasmid in cells infected wi[r] ...

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Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements

Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements

... by homologous recombination between two existing Alu repeats that flanked the ...26-bp recombination joint in the Alu sequence includes the 10-bp "B" sequence homologous to the RNA ...

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Methotrexate induces DNA damage and inhibits homologous recombination repair in choriocarcinoma cells

Methotrexate induces DNA damage and inhibits homologous recombination repair in choriocarcinoma cells

... Homologous recombination (HR) is a major repair pathway for DSB and proceeds accurately with sequential involvements of multiple ...another recombination mediator that possesses non-conserved ...

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Homologous Recombination-Directed Mechanisms of Alternative Lengthening of Telomeres

Homologous Recombination-Directed Mechanisms of Alternative Lengthening of Telomeres

... Homologous recombination (HR) is an evolutionarily conserved mechanism of DNA repair that is essential to genome integrity in meiotic and mitotic cells (Mazon et ...non- homologous end-joining (NHEJ) ...

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Genetic Requirements for Homologous Recombination in Autographa californica Nucleopolyhedrovirus

Genetic Requirements for Homologous Recombination in Autographa californica Nucleopolyhedrovirus

... on homologous recombination (HR) among bacu- lovirus genomes in cell culture and in the wild are limited, curtailing our understanding of genetic diversity among bacu- lovirus strains and virus evolution ...

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How homologous recombination generates a mutable genome

How homologous recombination generates a mutable genome

... Homologous recombination (HR) is one of the fundamental mechanisms of DNA processing which, in various guises, is found in all phyla of life. 1,2 HR is capable of playing several distinct roles within an ...

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Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers

Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers

... conservative homologous recombination repair of DNA double-strand ...a homologous recombination ...which homologous recombination deficiencies may arise beyond BRCA1/2 mutation ...

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The Saccharomyces cerevisiae Recombination Enhancer Biases Recombination During Interchromosomal Mating-Type Switching but Not in Interchromosomal Homologous Recombination

The Saccharomyces cerevisiae Recombination Enhancer Biases Recombination During Interchromosomal Mating-Type Switching but Not in Interchromosomal Homologous Recombination

... intramolecular homologous recombination (B), and interchromosomal ho- mologous recombination (C) is ...cases, recombination is initiated by formation of a recombinogenic lesion (*) at a ...

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BRCA2 and homologous recombination

BRCA2 and homologous recombination

... GFP recombination substrate to demonstrate that cells with defective BRCA2 protein are deficient in their ability to repair the I-SceI- induced DSB through homologous ...via homologous ...

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RadB acts in homologous recombination in the archaeon Haloferax volcanii, consistent with a role as recombination mediator

RadB acts in homologous recombination in the archaeon Haloferax volcanii, consistent with a role as recombination mediator

... Homologous recombination plays a central role in the repair of double-strand DNA breaks, the restart of stalled replication forks and the generation of genetic ...of recombination is essential since ...

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Resolving RAD51C function in late stages of homologous recombination

Resolving RAD51C function in late stages of homologous recombination

... DNA double strand breaks are efficiently repaired by homologous recombination. One of the last steps of this process is resolution of Holliday junctions that are formed at the sites of genetic exchange ...

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Ac induces homologous recombination at the maize P locus.

Ac induces homologous recombination at the maize P locus.

... However, in some M3 families (especially those derived from crosses with inbred B73) the identification of P-ww*/P-ww* plants was confounded by additional tassel pigmentation not[r] ...

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Homologous recombination involving a large heterology in Escherichia coli.

Homologous recombination involving a large heterology in Escherichia coli.

... We also detected the type expected from gene conversion at site b by appearance of a BglII site (data.. The plasmid preparations from the kanamycin-resist- ant clones from JC8[r] ...

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HOMOLOGOUS RECOMBINATION BETWEEN EPISOMAL PLASMIDS AND CHROMOSOMES IN YEAST

HOMOLOGOUS RECOMBINATION BETWEEN EPISOMAL PLASMIDS AND CHROMOSOMES IN YEAST

... Genetic recombination was observed at the same frequency with both types of plasmids, indicating that all such plasmids have ready access to (and most likely resi[r] ...

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