hot-melt extrusion
DISSOLUTION ENHANCEMENT OF POORLY WATER SOLUBLE EPROSARTAN BY HOT MELT EXTRUSION TECHNIQUE
... (hot melt extrusion) and comparison with other ...method, hot melt extrusion technique at ...by hot melt extrusion technique when compared to solvent ...
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Development and Characterisation of Natamycin Mini Matrices Prepared by Hot Melt Extrusion for Vaginal Delivery
... years, hot-melt extrusion technology has gained popularity due to pharmaceutical applications of poorly water-soluble ...In melt extrusion processes, the drug/carrier powder blend is ...
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SOLUBILITY AND DISSOLUTION ENHANCEMENT OF IVACAFTOR TABLETS BY USING SOLID DISPERSION TECHNIQUE OF HOT MELT EXTRUSION A DESIGN OF EXPERIMENTAL APPROACH
... of hot melt extrusion (HME) is one of the solid dispersion (SD) technique that efficient mixing of drug with polymer and inert excipient, progressive melting and finally ...polymer, extrusion ...
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FORMULATION AND IN VITRO EVALUATION OF GASTRORETENTIVE FLOATING DRUG DELIVERY OF VALSARTAN USING HOT MELT EXTRUSION TECHNIQUE
... utilizing hot melt extrusion technique (HME). Hot melt extrudates were prepared by novel polymeric matrices such as HPMCAS and Plasdone S630 copovidone at different ...its ...
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RECENT ADVANCES IN HOT MELT EXTRUSION TECHNOLOGY
... Melt extrusion process which is well known in the polymer and food industry is now being used for pharmaceutical manufacturing to create innovative new formulations and is a continuous process of mixing and ...
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A COMPARATIVE STUDY OF LEDIPASVIR SOLID DISPERSION TECHNIQUE USING SPRAY DRYING AND HOT MELT EXTRUSION
... Poorly water-soluble crystalline drugs, when in the amorphous state tend to have higher solubility. Drug in its amorphous state shows higher drug release because no energy is required to break up the crystal lattice ...
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ROLE OF MELT EXTRUSION IN THE ENHANCEMENT OF BIOAVAILABILITY
... dispersion. Hot Melt Extrusion (HME): Melt extrusion was used as a manufacturing tool in the pharmaceutical industry as early as ...that melt extrusion of miscible ...
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HOT MELT EXTRUSION AND FREEZE PELLETIZATION: BETTER ALTERNATIVE FOR DRUGS HAVING STABILITY PROBLEM DUE TO PRESENCE OF WATER
... in hot melt extrusion include release modifying agents which are added to improve the bulk, and processing agent which can impart specific properties to the dosage forms produced by hot ...
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DESIGN AND EVALUATION OF BILAYER TABLETS OF GLIMEPIRIDE AND METFORMIN HYDROCHLORIDE WITH COMBINATION OF HYDROPHILIC AND HYDROPHOBIC POLYMERS BY HOT MELT EXTRUSION
... The aim of the present study was to design and evaluate bilayered tablets of metformin hydrochloride as sustained release (SR) and glimepiride as immediate release form for the treatment of diabetes mellitus. Immediate ...
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SOLUBILITY AND DISSOLUTION RATE ENHANCEMENT OF ANTIFUNGAL VORICONAZOLE BY HOT MELT EXTRUSION AND DEVELOPMENT OF SUSTAINED RELEASE TABLETS
... Suppression of sharp endotherm in physical mixture indicates the favorable interaction between drug and polymer. Melt extrudate SD had no distinct melting endotherm for the Voriconazole which indicates the drug ...
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Aluminum Coating on Magnesium Based Alloy by Hot Extrusion and Its Characteristics
... the hot extrusion ...an extrusion die having an inversely angled face was successfully extruded together with the magnesium-based alloy billet and, as a result, the aluminum coated the extruded ...
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Study on Unqualified Mechanism of Extrusion Performance of Hot Rolled Q345D Plate
... In this paper, a systematic analysis of the failure performance of the slab after continuous hot rolling is carried out. The results show that the microstructure of Q345D steel plate is F + P, individual Class A ...
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Novel biopolymer constructs: physical properties and antimicrobial efficacy
... used melt extrusion to prepare PLA 14 based composites with cellulose and lignin particles and observed that the composite materials exhibited a biocidal activity against a tomato bacterial plant ...
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Wear Properties of Hot Extruded Aluminum Powder Compacts
... Improvement of densification and hence mechanical properties for powder metallurgical process can be achieved with size reduction which is widely, performed with hot extrusion process. Thus, the compacted ...
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Difficulties in the Use of Ground Bacterial Cellulose (BC) as Reinforcement of Polylactid Acid (PLA) Using Melt Mixing and Extrusion Technologies
... enced. SEM also showed a strong interfacial adhesion between BC and acrylic resin [14]. BC is mostly used in a so-called “never-dried” state and in some cases also as dissolution to produce a composite. In our research ...
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Research on Combined Hot Extrusion Forming Process of Alternator Poles
... or hot forging processes ...cal hot forging process includes two pre-forming opera- tions combined with forming, trimming and ...forward extrusion, setting, heading, piercing, trimming (on separate ...
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Tensile Properties and Blow Forming of 5083 Aluminum Alloy Recycled by Solid State Recycling
... images obtained by EPMA for the specimen from small machined chips and the virgin specimen, where the TD-ND plane is observed. In the specimen from small machined chips, the distinct peaks of oxygen were aligned to the ...
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Synthesis by extrusion : continuous, large scale preparation of MOFs using little or no solvent
... a melt phase. 11e Performing synthesis via melt phases remains unusual in coor- dination chemistry 13 and we are unaware of previous examples of continuous melt phase synthesis in this ...
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Equal Channel Angular Extrusion Technique for Controlling the Texture of n Type Bi2Te3 Based Thermoelectric Materials
... each extrusion temperature of ECAE in ...high extrusion temperature tend to be ...the extrusion temperature in ECAE processing is directly related to the average grain ...
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EFFECT OF EXTRUSION SPEED AND TEMPERATURE ON HOT EXTRUSION PROCESS OF 6061 ALUMINUM ALLOY CHIP
... Therefore, the temperature increase caused by friction factors between the workpiece and the tooling. Also the temperature, contour profile in the extrudate is very sharp, meaning that if taken a section at any point of ...
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