HPV-11
Variation of human papillomavirus type 6 (HPV 6) and HPV 11 genomes sampled throughout the world
... since HPV-6 and HPV-11 variants showed significant differences due to indels in the LCR, we decided to compare the most diverse variants for their enhancer ...the HPV-6a and HPV-6b ...
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The Carboxyl-Terminal Region of the Human Papillomavirus Type 16 E1 Protein Determines E2 Protein Specificity during DNA Replication
... the HPV-16 E1 protein (res- idues 1 to 365) does not play a role in E2 protein specificity, as 16/11 E1H1 and E1H2 exhibited high replication activities with both E2 proteins ...the HPV-16 protein ...
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Cellular Changes Induced by Low-Risk Human Papillomavirus Type 11 in Keratinocytes That Stably Maintain Viral Episomes
... of HPV-11-positive keratinocytes was al- tered in organotypic raft cultures, as was previously observed for cells transfected with high-risk HPV-31 or HPV-18 (3, 4, ...whether ...
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cis-Acting components of human papillomavirus (HPV) DNA replication: linker substitution analysis of the HPV type 11 origin.
... the HPV-11 E1 protein binds a DNA template with a mutated E1BS in order to initiate ...for HPV-11, as for BPV-1 (70, 86), tethering of E1 or the E1-E2 complex to the origin is necessary but ...
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Involvement of Nuclear Export in Human Papillomavirus Type 18 E6-Mediated Ubiquitination and Degradation of p53
... in HPV-positive cer- vical carcinoma cells, and p53 degradation is entirely depen- dent upon E6 function ...high-risk HPV-18 E6 but not low-risk HPV-11 E6 is able to accumulate predominantly ...
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Conditionally Activated E7 Proteins of High-Risk and Low-Risk Human Papillomaviruses Induce S Phase in Postmitotic, Differentiated Human Keratinocytes
... by HPV-11 E7ER is accompanied by nuclear import of ...with HPV-11 E7ER, S-phase reentry by cells in the differentiated strata was associated with E2-induced nuclear import of E7ER ...with ...
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Human papillomavirus type 1 produces redundant as well as polycistronic mRNAs in plantar warts.
... Oncogenic Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest HPV-11 and HPV-6 in splice site usage, major promoter locations, and the synthesis of two E1i^E4 mRNAs, one of[r] ...
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Role of the ATP-Binding Domain of the Human Papillomavirus Type 11 E1 Helicase in E2-Dependent Binding to the Origin
... the HPV origin in ...of HPV-11 E1 is sufficient for interaction with ...iments, HPV-11 E1 protein, which was tagged at its N terminus with a FLAG epitope, and HPV-11 E2 ...
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Progression and regression of incident cervical HPV 6, 11, 16 and 18 infections in young women
... Incident HPV 6, 11, 16 and 18 infections were identified on cervical swab or biopsy specimens among woman neg- ative for the relevant HPV type on their first 2 study swabs and any cervical biopsy ...
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The Hinge of the Human Papillomavirus Type 11 E2 Protein Contains Major Determinants for Nuclear Localization and Nuclear Matrix Association
... Immunofluorescence detection of E1 and E2 proteins. Indirect immunofluo- rescence to detect the HPV-11 E1 protein was conducted as described previously (61), with slight modifications (14). Briefly, the ...
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Mitogen-Activated Protein Kinases Activate the Nuclear Localization Sequence of Human Papillomavirus Type 11 E1 DNA Helicase To Promote Efficient Nuclear Import
... of HPV-11 E1 NLS by ...the HPV-11 E1 ATPase/DNA helicase is a substrate of MAPKs and that phosphorylation of both S89 and S93, in addition to the NLS, is crucial for efficient E1 nuclear ...in ...
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In vitro biological activities of the E6 and E7 genes vary among human papillomaviruses of different oncogenic potential.
... Our data obtained with the keratinocyte immortalization assay also show that E6 from the low-risk HPV types is less active than E6 from the high-risk types, since E6 from HPV-6 or HPV-11[r] ...
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Human papillomavirus type 11 and 16 E5 represses p21(WafI/SdiI/CipI) gene expression in fibroblasts and keratinocytes.
... of HPV-11 E5, driven by basal metallothionein promoter activity, somewhat suppressed p21 promoter activity in NE5a1 and KE5a cells, zinc induction of E5 gene expression led to further suppression of p21 ...
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Nuclear Matrix Attachment Regions of Human Papillomavirus Type 16 Point toward Conservation of These Genomic Elements in All Genital Papillomaviruses
... of HPV genomes in the nuclei of infected ...of HPV DNAs with the nuclear matrix. The endogenous genomes of HPV type 16 (HPV-16) which are present in SiHa, HPKI, and HPKII cells, adhere in vivo ...
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More men than women make mucosal IgA antibodies to Human papillomavirus type 16 (HPV 16) and HPV 18: a study of oral HPV and oral HPV antibodies in a normal healthy population
... elucidated. HPV infection has been shown to play an important role in all anogenital cancers with HPV seropositivity in men and women vary- ing according to the site of HPV infection ...of HPV ...
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p53 Protein Is a Suppressor of Papillomavirus DNA Amplificational Replication
... ment of apoptosis and distribution of cells in the cell cycle. In addition, the efficient rescue of CHO4.15 cells from the wt p53-induced apoptosis by Bcl2 expression did not affect the suppression of BPV-1 origin ...
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Characterization of human papillomavirus type 11 E1 and E2 proteins expressed in insect cells.
... To confirm that the HPV-11 proteins expressed in insect cells are biologically active, we assayed protein from crude nuclear extracts for a number of the activities which the HPV-11 prot[r] ...
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Regulation of human papillomavirus type 11 enhancer and E6 promoter by activating and repressing proteins from the E2 open reading frame: functional and biochemical studies.
... In this paper, we report the expression of HPV-11 E2-C, a protein consisting mainly of the carboxy-terminal 45% of the E2 protein, and the regulation of HPV-11 enhancer-SV40 early promot[r] ...
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Enhanced transcriptional activation by E2 proteins from the oncogenic human papillomaviruses.
... the HPV-16 and HPV-18 E2 proteins (solid lines) were much more active than were the HPV-6b and HPV-11 E2 proteins (dashed lines), and expression of the BPV-1 E2 pro- tein (dotted line) ...
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Accumulation of invariant NKT cells with increased IFN-γ production in persistent high-risk HPV-infected high-grade cervical intraepithelial neoplasia
... Five hundred microliters of denaturation reagent was added to the specimen transport medium, and the sam- ple was placed in a 65°C water bath for 45 minutes. Then, 75 μl of the mixture and 25 μl of the high-risk ...
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