HSV-1/HSV-2 Antibody
Peptide sequences of glycoprotein G-2 discriminate between herpes simplex virus type 2 (HSV-2) and HSV-1 antibodies.
... of HSV-2, encoded by the US4 gene, is a protein that is larger than the equivalent gG-1 protein of HSV-1 ...of HSV-2-specific ...which HSV-2 ...
5
Antibodies against six human herpesviruses in relation to seven cancers in black South Africans: A case control study
... log antibody measures for response to all six ...log antibody measures for response to all six of the ...HHV-6 antibody lev- els and the risk of oral cancer could have been caused by opportunistic ...
9
Regional Distribution of Antibodies to Herpes Simplex Virus Type 1 (HSV 1) and HSV 2 in Men and Women in Ontario, Canada
... type 2 (HSV-2) is a sexually transmit- ted virus that is the most common cause of genital ulceration ...of HSV-2 anti- bodies varies considerably by ...population, HSV-2 ...
6
Discrimination of Antibody to Herpes B Virus from Antibody to Herpes Simplex Virus Types 1 and 2 in Human and Macaque Sera
... have antibody to herpes B virus were found to show cross-reactivity with HSV-1, whereas only 5 showed cross-reactivity with ...all HSV-1- and HSV-2-seropositive macaques, ...
6
Differences in the Regulatory and Functional Effects of the Us3 Protein Kinase Activities of Herpes Simplex Virus 1 and 2
... that HSV-1 Us3 catalytic activity is required for induction of posttranslational modification of HDAC2 and for that of wild-type HSV-1 CPEs at 24 h postin- fection ...of HSV-2 ...
11
Herpes simplex virus infections among rural residents in eastern China
... HSV Antibody Testing: HSV type-specific IgG antibody was tested using an enzyme-linked immunosorbent assay (ELISA) technique (HerpeSelect 1 ELISA IgG Kit and HerpeSelect 2 ELISA ...
6
Tyrosine phosphorylation of the herpes simplex virus type 1 regulatory protein ICP22 and a cellular protein which shares antigenic determinants with ICP22.
... polyclonal antibody against full- length ICP22. The antibody described above, R10, was raised against a synthetic peptide consisting of only 17 ICP22 amino acids ...an antibody raised against the ...
5
Immunodominant “Asymptomatic” Herpes Simplex Virus 1 and 2 Protein Antigens Identified by Probing Whole-ORFome Microarrays with Serum Antibodies from Seropositive Asymptomatic versus Symptomatic Individuals
... known HSV-1 and/or HSV-2 infection based on physician examination or self-report but who never had symptoms typical of any herpes ...FIG 2 Intensities of antibody responses from ...
12
A Lentiviral Vector-Based, Herpes Simplex Virus 1 (HSV-1) Glycoprotein B Vaccine Affords Cross-Protection against HSV-1 and HSV-2 Genital Infections
... NaCl, 1% Triton, 1 mM EDTA, ...polyclonal antibody (9) diluted 1:4,000 in 1% skim milk and horseradish peroxidase FIG 1 Genomic maps of vector, packaging, and Env plasmids used ...
12
Impact of Valency of a Glycoprotein B-Specific Monoclonal Antibody on Neutralization of Herpes Simplex Virus
... of HSV gD to one of its cellular receptors, gB plays a role in virion attachment to target ...for HSV gB has been described (5, 24, 62). Paired immunoglobulin-like type 2 receptor (PILR ␣ ) has been ...
11
Cervicovaginal Neutralizing Antibodies to Herpes Simplex Virus (HSV) in Women Seropositive for HSV Types 1 and 2
... CVS HSV-specific ...to HSV-1- or HSV-2-infected cell-protein mixtures by enhanced chemiluminescence Western blotting (ECL-WB) as de- scribed in detail in reference ...with ...
6
Efficacy of the Herpes Simplex Virus 2 (HSV-2) Glycoprotein D/AS04 Vaccine against Genital HSV-2 and HSV-1 Infection and Disease in the Cotton Rat Sigmodon hispidus Model
... reduced HSV-1 replication to undetectable levels ...against HSV-1 genital herpes was achieved by the highest and intermediate gD/AS04 doses, which also caused significant reduction in vaginal ...
16
Protection Provided by a Herpes Simplex Virus 2 (HSV-2) Glycoprotein C and D Subunit Antigen Vaccine against Genital HSV-2 Infection in HSV-1-Seropositive Guinea Pigs
... virus 1 (HSV-1)-seropositive guinea pigs immunized and subsequently challenged intravaginally with ...study 1, HSV-2 glycoproteins C (gC2) and D (gD2) were produced in ...
11
Locations of herpes simplex virus type 2 glycoprotein B epitopes recognized by human serum immunoglobulin G antibodies.
... from HSV-1 2 /2 1 subjects reacted strongly with the amino-proximal gB-2 segment (aa 18 to 228) and with the carboxy-proximal segment (aa 228 to 903); 8 of 18 HSV-12/21 ...
7
The gH-gL Complex of Herpes Simplex Virus (HSV) Stimulates Neutralizing Antibody and Protects Mice against HSV Type 1 Challenge
... from HSV-1 challenge, we are somewhat at a loss to explain the failure of other laboratories to achieve a similar result in assays using gH-gL expressed as a complex in a re- combinant vaccinia virus ...
8
HSV-2 ΔgD elicits FcγR-effector antibodies that protect against clinical isolates
... all HSV-specific IgG in the skin), reached high titers (1:24,000) in skin biopsies by day 2 after challenge, and had low-level neutralizing activity (19) but mediated several Fc effector functions, ...
16
HSV 2 and HIV 1 permissive cell lines co infected by HSV 2 and HIV 1 co replicate HSV 2 and HIV 1 without production of HSV 2/HIV 1 pseudotype particles
... temperature. Antibody-bound viruses were then captured by magnetic separation according to the manufacturer's ...containing 2% fetal bovine serum ...biotinylated antibody to virus before capture ...
10
Herpes simplex virus 2 (HSV 2) type specific antibody correlates of protection in infants exposed to HSV 2 at birth
... in 1 of 4 infants of women with primary infection, in 3 of 9 infants of women with nonprimary first episode infection, and in none of the 27 infants of women with recurrent ...to HSV-2 proteins ...
5
Human antibody response to herpes simplex virus specific polypeptides after primary and recurrent infection
... Human antibody responses to specific polypeptides of herpes simplex virus types 1 and 2 HSV-1 and HSV-2, respectively were assessed in serial serum specimens from 18 infected patients by[r] ...
6
Mutational analysis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): characterization of HSV type 1 (HSV-1)/HSV-2 chimeras.
... a 2-h interval by using a Molecular Devices Thermo Max Microplate ...from HSV-1(KOS), and the thick lines represent viral sequences comprising the UL41 59 and 39 untranslated regions ...the ...
10