Human Adipose Tissue
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
... Global deletion of ACC1 in rodents results in embryonic lethality [26], but targeted liver-specific deletion, decreases lipogenesis and lipid accumulation without alteration in b- oxidation or glucose homeostasis [27]. ...
10
Phenylalanine kinetics in human adipose tissue
... of human adipose tissue is well documented with differ- ences in blood flow, lipolytic activity, and response to hor- monal stimuli among the various adipose tissue depots ...
7
The role of endoplasmic reticulum in human adipose tissue
... within human adipose tissue highlighted that weight gain, as noted through a cross-sectional study examining adipose tissue from lean and obese individuals, increased ER ...vivo ...
257
Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue
... on adipose tissue ceramides, which are more limited and almost entirely restricted to rodent models, link increased ceramides or ceramide derivatives in this tissue to obesity, insulin resistance and ...
12
Isolation and culture of microvascular endothelium from human adipose tissue
... from human foreskin, spleen, and ...50% human serum for growth and ...requirements, human adipose tissue was digested with collagenase and endothelial cells were separated from other ...
9
Mechanisms underlying regional differences in lipolysis in human adipose tissue
... It was also observed in this study that females exhibit a lower antilipolytic sensitivity to clonidine in the abdominal adipocytes as than in the gluteal adipocytes; no such difference w[r] ...
11
Clinical analysis of selected complement derived molecules in human adipose tissue
... In addition, our results showed depot-specific differences in AT-derived FIF levels of the examined complement anaphylatoxins/molecules. We found that approximately 2-fold higher levels of complement C3a and adipsin are ...
6
Lipogenesis in Human Adipose Tissue: Some Effects of Nibbling and Gorging
... Our finding that a high caloric intake was associated with incorporation of carbon from glucose and pyruvate in fatty acids 8 made it possible to examine the effects of varying the durat[r] ...
13
The Mechanism of Activation of Hormone Sensitive Lipase in Human Adipose Tissue
... Lipase activities against diolein and monoolein were not affected. Addition of protein kinase inhibitor at zero time completely inhibited activation, and this inhibition was prevented by prior addition of an excess of ...
9
Evaluation of the reference genes in human adipose tissue and lipoma samples
... gonadal adipose tissue samples of control and obese mice and was proved to be the best for normalizing gene expression in adipose tissue samples of strep- tozotocin-treated animals ...
9
Studies of Human Adipose Tissue ADIPOSE CELL SIZE AND NUMBER IN NONOBESE AND OBESE PATIENTS
... larger adipose cells than do nonobese patients; cell size, however, varies considerably among the fat depots of individuals of either ...total adipose cell number for a given individual based upon cell size ...
14
Site-specific circadian expression of leptin and its receptor in human adipose tissue
... metabolism is driven by different chronobiological rhythms. Whereas many aspects of leptin metabolism and variability have been intensively studied, less is known about its circadian behavior in human ...
8
Effects of acute hypoxia on human adipose tissue lipoprotein lipase activity and lipolysis
... differentiated human preadipocytes and subcu- taneous abdominal adipose tissue biopsies from healthy individuals, we investigated the effects of acute hypoxia on adipose tissue lipid ...
9
Strategies for Human Adipose Tissue Repair and Regeneration
... damaged tissue [11]. Loss or damage of adi- pose tissue needs repair and regenerative approaches not only for the cosmetical impact of absent tissue but also for the emotional well being of the ...
15
Insulin action in human adipose tissue in acromegaly
... investigated. Adipose tissue was obtained from nine patients with acromegaly who had in vivo insulin resistance and from 14 matched healthy control ...
7
Human adipose tissue microvascular endothelial cells secrete PPARγ ligands and regulate adipose tissue lipid uptake
... Figure 4. Effect of OA in PAs. (A–C) Human PAs were starved and incubated without (BAS) or with 300 μM OA or 5 μM ROSI for 24 hours. qRT-PCR of FABP4 (A), CD36 (B), and PPARγ (C); n = 6. *P < 0.05; **P < ...
15
NPC1 in human white adipose tissue and obesity
... The correlation between NPC1 mRNA levels with BMI and waist circumference in humans clearly fits into the concept of NPC1 as an obesity gene. In agreement with this, humans affected by Niemann-Pick syndrome, with mutated ...
5
Characterisation and comparison of adipose tissue macrophages from human subcutaneous, visceral and perivascular adipose tissue
... to human adipose ...of human adipose tissue [4, 18, 19] suggest that an individual ATM might simultaneously bear both M1 and M2 character- istics ...[4]. Adipose tissues isolated ...
9
Gene pathway development in human epicardial adipose tissue during early life
... In summary, the structure and architecture of EAT differs among the neonate, infant, and child, with profound regulatory effects on UCP1 (Figure 6C). EAT retained discrete islands of UCP1-positive cells persisting into ...
14
Association of chemerin mRNA expression in human epicardial adipose tissue with coronary atherosclerosis
... visceral adipose tissue have been considered as the important risk factors for metabolic syndrome and coronary artery disease (CAD) ...[1]. Adipose tissue is now recognized as an active endo- ...
9