Human African Trypanosomiasis (HAT)
Chemotherapy for second-stage Human African trypanosomiasis (Review)
... Human African trypanosomiasis (HAT), or sleeping sickness, is a disease caused by the protozoan parasite Trypanosoma brucei that is transmitted through the bite of infected tsetse ...Essential ...
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Challenges in the control of Human African Trypanosomiasis in the Mpika district of Zambia
... Findings: We conducted a cross-sectional survey of health institutions in Mpika district in Northern Province of Zambia from 9 th to 23 rd November 2011. The aim of this study was to assess current health delivery system ...
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Socioeconomic benefit to individuals of achieving 2020 targets for four neglected tropical diseases controlled/eliminated by innovative and intensified disease management: Human African trypanosomiasis, leprosy, visceral leishmaniasis, Chagas disease
... disease, human African trypanosomiasis (HAT), leprosy and visceral leishmaniasis (VL) are still difficult and costly to manage and available tools are unsuitable for use in large-scale preventive ...
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Towards the Atlas of human African trypanosomiasis
... The human form of tsetse-transmitted trypanosomiasis, also known as sleeping sickness, is a disease unique to Africa that leads to death if ...of human African trypanosomiasis ...
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Epidemiology of human African trypanosomiasis
... Human African trypanosomiasis (HAT), also known as sleeping sickness, is a vector- borne parasitic disease caused by an extracellular protozoa belonging to the genus, Trypanosoma, species, ...
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Diversity of human African trypanosomiasis epidemiological settings requires fine-tuning control strategies to facilitate disease elimination
... Abstract: In 2001, the World Health Organization (WHO) established a public–private partnership to fight human African trypanosomiasis (HAT). As a result of this continuous collaboration, and in ...
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The detection and treatment of human African trypanosomiasis
... Abstract: Human African trypanosomiasis (HAT) is caused by the injection of Trypanosoma brucei (T. b.) gambiense or T. b. rhodesiense by Glossina, the tsetse fly. Three historical eras followed the ...
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HLA G 3’UTR 14 bp Insertion Is Associated with a Decreased Risk of Developing Human African Trypanosomiasis in the Côte d’Ivoire Population
... Human African trypanosomiasis (HAT), or sleeping sickness, caused by Try- panosoma brucei gambiense , is associated with diverse clinical outcomes. Host’s genetic factors involved in immunity are ...
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Human African trypanosomiasis control: Achievements and challenges
... Human African trypanosomiasis (HAT) is a neglected disease that impacts 70 million people living in ...the African trypanosomes transmitted by tsetse flies (Glossina ...animal African ...
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Mathematical Modelling of Human African Trypanosomiasis using Control Measures
... Human African trypanosomiasis (HAT), commonly known as sleeping sickness, is a vector-borne tropical disease which is caused by trypanosoma brucei protozoa ...
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Human African trypanosomiasis of the CNS: current issues and challenges
... Human African trypanosomiasis (HAT), also known as sleeping sickness, comes in two variants: East African and West ...to human health in ...
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Gambian human African trypanosomiasis in North West Uganda Are we on course for the 2020 target?
... In 1994, combined active and passive screening reported 1469 cases from the historic Gambian Human African Trypanosomiasis (gHAT) foci of West Nile, Uganda. Since 2011 systematic active screening has ...
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Village scale persistence and elimination of gambiense human African trypanosomiasis
... Gambiense human African trypanosomiasis (gHAT) is one of several neglected tropical dis- eases that is targeted for elimination by the World Health ...
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The Atlas of human African trypanosomiasis: a contribution to global mapping of neglected tropical diseases
... against African Trypanoso- mosis (PAAT) and the crucial input of National Sleeping Sickness Control Programmes (NSSCPs), Non- Governmental Organizations (NGOs) and Research ...
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Quantitative evaluation of the strategy to eliminate human African trypanosomiasis in the Democratic Republic of Congo
... the human population are both more exposed to the bites of tsetse and never par- ticipate in active screening; this estimate is generated by model fitting rather than social ...
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Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis
... As no single antigen assessed in this study reacted with all the positive sera, combining two or more antigens might be necessary in order to develop a test with a sensitivity that would be sufficiently high for ...
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Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis
... Diagnosis of gambiense HAT is routinely performed following algorithms that include screening to identify suspects, confirmation of disease, and staging to guide the choice of treat- ment [3]. Screening is an important ...
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Serological tests for gambiense human African trypanosomiasis detect antibodies in cattle
... Two categories of samples were used in this study. The first category was blood and sera collected from communally grazed indigenous cattle in a region of mid-northern Uganda that is endemic for rhodesiense HAT, and ...
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WHO interim guidelines for the treatment of gambiense human African trypanosomiasis
... Although the geographical area infested with tsetse flies is very large, HAT has a markedly focal distribution that results from complex and as yet incompletely understood interactions between parasite, vector, host and ...
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Chemotherapy for second-stage Human African trypanosomiasis
... in the Democratic Republic of Congo, Angola, Sudan, Uganda, and the Central African Republic, that resulted in the disruption of whole communities and with huge socioeconomic costs (Seed 2001). In the past few ...
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