human bone marrow stromal cell
Review Article Transdifferentiation between bone and fat on bone metabolism
... adult human trabecular bone have the capacity of adipogenesis when cultured in the presence of 3-isobutyl-1-methylxanthine (IBMX) and dexamethasone ...of bone and fat transdifferentia- tion are ...
8
Hematopoietic Differentiation of Embryoid Bodies Derived from the Human Embryonic Stem Cell Line SNUhES3 in Co culture with Human Bone Marrow Stromal Cells
... irradiated human bone marrow stromal cell layers and cultured with differentiation media composed of IMDM (Invitrogen Corporation, Carlsbad, CA, USA) supplemented with ...single ...
7
Multipotential stromal cell abundance in cellular bone allograft: Comparison with fresh age-matched iliac crest bone and bone marrow aspirate
... immune cell component (lymphocytes and myelomonocytic lineage cells) is removed from Osteo cel cancellous bone by selective washes, any viable cells remaining associated with the allograft could be ...
15
Connexin43 mediates direct intercellular communication in human osteoblastic cell networks
... examined cell coupling and expression of gap junction proteins in monolayer cultures of cells derived from human bone marrow stromal cells (BMC) and trabecular bone osteoblasts ...
10
Potential role of herbal remedies in stem cell therapy: proliferation and differentiation of human mesenchymal stromal cells
... Stem cell therapy has revolutionized modern clinical therapy with the potential of stem cells to differentiate into many different cell types which may help to replace different cell lines of an ...
8
Research on advanced intervention using novel bone marrOW stem cell (RAINBOW): a study protocol for a phase I, open-label, uncontrolled, dose-response trial of autologous bone marrow stromal cell transplantation in patients with acute ischemic stroke
... the bone marrow is extracted from the iliac bone of each patient 15 days or later from the ...allogeneic human platelet lysate (PL) as a substitute for fetal calf serum and are labeled with ...
8
CD146/MCAM defines functionality of human bone marrow stromal stem cell populations
... of bone formed by hMSC-CD146 + and hMSC- CD146 − ...more bone but demonstrated a 10-fold decrease in BM compared with hMSC-CD146 + ...the bone cavity ...more bone and less marrow and ...
13
Phase 1 trial of autologous bone marrow stem cell transplantation in patients with spinal cord injury
... Currently, human oligodendrocyte progenitor cells (OPCs), Schwann cells, bone marrow stromal cells, nasal olfactory ensheathing cells and others are being used for stem cell therapy ...
5
Reduction of MBS85 gene expression after the targeted integration of a transgene into the AAVS1 site using adeno-associated virus integration machinery
... on human chromosome 19 ...a stromal cell line established from human bone marrow cells, and examined the impact of the AAVS1targeted insertion of the transgene on the host ...
7
Simulated microgravity facilitates cell migration and neuroprotection after bone marrow stromal cell transplantation in spinal cord injury
... of cell types, including human neural stem cells [1], embryonic stem (ES) cell derivatives [2,3], and adult bone marrow stromal cells (BMSCs) [4-6], have been transplanted into ...
10
Osteoblast differentiation of NIH3T3 fibroblasts is associated with changes in the IGF-I/IGFBP expression pattern
... of cell growth and ...both human and rat bone marrow stromal cells [6, 8], while they decreased the rate of cell proliferation of mature osteoblasts and osteocytes by inducing ...
14
Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders
... on bone for- mation though activating osteoblasts ...hematopoietic marrow formation in BM [35]. PTH acts on human BM-MSCs to enhance their hematopoietic cell expansion capability through ...
7
Bone marrow-derived mesenchymal stromal cell: what next?
... Abstract: Bone marrow mesenchymal stromal cell (MSC) is a potential alternative in regenerative medicine and has great potential in many pathologic conditions including kidney ...Stem ...
7
Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model
... endothelial cell growth supplement (BD Bio- sciences, Bedford, MA) to confluence in 35-mm plates coated with collagen IV (BD Biosciences) and passaged only one time for ...
16
Stem cell technology for bone regeneration: current status and potential applications
... of bone formation, possess tumorigenic potential by forming ...different cell surface markers for identification. Yet, an unequivocal cell source (or the gold standard) for MSC-based bone ...
10
Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma
... IGFBP7 gene expression is regulated via methylation Exposure of HMCLs to the demethylating agent 5-aza-2′ deoxycytidine (aza) and/or the histone deacetylase inhibi- tor Trichostatin A (TSA) showed significant ...
14
Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation
... Although almost all ADSCs are derived from the white adipose tissue (WAT), as covered in this review, the identification of progenitor cells in brown adipose tissue (BAT) of adult humans is fascinating and worth a ...
10
Stem cell library screen identified ruxolitinib as regulator of osteoblastic differentiation of human skeletal stem cells
... We employed a telomerized hMSC line (hMSC-TERT) as a model for hBMSCs. The hMSC-TERT line was gen- erated through an overexpression of the human telomer- ase reverse transcriptase gene (hTERT). hMSC-TERT exhibits ...
10
3D-bioprinted tracheal reconstruction: an overview
... computerized axial tomography (CT) scan can be used to create quality cross-section images that are then stacked to create a 3D image of the scanned trachea to build per- sonalized TET (Do et al., 2015). PCL has become ...
7
Therapeutic prospects of extracellular vesicles in cancer treatment
... In addition to DCs, macrophages have also been studied as a source of EVs of potential therapeutic benefit. Derived from RAW 264.7 macrophages, vesicles loaded with PTX (exoPTX) were reported to significantly increase ...
10