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Human challenge models with potential respiratory pathogens

Searching for animal models and potential target species for emerging pathogens : Experience gained from Middle East respiratory syndrome (MERS) coronavirus

Searching for animal models and potential target species for emerging pathogens : Experience gained from Middle East respiratory syndrome (MERS) coronavirus

... of potential therapeutic strategies might be imple- mented in ...the human DPP4 (hDDP4) extracellular domain [26], so far, no ro- dent model is naturally permissive for MERS-CoV ...

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In vitro Assessment of the Antimicrobial potential of  Bee’s Honey on some Human Pathogens

In vitro Assessment of the Antimicrobial potential of Bee’s Honey on some Human Pathogens

... Beck et al . (1944) summarized the traditional uses of honey as follows “… its main employment was as a helpful remedy for gastric and intestinal disorders, especially as a pleasant laxative. Respiratory troubles ...

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ANTIMICROBIAL POTENTIAL OF BOSWELLIA SERRATA ROXB. EX. COLEBR.EXTRACTS AGAINST HUMAN PATHOGENS.

ANTIMICROBIAL POTENTIAL OF BOSWELLIA SERRATA ROXB. EX. COLEBR.EXTRACTS AGAINST HUMAN PATHOGENS.

... In the context of the growing problem of multidrug resistant strains of microorganisms, discovery and introduction of novel alternative antimicrobial compounds is a major challenge. Medicinal plants that have been ...

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Revisiting cefditoren for the treatment of community-acquired infections caused by human-adapted respiratory pathogens in adults

Revisiting cefditoren for the treatment of community-acquired infections caused by human-adapted respiratory pathogens in adults

... these potential pathogenic microorganisms have been detected in approximately 25% of patients with chronic obstructive pulmonary disease (COPD) during stable dis- ease ...

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Developing Creativity to Enhance Human Potential in Sport: A Wicked Transdisciplinary Challenge

Developing Creativity to Enhance Human Potential in Sport: A Wicked Transdisciplinary Challenge

... The challenge of developing creativity to enhance human potential is conceptualized as a multifaceted wicked problem due to the countless interactions between people and environments that constitute ...

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The human viral challenge model: accelerating the evaluation of respiratory antivirals, vaccines and novel diagnostics

The human viral challenge model: accelerating the evaluation of respiratory antivirals, vaccines and novel diagnostics

... With the development of molecular technology, it is now possible to refine the statistical analysis by stratify- ing the subjects based on their immune profile. For in- stance, it is now possible to assess whether a ...

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Assessing exhibition swine as potential disseminators of infectious disease through the detection of five respiratory pathogens at agricultural exhibitions

Assessing exhibition swine as potential disseminators of infectious disease through the detection of five respiratory pathogens at agricultural exhibitions

... unique human-animal interface, where exhibiting families and the general public are per- mitted to interact with ...the human population, potentially leading to an influenza ...other pathogens ...

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Control of Invasive Salmonella Disease in Africa: Is There a Role for Human Challenge Models?

Control of Invasive Salmonella Disease in Africa: Is There a Role for Human Challenge Models?

... Human challenge studies can shed light on several of these un- known areas including strain infectivity, duration of stool shed- ding, and detection of early and late disease ...typhoid challenge ...

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Models of respiratory disease symposium

Models of respiratory disease symposium

... from human and in vitro studies is a key factor to meeting the criteria for new model development highlighted above, but will require greater cross-discipline and sector collabora- ...a challenge to the ...

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Outdoor environments and human pathogens in air

Outdoor environments and human pathogens in air

... many pathogens are we exposed to? Is our environment changing and impacting on our health? To answer these questions, we require various techniques to support our research, such as sampling, detection and ...

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Electronic cigarette vapour increases virulence and inflammatory potential of respiratory pathogens

Electronic cigarette vapour increases virulence and inflammatory potential of respiratory pathogens

... the potential contribution of bacterial infection to this path- way is still poorly ...lung pathogens to CSE or ...into potential therapies to reduce the effects of persistent bacterial-induced ...

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Fish: a potential source of bacterial pathogens for human beings 

Fish: a potential source of bacterial pathogens for human beings 

... ABSTRACT: Human infections caused by pathogens transmi�ed from fish or the aquatic environment are quite common and depend on the season, patients’ contact with fish and related environment, dietary habits ...

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Fresh produce as a potential vector for bacterial human pathogens

Fresh produce as a potential vector for bacterial human pathogens

... For Review Only The predicted massive growth in the world overall population and the proportion of the elderly together with climate change and water shortages pose major global challenges in ensuring food security, both ...

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Seasonality of respiratory viruses and bacterial pathogens

Seasonality of respiratory viruses and bacterial pathogens

... the respiratory viral panel (Luminex, Austin, TX), rapid influenza test (Xpert; Ce- pheid, Sunnyvale, CA) or rapid Respiratory Syncytial Virus test (Xpert; Cepheid, Sunnyvale, CA) from an out- patient’s or ...

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Viral Respiratory Pathogens and Lung Injury

Viral Respiratory Pathogens and Lung Injury

... In COVID-19, the persistent high fever, respiratory distress, and acute lung injury that occur as a result of a hyperactivated immune system are the leading causes of dis- ease complexity. Analyses of the COVID-19 ...

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ANTIOXIDANT AND ANTIBACTERIAL POTENTIAL OF MURRAYA KONIGII AGAINST HUMAN CARIOGENIC PATHOGENS

ANTIOXIDANT AND ANTIBACTERIAL POTENTIAL OF MURRAYA KONIGII AGAINST HUMAN CARIOGENIC PATHOGENS

... the potential to generate herbal ...or human health and provide biochemical tools for the study of infectious ...The potential for developing antimicrobials from higher plants appears rewarding as it ...

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Comparison between nasopharyngeal swab and nasal wash, using culture and PCR, in the detection of potential respiratory pathogens

Comparison between nasopharyngeal swab and nasal wash, using culture and PCR, in the detection of potential respiratory pathogens

... of potential pathogens is important as it is both the major source of transmission and the prerequisite of invasive ...detecting potential respiratory pathogens in healthy adults using ...

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Respiratory challenge MRI: practical aspects

Respiratory challenge MRI: practical aspects

... 2016 Respiratory challenge MRI is the modification of arterial oxygen (PaO 2 ) and/or carbon dioxide (PaCO 2 ) concen- tration to induce a change in cerebral function or metabolism which is then measured by ...

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In vitro antagonistic potential of Streptomyces sp  AM S1 against plant and human pathogens

In vitro antagonistic potential of Streptomyces sp AM S1 against plant and human pathogens

... Apart from its antagonistic activity against R. solani, the present isolate Streptomyces sp. AM-S1 exhibited broad antimicrobial spectrum against various plant and human pathogens. Many studies refer to the ...

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CiteSeerX — Potential Source of Opportunistic Pathogens

CiteSeerX — Potential Source of Opportunistic Pathogens

... So, there was no correlation between the simultaneous presence of the fecal indicators and the studied opportunistic pathogens. Therefore, the absence of bacterial indicators or the low level of HPC is not a ...

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