Human Embryonic Stem Cells (HESCs)
LSD1 inhibition yields functional insulin-producing cells from human embryonic stem cells
... beta cells (insulin-producing cells, IPCs) [3]. Human embryonic stem cells (hESCs) repre- sent an attractive source for β-cells production, owing to its ...
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Trophoblast Differentiation of Human Embryonic Stem Cells.
... trophoblast cells from human embryonic stem cells (hESCs) in cell culture is desirable since the availability of trophoblast tissues from very early gestation placentas is ...
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BMP4 directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state
... the human embryo, owing to lack of a proper in vitro model system. Human embryonic stem cells (hESCs) differentiate into functional trophoblast following BMP4 treatment in the ...
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miR 200 and miR 96 families repress neural induction from human embryonic stem cells
... ESC-differentiated cells, including EPI cells upon induction by doxycycline, as indicated by GFP (supplementary ...from hESCs quantified by ...
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Human embryonic stem cells: prospects for development
... hES cells or from co-culture ...differentiating human embryoid bodies, and showed that the cells had properties of fetal or neonatal cardiocytes, as evidenced by their subcellular distribution of gap ...
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Bioprinting of human pluripotent stem cells and their directed differentiation into hepatocyte-like cells for the generation of mini-livers in 3D
... of human induced pluripotent stem cells (hiPSCs), their response to a valve-based printing process as well as their post-printing differentiation into hepatocyte-like cells ...and human ...
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STAT3, stem cells, cancer stem cells and p63
... HER2: Human Epidermal Growth Factor Receptor 2; hESCs: Human Embryonic Stem Cells; HIF-1 α : Hypoxia Inducible Factor Alpha; hMSCS: Human Mesenchymal Stem ...
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Restoration of auditory evoked responses by human ES-cell-derived otic progenitors
... hair cells and their associated spiral ganglion neurons ...hair cells 1 , is responsible for a substantial proportion of patients with hearing impairment 2 ...hair cells can be circumvented partially ...
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Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes
... The discovery of hPSC-CMs, including hPSC-CMs and hESC-CMs, has been an attractive in vitro model to study cardiotoxicity. Many researchers have used hiPSC- CMs and hESC-CMs as screening models for pro- arrhythmic ...
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Directly induced human Schwann cell precursors as a valuable source of Schwann cells
... Schwann cells; iPSC: Induced pluripotent stem cells; hESCs: Human embryonic stem cells; NCSCs: Neural crest stem cells; hPSCs: Human ...
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The pregnancy hormones human chorionic gonadotropin and progesterone induce human embryonic stem cell proliferation and differentiation into neuroectodermal rosettes
... plating, hESCs were plated on this MEF feeder layer and grown in the presence of DMEM-F12 media (Invitrogen) supplemented with 1% NEAA, 1 mM L-glutamine (Invitrogen), ...of cells required colonies to be ...
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Implementation of experimental cellular (cellular-genetic) therapies on the example of eye diseases
... Pluripotent Stem Cells (IPSC) by Shinya Yamanak's team, which ended with the 2012 Nobel Prize ...used stem cells in the therapy of cellular visual diseases are two types of PSC - human ...
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Materials for stem cell factories of the future
... Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and dopaminergic neurons derived from them.. Derivation of human embryonic stem cells in defined[r] ...
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Temporal and partial inhibition of GLI1 in neural stem cells (NSCs) results in the early maturation of NSC derived oligodendrocytes in vitro
... glial cells that are essential for the generation of the myelin sheath around the axonal processes in the mammalian central nervous system [1, ...precursor cells (OPCs) pass through multiple developmental ...
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Human pluripotent stem cells as tools for high-throughput and high-content screening in drug discovery
... discovery. Human pluripotent stem cells (hPSCs) derived either from early human blastocysts (human embryonic stem cells) or by reprogramming somatic cells to ...
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Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations
... Pluripotent stem cells have been derived from various embryonic, fetal and adult ...sources. Embryonic stem cells (ESCs) and parthenogenic ESCs (pESCs) are derived from the ...
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Understanding Megakaryopoiesis And Thrombopoiesis Using Human Stem Cells Models
... Human stem cell models (CD34+ hematopoietic progenitors, embryonic stem cells and induced pluripotent stem cells (iPSCs)) are powerful tools for the study of ...
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MicroRNAs in Human Embryonic and Cancer Stem Cells
... in stem cells. Firstly, miRNAs expre- ssed specifically in ES cells have been ...from stem cells (CSCs) and that many cell signaling pathways essential for normal development are also ...
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Human endogenous retrovirus K (HML 2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells
... the human genome [1], a subset of 11 were found to be expressed in patterns, which varied from cell line to cell line (Table ...all human-specific retroviral integrations fall into this proviral subgroup ...
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3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders
... the human brain makes it difficult to detect all pathological conditions of neuro- logical disorders in ...immune cells, or even blood-brain barrier within organoids would be beneficial for their advanced ...
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