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Human Endogenous Retroviruses

Human Endogenous Retroviruses in Clear Cell Renal Cell Carcinoma: Biological Functions and Clinical Values

<p>Human Endogenous Retroviruses in Clear Cell Renal Cell Carcinoma: Biological Functions and Clinical Values</p>

... Abstract: Human endogenous retroviruses (HERVs) form an important part of the human genome, commonly losing their coding ability and exhibiting only rare expression in healthy tissues to ...

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Identification of a Functional Envelope Protein from the HERV-K Family of Human Endogenous Retroviruses

Identification of a Functional Envelope Protein from the HERV-K Family of Human Endogenous Retroviruses

... Human endogenous retroviruses (HERVs) comprise ap- proximately 8% of the human ...are human specific (17, 20). Actually, the entry dates in the human ge- nome of all six copies ...

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Human endogenous retroviruses: Their possible role in the molecular etiology of the schizophrenia

Human endogenous retroviruses: Their possible role in the molecular etiology of the schizophrenia

... Human endogenous retroviruses (HERVs) represent footprints of previous retroviral ...the human germ line and constitute approximately 8% of our ...

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Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages

Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages

... exogenous retroviruses are thought to have integrated themselves into human germ line cells, becoming part of human DNA and being transmitted over ...such human endogenous ...

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Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV W proviral insertions and processed pseudogenes

Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV W proviral insertions and processed pseudogenes

... SU and TM mature proteins are then linked through a covalent disulphide bond between the SU CWIC and the TM CX6CC motifs. While the TM domain showed a high degree of amino acid homology with respect to Syncytin-1, in the ...

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Identification of a Rev-related protein by analysis of spliced transcripts of the human endogenous retroviruses HTDV/HERV-K.

Identification of a Rev-related protein by analysis of spliced transcripts of the human endogenous retroviruses HTDV/HERV-K.

... The human endogenous retrovirus family HTDV/HERV-K codes for the viral particles observed in teratocarcinoma cell ...In human teratocarcinoma cell lines, both variants are ...

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Differential expression analysis of human endogenous retroviruses based on ENCODE RNA-seq data

Differential expression analysis of human endogenous retroviruses based on ENCODE RNA-seq data

... old endogenous element that is found even outside of primates and shows high similarity to foamy retrovi- ruses [25] and its younger relative ...young human endogenous viral element, which is also ...

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First international workshop on human endogenous retroviruses and diseases, HERVs & disease 2015

First international workshop on human endogenous retroviruses and diseases, HERVs & disease 2015

... novel human retrovirus did not cor- respond to an HTLV-like retrovirus, as suggested by Hilary Koprowski, Robert Gallo and colleagues in a study published in Nature (1985), but to HERVs that were still considered ...

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The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta analysis

The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta analysis

... Multiple Sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS) and one of the most common causes of neurological disability in young adults, with a higher incidence in women than men [1]. ...

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Classification and characterization of human endogenous retroviruses; mosaic forms are common

Classification and characterization of human endogenous retroviruses; mosaic forms are common

... integrated human species-specific HERVK(HML2), still retain some protein coding ...within human DNA over time could be regarded as a balance between “beneficial and detri- mental” effects in the host ...

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Rate of Recombinational Deletion among Human Endogenous Retroviruses

Rate of Recombinational Deletion among Human Endogenous Retroviruses

... of human-specific proviruses lend additional support for the accuracy of our simulation: we observed a mean of nine mutations in these LTRs (n ⫽ 17), and our simulation predicted a mean of ...

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Human endogenous retroviruses sustain complex and cooperative regulation of gene containing loci and unannotated megabase sized regions

Human endogenous retroviruses sustain complex and cooperative regulation of gene containing loci and unannotated megabase sized regions

... Transcription of unannotated regions encompassing several hundred kilobases to almost one megabase is of fundamental interest as the sheer amount of genome sequence and associated RNA splicing patterns suggest ...

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The decline of human endogenous retroviruses: extinction and survival

The decline of human endogenous retroviruses: extinction and survival

... Here we measure the rate of ERV integration in the genome of ancestral humans and other catarrhine pri- mates (Old World monkeys, great apes and gibbons). Multiple catarrhine genomes have been sequenced and their ERVs ...

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Identification, characterization, and comparative genomic distribution of the HERV K (HML 2) group of human endogenous retroviruses

Identification, characterization, and comparative genomic distribution of the HERV K (HML 2) group of human endogenous retroviruses

... zee, human, and orangutan published genomes, but not rhesus genome, consistent with the estimated integra- tion time of the Xq28b provirus (~21 ...of endogenous retroviruses, which have continued ...

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Endogenous retroviruses in the human genome sequence

Endogenous retroviruses in the human genome sequence

... the human genome is that some 45% of our DNA is composed of transposable elements such as LINE and Alu retroelements and DNA transposons ...tious retroviruses, which can be easily recognized because all ...

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Characterizing and Mapping Porcine Endogenous Retroviruses in Westran Pigs

Characterizing and Mapping Porcine Endogenous Retroviruses in Westran Pigs

... defective retroviruses and for recombination of hu- man and porcine retroviruses during ...with human endogenous retroviruses to generate totally novel ...of retroviruses and ...

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Expression Profiles of Endogenous Retroviruses in Old World Monkeys

Expression Profiles of Endogenous Retroviruses in Old World Monkeys

... Human endogenous retroviruses (HERVs) comprise at least 8 to 9% of the human genome. They are associated with both critical biological function such as placental for- mation (6, 28) and with ...

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Endogenous retroviruses and multiple sclerosis–new pieces to the puzzle

Endogenous retroviruses and multiple sclerosis–new pieces to the puzzle

... [19]. Human endogenous retroviruses (HERVs) are rem- nants of prehistoric exogenous retroviruses, integrated in the human genome during primate evolution through germ line ...

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The identification and classification of endogenous retroviruses in the horse genome

The identification and classification of endogenous retroviruses in the horse genome

... known endogenous retroviruses fixed in the domestic horse (equuscaballus) ...other endogenous retrovirus sequences in an equine genome and classify them into ...candidate endogenous ...

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Establishment and Characterization of Molecular Clones of Porcine Endogenous Retroviruses Replicating on Human Cells

Establishment and Characterization of Molecular Clones of Porcine Endogenous Retroviruses Replicating on Human Cells

... The use of pig xenografts is being considered to alleviate the shortage of allogeneic organs for transplan- tation. In addition to the problems overcoming immunological and physiological barriers, the existence of nu- ...

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