Human Epidermal Growth Factor Receptor-2.
The coexpression and prognostic significance of c-MET, fibroblast growth factor receptor 2, and human epidermal growth factor receptor 2 in resected gastric cancer: a retrospective study
... fibroblast growth factor receptor 2 (FGFR2), and human epidermal growth factor receptor 2 (HER2) in human GC and their clinical significance in ...
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Prognostic significance of Human epidermal growth factor receptor 2 expression in patients with resectable gastric adenocarcinoma
... Human epidermal growth factor receptor 2 (HER2), a target used in breast cancer treatment, is the second member of the epidermal growth factor ...
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PIK3CA mutations, phosphatase and tensin homolog, human epidermal growth factor receptor 2, and insulin like growth factor 1 receptor and adjuvant tamoxifen resistance in postmenopausal breast cancer patients
... From paraffin-embedded tissue blocks, 10-μm-thick sec- tions were cut and attached to microscope slides. In total, 10 slides per tumor were used for DNA isolation. Slides were deparaffinized in xylene, rehydrated, and ...
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Detection of Human Epidermal Growth Factor Receptor 2 in Colorectal Tumors
... 19- Nathanosn DR, Alfred T, Culliford IV, Jinru S, Beiyun C, Matthew DA, Zhao-Shi Z, Garrett MN, William G, Francis B, and Philip BP. HER 2/neu EXPRESSION AND GENE AMPLIFICATION IN COLON CANCER Int. J. Cancer. ...
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Role of lapatinib in the first-line treatment of patients with metastatic breast cancer
... of epidermal growth factor receptor (EGFR/ErbB1) and human epidermal growth factor receptor 2 ...
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Pancreatic metastasis from invasive pleomorphic lobular carcinoma of the breast: a rare case report
... estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, E-cadherin, gross cystic disease fluid protein 15 and mammaglobin, which ...
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Clinical potential of novel therapeutic targets in breast cancer: CDK4/6, Src, JAK/STAT, PARP, HDAC, and PI3K/AKT/mTOR pathways
... estrogen receptor α, progesterone receptor, or the human epidermal growth factor receptor 2 (HER2) proto-oncogene account for approximately 90% of cases, and ...
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Positron emission tomography in breast cancer: 18F- FDG and other radiopharmaceuticals
... HER2: Human epidermal growth factor receptor 2; HR: Hormone receptor; IDC: Invasive ductal carcinoma; IHC: Immunohistochemistry; ILC: Invasive lobular carcinoma; ISH: In ...
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The progress of targeted therapy in advanced gastric cancer
... Approximately one million people are diagnosed each year with gastric cancer, making it the fourth most com- mon cancer and the second leading cause of cancer re- lated death worldwide with an estimated 800,000 deaths ...
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6100.pdf
... EGFR(epidermal growth factor receptor) and the related HER-2 (human epidermal growth factor receptor 2) associated with breast cancer has ...
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New developments in the treatment of HER2-positive breast cancer
... Figure 2 Mechanisms of resistance to trastuzumab: (1) epitope masking, such that a cell surface molecule (MUC4) hides the epitope to which trastuzumab binds, preventing recognition and binding of human ...
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Triple-negative breast cancer: new perspectives for targeted therapies
... like, human epidermal growth factor receptor 2, and ...and human epidermal growth factor receptor ...
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Case Report Mammary carcinoma with osteoclast-like giant cells: a case report
... that 2% of breast carci- noma ...estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, receptor activator of nuclear-kB, ...
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Precision medicine in breast cancer: reality or utopia?
... estrogen receptor; PgR: progesterone receptor; AR: androgen receptor; HER2: the oncogenic human epidermal growth factor receptor 2; PTEN: phosphatase and ...
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<p>The Role Of Circulating Tumor DNA In Therapeutic Resistance</p>
... ctDNA-NGS has recently been investigated as a formid- able platform to develop noninvasive blood tests. The purpose of this approach is to complement and further enhance the currently available screening and diagnostic ...
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Receptor conversion in distant breast cancer metastases
... study receptor conversion for estrogen receptor alpha (ERa), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) in a large group ...
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Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis
... of epidermal growth factor receptors (EGFRs) or ERBB receptors has attracted great attention in the literature ...(HER1/c-erbB1), human epidermal growth factor ...
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Immunohistochemical profile and its association with clinicopathological parameters in carcinoma breast: a prospective study in central India
... (PR) receptor and Her-2/neu (human epidermal growth factor receptor type 2) analysis have been accepted as established procedures in routine management of the ...
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Mutations in the phosphatidylinositol 3 kinase pathway: role in tumor progression and therapeutic implications in breast cancer
... of human epidermal growth factor receptor (HER)2 and other receptor tyrosine ...estrogen receptor (ER)+ breast cancer cells, PI3K activation promotes estrogen- ...
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Prognostic Implications of ER, PR and HER2/Neu Protein Expression in a Cohort of Breast Carcinoma
... HER 2/neu was positive in 25% of patients with distant metastasis and ...of human epidermal growth factor receptor including the risk of brain ...predictive factor for ...
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