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Human gut

Temporal and technical variability of human gut metagenomes

Temporal and technical variability of human gut metagenomes

... We collected fecal samples over up to two years from seven subjects to investigate the temporal variability and individuality of the human gut microbiome using meta- genomic shotgun sequencing. To ...

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Evolution and Dynamics of the Human Gut Virome

Evolution and Dynamics of the Human Gut Virome

... Figure 3-4. Reverse transcriptase (RT) sequences found in DNA viruses of the human gut. A) Phylogentic tree of RT sequences. Each sequence was aligned to a position- specific scoring matrix to construct a ...

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Characterization and Detection of a Widely Distributed Gene Cluster That Predicts Anaerobic Choline Utilization by Human Gut Bacteria

Characterization and Detection of a Widely Distributed Gene Cluster That Predicts Anaerobic Choline Utilization by Human Gut Bacteria

... the human gut than in other habitats, potentially due to the high population densities and in- creased metabolic activity in this setting ...among gut microbes has received par- ticular attention ...

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Evidence of Extensive DNA Transfer between Bacteroidales Species within the Human Gut

Evidence of Extensive DNA Transfer between Bacteroidales Species within the Human Gut

... the gut environment into their glycans ...same human gut share many features that are not shared with other, non-coresident members of the same ...

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The Human Gut Microbial Metabolome Modulates Fungal Growth via the TOR Signaling Pathway

The Human Gut Microbial Metabolome Modulates Fungal Growth via the TOR Signaling Pathway

... major human fungal pathogen, but it is also a permanent resident of healthy gastrointestinal ...the human gut microbial metabolome represents an interesting source of bioactive molecules with a ...

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Streamlined Genetic Manipulation of Diverse Bacteroides and Parabacteroides Isolates from the Human Gut Microbiota

Streamlined Genetic Manipulation of Diverse Bacteroides and Parabacteroides Isolates from the Human Gut Microbiota

... the gut microbiota have dramatically increased in recent years as the importance of this microbial ecosystem to human health and disease is better ...healthy human gut and induce both ...

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A human gut phage catalog correlates the gut phageome with type 2 diabetes

A human gut phage catalog correlates the gut phageome with type 2 diabetes

... whole gut bacterial community highly effective protec- tion from being infected by the corresponding ...some gut phages are capable of infecting hosts across the genera in the order ...the gut ...

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Plasticity in the Human Gut Microbiome Defies Evolutionary Constraints

Plasticity in the Human Gut Microbiome Defies Evolutionary Constraints

... and human populations practicing traditional subsistence, relative to primates that rely on diets with the highest content of complex fibers ...the human gut microbiome (39, 40), not all fibers are ...

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Harvesting of Prebiotic Fructooligosaccharides by Nonbeneficial Human Gut Bacteria

Harvesting of Prebiotic Fructooligosaccharides by Nonbeneficial Human Gut Bacteria

... uncultured human gut bacterial species to me- tabolize these functional ...the human gut ...several human gut Firmicutes, including Dorea ...

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Quinones are growth factors for the human gut microbiota

Quinones are growth factors for the human gut microbiota

... The human gut microbiome has been linked to numerous components of health and ...the gut remain uncultured, which limits our ability to properly understand, and exploit, the human ...the ...

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Nitrogen fixation and nifH diversity in human gut microbiota

Nitrogen fixation and nifH diversity in human gut microbiota

... the human gut microbiota truly has a capacity for nitrogen fixa- tion, and if it does, whether it is specific to individuals with low nitrogen intake, remain ...

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Antivirulence Activity of the Human Gut Metabolome

Antivirulence Activity of the Human Gut Metabolome

... the gut microbiota, host cells, and in- vading pathogens and that the sensing events involved could be a critical factor in controlling the balance between health and dis- ...from human feces on microbial ...

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Diversified mcr 1 Harbouring Plasmid Reservoirs Confer Resistance to Colistin in Human Gut Microbiota

Diversified mcr 1 Harbouring Plasmid Reservoirs Confer Resistance to Colistin in Human Gut Microbiota

... and human gut microbiota, (iii) the relatively wide- spread occurrence of mcr-1 in isolates from no fewer than 10 countries is known right now, and (iv) colistin resistance repre- sents a major breach in ...

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The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health

The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health

... The family Christensenellaceae belongs to the bacterial phylum Firmicutes, the phylogenetically diverse and predominant phylum of the human gut microbiome. The name Christensenellaceae is derived from the ...

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Superresolution Imaging Captures Carbohydrate Utilization Dynamics in Human Gut Symbionts

Superresolution Imaging Captures Carbohydrate Utilization Dynamics in Human Gut Symbionts

... Human gut Bacteroidetes promote complex glycan digestion in the gut by coordinated actions of membrane-associated protein com- ...to human health, the pre- cise mechanisms by which these ...

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Metaproteomic analysis of human gut microbiota: where are we heading?

Metaproteomic analysis of human gut microbiota: where are we heading?

... To date, the growing number of metagenomic studies have provided valuable insights into the structure and di- versity of the gut microbial community and their genetic composition. However, it is important to note ...

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Molecular Dissection of Xyloglucan Recognition in a Prominent Human Gut Symbiont

Molecular Dissection of Xyloglucan Recognition in a Prominent Human Gut Symbiont

... resident human gut Bacteroidetes are central to the me- tabolism of the otherwise indigestible complex carbohydrates known as “dietary ...the human-bacterial ...

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Symbiotic Human Gut Bacteria with Variable Metabolic Priorities for Host Mucosal Glycans

Symbiotic Human Gut Bacteria with Variable Metabolic Priorities for Host Mucosal Glycans

... symbiotic gut bacteria possess the ability to degrade multiple polysaccharides, thereby providing nutritional advantages to their ...environments, gut symbionts give different metabolic priorities to ...

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Applying indirect open-circuit calorimetry to study energy expenditure in gnotobiotic mice harboring different human gut microbial communities

Applying indirect open-circuit calorimetry to study energy expenditure in gnotobiotic mice harboring different human gut microbial communities

... with gut microbes from various human donors, and fed representative human di- ets, provides a means for characterizing how gut com- munity members contribute to host energy homeostasis and ...

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Uncovering the trimethylamine-producing bacteria of the human gut microbiota

Uncovering the trimethylamine-producing bacteria of the human gut microbiota

... Target genes were detected in all samples suggesting that TMA producers constitute members of the core gut community, though at very low abundances. In the HMP dataset, 25% of samples were negative for cutC/D and ...

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