human hepatoma cells
Interferon alpha regulates MAPK and STAT1 pathways in human hepatoma cells
... hepatic cells [25]. IFN a- mediated STAT activation is blocked in Huh7 cells containing the HCV genomic replicon ...in human hepatoma ...
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Targeted transfection and expression of hepatitis B viral DNA in human hepatoma cells
... A soluble DNA carrier system consisting of an asialoglycoprotein covalently linked to poly- L-lysine was used to bind DNA and deliver hepatitis B virus (HBV) DNA constructs to asialoglycoprotein receptor-positive ...
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Baculovirus Entry into Human Hepatoma Cells
... Autographa californica multiple nucleopolyhedrovirus (AcMNPV), a prototype member of the Baculoviridae family, has gained increasing interest as a potential vector candidate for mammalian gene delivery applica- tions. ...
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CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin
... Cell cycle arrest was thought to be another major rea- son of cell death induced by anti-tumor drugs [33,34]. Fluorouracil (5-FU) is a pyrimidine analogue which is transformed inside the cell into different cytotoxic me- ...
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Dual regulation of glycogen metabolism by insulin and insulin like growth factors in human hepatoma cells (HEP G2) Analysis with an anti receptor monoclonal antibody
... HEP-G2 cells (a minimal deviation human hepatoma) have insulin receptors and respond to insulin by increasing their glycogen ...HEP-G2 cells, we used 125I-labeled insulin, IGF-I, and IGF-II to ...
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Selective suppression of insulin induced proliferation of cultured human hepatoma cells by somatostatin
... Hep3B. Results showed that both insulin and T3 can stimulate cell growth of serum starved Hep3B cells at physiological concentrations. SRIF alone showed little growth-promoting activity. When added concurrently ...
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Lipoprotein binding to cultured human hepatoma cells
... G2 cells in lipoprotein-containing medium resulted in complete suppression of LDL receptors but did not affect the remnant ...G2 cells seem to be a suitable model for the study of hepatic receptors for ...
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Sulfamoylbenzamide Derivatives Inhibit the Assembly of Hepatitis B Virus Nucleocapsids
... SBAs do not inhibit WHV and DHBV replication. Nucleo- capsid assembly of hepadnaviruses requires the orchestrated in- teraction of multiple viral and host components (45). The process begins with the binding of viral DNA ...
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Hepatitis C Virus Impairs Natural Killer Cell-Mediated Augmentation of Complement Synthesis
... (NK) cells and the complement system play critical roles in the first line of defense against ...NK cells (NK3.3) with human hepatoma cells ...NK cells and the hepatocyte protein ...
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Original Article Development and characterization of pig xenograft model for human hepatocellular carcinoma
... no human hepatocellular carcinoma (HCC) model available in ...large-animal human HCC xenograft model in ...HepG2-GFP cells were delivered into the liver of fifteen three-month-old Bama mini pigs and ...
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Lipoprotein lipase modulates net secretory output of apolipoprotein B in vitro A possible pathophysiologic explanation for familial combined hyperlipidemia
... cultured human hepatoma cells (HepG2) is regulated by rapid reuptake of nascent lipoproteins before they have diffused away from the vicinity of the ...
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Original Article Alhagi-honey and its compound abnormal savda munziq (ASMq) inhibit proliferation and enhance apoptosis of human hepatoma BEL-7402 cells
... in human hepatoma BEL-7402 cells were detected with quantitative real-time ...the cells were col- lected and total RNA was extracted with Trizol (Invitrogen, Carlsbad, CA, ...
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ANTICANCER ACTIVITY OF SESBANIA GRANDIFLORA EXTRACT AGAINST DIETHYL NITROSAMINE INDUCED HEPATIC CARCINOMA
... hepatic cells with intense centrilobular necrosis in DEN intoxicated ...binucleated cells in animals post treated with oral dose of ...positive cells are considered precursors of preneoplastic foci ...
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Hepatitis C Virus NS5A Physically Associates with p53 and Regulates p21/waf1 Gene Expression in a p53-Dependent Manner
... the human MDM2 protein, and hepatitis B virus X protein are known to bind to the transactivation do- main of p53 for inhibition of its functional activity (19, 23, 25, ...mock-transfected cells (A) or ...
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In vitro cytotoxicity and induction of apoptosis by silica nanoparticles in human HepG2 hepatoma cells
... L-02 cells were used to track the biodistribution of silica ...L-02 cells was very ...HepG2 cells was much greater than that localized in the L-02 ...of cells, it can be inferred that the ...
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The secretory core protein of human hepatitis B virus is expressed on the cell surface.
... Expression of HBeAg in a human hepatoma cell line by using recombinant vaccinia viruses revealed that the HBeAg is not only secreted from HBeAg-producing cells but also incorporated into[r] ...
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Activation of Pattern Recognition Receptor-Mediated Innate Immunity Inhibits the Replication of Hepatitis B Virus in Human Hepatocyte-Derived Cells
... Huh7 cells with plasmid expressing TLR adaptors, myeloid differentiation primary response gene 88 (MyD88), and TIR-domain-containing adaptor-inducing beta inter- feron (TRIF), or RIG-I/MDA5 adaptor, interferon ...
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Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy
... key apoptosis executor [32]. It is activated by the death signal and catalyzes the specific cleavage of a variety of apoptosis-related proteins in cells. It plays an important role in multiple pathways of ...
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Cytotoxic effects and the mechanism of three types of magnetic nanoparticles on human hepatoma BEL 7402 cells
... and C-Fe MNPs-treated groups were about 1.94, 1.89, and 2.43 times compared with the control group, respectively. As for cytochrome C, the protein expression slightly decreased at the low concentration, while without ...
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Human Plasmacytoid Dendritic Cells Sense Lymphocytic Choriomeningitis Virus-Infected Cells In Vitro
... by human pDCs in response to coculture with LCMV-infected cells was also related to the exosome-mediated mechanism by which they respond to HCV-infected cells (8, ...9). Human pDC activation ...
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